Influence of steel factor on hemoglobin synthesis in sickle cell disease

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

1990 • 870 citations

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

1990 • 837 citations

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles

1990 • 632 citations

Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia.

1984 • 514 citations

5-Azacytidine Selectively Increases γ-Globin Synthesis in a Patient with β⁺Thalassemia

1982 • 496 citations

Gonadal expression of c-kit encoded at the W locus of the mouse

1990 • 479 citations

5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons.

1982 • 396 citations

Developmental expression of c-kit, a proto-oncogene encoded by the W locus

1990 • 349 citations

Hematologic Responses of Patients with Sickle Cell Disease to Treatment with Hydroxyurea

1990 • 289 citations

Levels of Fetal Hemoglobin Necessary for Treatment of Sickle Cell Disease

1988 • 230 citations

Treatment of Sickle Cell Anemia with Hydroxyurea and Erythropoietin

1990 • 202 citations

Hydroxyurea-induced augmentation of fetal hemoglobin production in patients with sickle cell anemia

1987 • 202 citations

Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells

1991 • 202 citations

Isolation of c-kit receptor-expressing cells from bone marrow, peripheral blood, and fetal liver: functional properties and composite antigenic profile

1991 • 188 citations

The immunologic detection of minimal residual disease in acute leukemia [published erratum appears in Blood 1990 Nov 1;76(7):1901]

1990 • 186 citations

Stimulation of F-Cell Production in Patients with Sickle-Cell Anemia Treated with Cytarabine or Hydroxyurea

1985 • 160 citations

Stimulation of Fetal Hemoglobin Synthesis by Erythropoietin in Baboons

1987 • 150 citations

Recombinant human stem cell factor, a c-kit ligand, stimulates hematopoiesis in primates

1991 • 133 citations

Butyrate infusions in the ovine fetus delay the biologic clock for globin gene switching.

1988 • 132 citations

Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia

1989 • 126 citations

Influence of murine mast cell growth factor (c-kit ligand) on colony formation by mouse marrow hematopoietic progenitor cells.

1991 • 106 citations

HAEMOGLOBIN SYNTHESIS DURING HUMAN FETAL DEVELOPMENT

1976 • 91 citations

High fetal hemoglobin production in sickle cell anemia in the eastern province of Saudi Arabia is genetically determined

1986 • 80 citations

alpha-Amino-N-butyric acid stimulates fetal hemoglobin in the adult

1988 • 70 citations

Combinations of recombinant colony-stimulating factors are required for optimal hematopoietic differentiation in serum-deprived culture

1989 • 64 citations

Sickle cell anemia and trait in a population of southern india

1977 • 43 citations

Influence of recombinant hematopoietins and of fetal bovine serum on the globin synthetic pattern of human BFUe

1990 • 37 citations

Serum-free culture of enriched hematopoietic progenitors reflects physiologic levels of fetal hemoglobin biosynthesis

1990 • 34 citations

Granulocyte-macrophage colony-stimulating factor reactivates fetal hemoglobin synthesis in erythroblast clones from normal adults

1989 • 30 citations

Fetal calf serum contains activities that induce fetal hemoglobin in adult erythroid cell cultures

1990 • 30 citations

Hydroxyurea-induced augmentation of fetal hemoglobin production in patients with sickle cell anemia

1987 • 24 citations

Direct evidence for interaction between human erythroid progenitor cells and a hemoglobin switching activity present in fetal sheep serum.

1983 • 22 citations

Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells

1991 • 22 citations

Recombinant human stem cell factor, a c-kit ligand, stimulates hematopoiesis in primates

1991 • 21 citations

Radio-ligand immunoassay for human hemoglobin variants

1981 • 21 citations

Determination of the hemoglobin F program in human progenitor-derived erythroid cells.

1985 • 20 citations

Fetal hemoglobin accumulation in vitro. Effect of adherent mononuclear cells.

1983 • 16 citations

Increasing fetal hemoglobin production in sickle cell disease: results of clinical trials.

1987 • 14 citations

Gamma-interferon alters globin gene expression in neonatal and adult erythroid cells

1987 • 12 citations

Combinations of recombinant colony-stimulating factors are required for optimal hematopoietic differentiation in serum-deprived culture

1989 • 9 citations

Fetal calf serum contains activities that induce fetal hemoglobin in adult erythroid cell cultures

1990 • 1 citations