Selected Aspects of Cisplatin Nephrotoxicity in the Rat and Man

Adriamycin: The Role of Lipid Peroxidation in Cardiac Toxicity and Tumor Response

1977 • 1,116 citations

Enzymatic Defenses of the Mouse Heart Against Reactive Oxygen Metabolites

1980 • 711 citations

A general mechanism for microsomal activation of quinone anticancer agents to free radicals.

1978 • 645 citations

Effect of anthracycline antibiotics on oxygen radical formation in rat heart.

1983 • 634 citations

The Anticancer Agent Adriamycin Can Be Actively Cytotoxic Without Entering Cells

1982 • 578 citations

Generation of free radicals and lipid peroxidation by redox cycling of adriamycin and daunomycin

1977 • 545 citations

Anthracycline antibiotic augmentation of microsomal electron transport and free radical formation.

1977 • 365 citations

Prevention of doxorubicin cardiac toxicity in the mouse by N-acetylcysteine.

1981 • 247 citations

Toxicity of Chemotherapy.

1985 • 170 citations

Generation of free radicals of quinone group-containing anti-cancer chemicals in NADPH-microsome system as evidenced by initiation of sulfite oxidation.

1975 • 154 citations

Differential effects of anthracycline drugs on rat heart and liver microsomal reduced nicotinamide adenine dinucleotide phosphate-dependent lipid peroxidation.

1982 • 86 citations

Lack of age-dependent cisplatin nephrotoxicity

1984 • 84 citations

Circadian stage dependence of cis-diamminedichloroplatinum lethal toxicity in rats.

1982 • 76 citations

Reduction of cis-diamminedichloroplatinum nephrotoxicity in rats by optimal circadian drug timing.

1982 • 74 citations

Circadian time dependence of cisplatin urinary kinetics

1982 • 62 citations

Lethal nephrotoxicity and hematologic toxicity of cis-diamminedichloroplatinum ameliorated by optimal circadian timing and hydration

1982 • 53 citations

Cisplatin urinary pharmacokinetics and nephrotoxicity: a common circadian mechanism.

1982 • 36 citations

Increase of antitumor effect on bleomycin by reduced nicotinamide adenine dinucleotide phosphate and microsomes in vitro and in vivo.

1980 • 5 citations

Increase in the efficacy of low-dose melphalan therapy with progression of mopc-315 plasmacytoma growth. Abstr.

1983 • 1 citations