Vascular endothelial growth factor confers a growth advantage in vitro and in vivo to stromal cells cultured from neonatal hemangiomas.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

Vascular Endothelial Growth Factor Is a Secreted Angiogenic Mitogen

1989 • 4,988 citations

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

1996 • 4,143 citations

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1995 • 3,977 citations

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

1983 • 3,942 citations

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1996 • 3,664 citations

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1993 • 3,605 citations

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1995 • 2,650 citations

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

1989 • 2,267 citations

Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF

1989 • 2,090 citations

The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor

1992 • 2,042 citations

The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing

1991 • 1,991 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.

1994 • 1,661 citations

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

1992 • 1,528 citations

The Vascular Endothelial Growth Factor Family: Identification of a Fourth Molecular Species and Characterization of Alternative Splicing of RNA

1991 • 1,375 citations

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1994 • 1,249 citations

Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR.

1994 • 1,104 citations

Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb

1996 • 980 citations

Vascular permeability factor: a tumor-derived polypeptide that induces endothelial cell and monocyte procoagulant activity, and promotes monocyte migration.

1990 • 857 citations

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.

1993 • 764 citations

How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes memorial Award lecture.

1986 • 744 citations

Cellular markers that distinguish the phases of hemangioma during infancy and childhood.

1994 • 651 citations

Isolation and characterization of a newly identified endothelial cell mitogen produced by AtT-20 cells.

1989 • 497 citations

High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons.

1989 • 469 citations

Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth.

1993 • 460 citations

Clonal growth of bovine vascular endothelial cells: fibroblast growth factor as a survival agent.

1976 • 423 citations

Vasculotropin/Vascular Endothelial Growth Factor Induces Differentiation in Cultured Osteoblasts

1994 • 285 citations

Effect of fibroblast growth factor and lipoproteins on the proliferation of endothelial cells derived from bovine adrenal cortex, brain cortex, and corpus luteum capillaries

1986 • 273 citations

Heat shock induces the release of fibroblast growth factor 1 from NIH 3T3 cells.

1992 • 247 citations

Purification of a glycoprotein vascular endothelial cell mitogen from a rat glioma-derived cell line.

1990 • 230 citations

Human mesangial cells and peripheral blood mononuclear cells produce vascular permeability factor

1993 • 165 citations

Aortic Smooth Muscle Cells Express and Secrete Vascular Endothelial Growth Factor

1991 • 148 citations

In vitro characteristics of endothelium from hemangiomas and vascular malformations.

1982 • 146 citations

Vasculotropin/Vascular endothelial growth factor is an autocrine growth factor for human retinal pigment epithelial cells cultued in vitro

1995 • 146 citations

Vascular growth factors and receptors in capillary hemangioblastomas and hemangiopericytomas.

1996 • 123 citations

Characterization of the receptor to vasculotropin on bovine adrenal cortex-derived capillary endothelial cells.

1990 • 120 citations

Vascular endothelial cell growth factor (VEGF) produced by A-431 human epidermoid carcinoma cells and identification of VEGF membrane binding sites.

1991 • 115 citations

Strong expression of kinase insert domain-containing receptor, a vascular permeability factor/vascular endothelial growth factor receptor in AIDS-associated Kaposi's sarcoma and cutaneous angiosarcoma.

1996 • 108 citations

Expression of Vascular Endothelial Growth Factor in Capillary Hemangioblastoma

1993 • 86 citations

Specific binding of vascular permeability factor to endothelial cells

1991 • 86 citations

Expression of vascular endothelial growth factor and its receptor mRNA in angiosarcoma.

1995 • 83 citations

Expression of Acidic and Basic Fibroblast Growth Factors in Human and Bovine Vascular Smooth Muscle Cells

1990 • 78 citations

Cytofluorometric detection of human endothelial cells in whole blood using S-Endo 1 monoclonal antibody

1991 • 77 citations

Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells

1993 • 66 citations

Diagnostic and therapeutic applications of angiogenesis research.

1993 • 31 citations

Iris-derived melanocytes contain a growth factor that resembles basic fibroblast growth factor

1990 • 13 citations

[Modulation of the tumoral progression by anti-idiotypic antibodies of angiogenesis factors].

1996 • 3 citations