In vitro reconstitution of cdc25 regulated S. cerevisiae adenylyl cyclase and its kinetic properties.

Methods in yeast genetics

1979 • 7,824 citations

Transformation of intact yeast cells treated with alkali cations

1983 • 7,688 citations

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

A highly sensitive adenylate cyclase assay

1974 • 4,213 citations

ras GENES

1987 • 3,818 citations

A Cytoplasmic Protein Stimulates Normal N- ras p21 GTPase, But Does Not Affect Oncogenic Mutants

1987 • 1,197 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

In yeast, RAS proteins are controlling elements of adenylate cyclase

1985 • 1,142 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

Sterile host yeasts (SHY): A eukaryotic system of biological containment for recombinant DNA experiments

1979 • 967 citations

GENETIC CONTROL OF THE CELL DIVISION CYCLE IN YEAST: V. GENETIC ANALYSIS OF cdc MUTANTS

1973 • 728 citations

ras GTPase activating protein: Signal transmitter and signal terminator

1989 • 621 citations

The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway

1987 • 491 citations

Genetic analysis of yeast RAS1 and RAS2 genes

1984 • 460 citations

DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase

1985 • 429 citations

Differential activation of yeast adenylate cyclase by wild type and mutant RAS proteins

1985 • 365 citations

Isolation and characterization of yeast mutants deficient in adenylate cyclase and cAMP-dependent protein kinase.

1982 • 351 citations

Purification of a RAS-Responsive Adenylyl Cyclase Complex from Saccharomyces cerevisiae by Use of an Epitope Addition Method

1988 • 328 citations

Functional homology of mammalian and yeast RAS genes

1985 • 324 citations

From Epinephrine to Cyclic AMP

1988 • 255 citations

IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae.

1989 • 251 citations

CDC25 : a Component of the RAS -Adenylate Cyclase Pathway in Saccharomyces cerevisiae

1987 • 235 citations

Characterization, cloning and sequence analysis of the CDC25 gene which controls the cyclic AMP level of Saccharomyces cerevisiae.

1986 • 232 citations

Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae.

1987 • 230 citations

Reconstitution of catecholamine-stimulated adenylate cyclase activity using three purified proteins.

1985 • 206 citations

Adenylate cyclase activation by the .beta.-adrenergic receptors as a diffusion-controlled process

1979 • 199 citations

Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae.

1989 • 162 citations

Beta-adrenergic receptors and their mode of coupling to adenylate cyclase

1986 • 126 citations

A guanine nucleotide-sensitive adenylate cyclase in the yeast Saccharomyces cerevisiae.

1983 • 124 citations

Requirement of One Functional RAS Gene and Inability of an Oncogenic ras Variant to Mediate the Glucose-Induced Cyclic AMP Signal in the Yeast Saccharomyces cerevisiae

1988 • 115 citations

Isolation of the gene encoding adenylate cyclase in Saccharomyces cerevisiae.

1985 • 108 citations

Cyclic AMP-dependent phosphorylation of fructose-1,6-bisphosphatase in yeast

1982 • 103 citations

Coupling of a single adenylate cyclase of two receptors: adenosine and catecholamine

1978 • 102 citations

A role for Ni in the hormonal stimulation of adenylate cyclase

1985 • 99 citations

Reconstitution of beta 1-adrenoceptor-dependent adenylate cyclase from purified components.

1986 • 97 citations

Suppression of defective RAS1 and RAS2 functions in yeast by an adenylate cyclase activated by a single amino acid change.

1986 • 93 citations

Glucose‐induced cAMP signaling in Saccharomyces cerevisiae is mediated by the CDC25 protein

1989 • 87 citations

Initiation of meiosis in cell cycle initiation mutants of Saccharomyces cerevisiae

1978 • 84 citations

Mechanism of control of adenylate cyclase activity in yeast by fermentable sugars and carbonyl cyanide m-chlorophenylhydrazone.

1986 • 77 citations

IRA1, an Inhibitory Regulator of the RAS-Cyclic AMP Pathway in Saccharomyces cerevisiae

1989 • 64 citations

A new RAS mutation that suppresses the CDC25 gene requirement for growth of Saccharomyces cerevisiae.

1988 • 52 citations

The Activation of Adenylate Cyclase by Guanyl Nucleotides in Saccharomyces cerevisiae Is Controlled by the CDC25 Start Gene Product

1987 • 49 citations

Interaction of cAMP with the CDC25-mediated step in the cell cycle of budding yeast

1986 • 42 citations

The ras gene family.

1986 • 37 citations

Dominant Yeast and Mammalian RAS Mutants That Interfere with the CDC25-Dependent Activation of Wild-Type RAS in Saccharomyces cerevisiae

1989 • 35 citations

Expression of normal and activated human Ha-ras cDNAs in Saccharomyces cerevisiae.

1985 • 33 citations

Adenylyl cyclase in yeast. Hydrodynamic properties and activation by trypsin.

1987 • 30 citations

Clones from two different genomic regions complement the cdc25 start mutation of Saccharomyces cerevisiae

1986 • 28 citations

A New RAS Mutation That Suppresses the CDC25 Gene Requirement for Growth of Saccharomyces cerevisiae

1988 • 14 citations

An altered adenylate cyclase in cdc35-1 cell division cycle mutant of yeast

1986 • 6 citations