Recombinant Human Thrombopoietin in Combination With Granulocyte Colony-Stimulating Factor Enhances Mobilization of Peripheral Blood Progenitor Cells, Increases Peripheral Blood Platelet Concentration, and Accelerates Hematopoietic Recovery Following High-Dose Chemotherapy

Nonparametrics: Statistical Methods Based on Ranks

1979 • 3,437 citations

Nonparametrics: Statistical Methods Based on Ranks.

1976 • 2,118 citations

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand

1994 • 1,328 citations

Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo

1994 • 1,138 citations

Promotion of megakaryocyte progenitor expansion and differentiation by the c-Mpl ligand thrombopoietin

1994 • 1,081 citations

Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor MpI

1994 • 987 citations

Leukocyte Reduction and Ultraviolet B Irradiation of Platelets to Prevent Alloimmunization and Refractoriness to Platelet Transfusions

1997 • 761 citations

Thrombopoietin: the primary regulator of platelet production [see comments]

1995 • 691 citations

c-Mpl ligand is a humoral regulator of megakaryocytopoiesis

1994 • 689 citations

Factors that influence collection and engraftment of autologous peripheral-blood stem cells.

1995 • 659 citations

The Threshold for Prophylactic Platelet Transfusions in Adults with Acute Myeloid Leukemia

1997 • 572 citations

High-dose chemotherapy with hematopoietic rescue as primary treatment for metastatic breast cancer: a randomized trial.

1995 • 415 citations

Autologous transplantation with peripheral blood mononuclear cells collected after administration of recombinant granulocyte stimulating factor

1993 • 382 citations

How Should Relative Changes be Measured?

1985 • 339 citations

Effects of Polyethylene Glycol–Conjugated Recombinant Human Megakaryocyte Growth and Development Factor on Platelet Counts after Chemotherapy for Lung Cancer

1997 • 298 citations

Granulocyte colony-stimulating factor "mobilized" peripheral blood progenitor cells accelerate granulocyte and platelet recovery after high-dose chemotherapy

1993 • 292 citations

The Mpl receptor is expressed in the megakaryocytic lineage from late progenitors to platelets

1995 • 286 citations

Optimizing dose and scheduling of filgrastim (granulocyte colony- stimulating factor) for mobilization and collection of peripheral blood progenitor cells in normal volunteers [see comments]

1995 • 273 citations

Thrombopoietin expands erythroid progenitors, increases red cell production, and enhances erythroid recovery after myelosuppressive therapy.

1995 • 269 citations

Stimulation of Megakaryocyte and Platelet Production by a Single Dose of Recombinant Human Thrombopoietin in Patients with Cancer

1997 • 226 citations

Randomized, Blinded, Placebo-Controlled Phase I Trial of Pegylated Recombinant Human Megakaryocyte Growth and Development Factor With Filgrastim After Dose-Intensive Chemotherapy in Patients With Advanced Cancer

1997 • 206 citations

Ultrastructure of Platelet Formation by Human Megakaryocytes Cultured With the Mpl Ligand

1997 • 196 citations

Granulocyte colony-stimulating factor accelerates neutrophil engraftment following peripheral-blood stem-cell transplantation: a prospective, randomized trial.

1995 • 184 citations

Megakaryocytic Progenitors Can Be Generated Ex Vivo and Safely Administered to Autologous Peripheral Blood Progenitor Cell Transplant Recipients

1997 • 179 citations

Bone marrow autotransplantation for solid tumors--prospects.

1989 • 175 citations

High-dose therapy followed by autologous peripheral-blood stem-cell transplantation for patients with Hodgkin's disease and non-Hodgkin's lymphoma using unprimed and granulocyte colony-stimulating factor-mobilized peripheral-blood stem cells.

1994 • 140 citations

Human Platelets Display High-Affinity Receptors for Thrombopoietin

1997 • 137 citations

Effects of Cytokines on Platelet Production From Blood and Marrow CD34+ Cells

1998 • 132 citations

Thrombopoietin stimulates megakaryocytopoiesis, myelopoiesis, and expansion of CD34+ progenitor cells from single CD34+Thy-1+Lin- primitive progenitor cells

1996 • 129 citations

The Efficacy of Single-Dose Administration of Thrombopoietin With Coadministration of Either Granulocyte/Macrophage or Granulocyte Colony-Stimulating Factor in Myelosuppressed Rhesus Monkeys

1997 • 85 citations

High-dose chemotherapy and stem-cell rescue in the treatment of high-risk breast cancer: prognostic indicators of progression-free and overall survival.

1997 • 81 citations

A Single Injection of Pegylated Murine Megakaryocyte Growth and Development Factor (MGDF ) Into Mice Is Sufficient to Produce a Profound Stimulation of Megakaryocyte Frequency, Size, and Ploidization

1997 • 63 citations

In vivo adenovirus vector-mediated transfer of the human thrombopoietin cDNA maintains platelet levels during radiation-and chemotherapy- induced bone marrow suppression

1996 • 52 citations

Effect of CD34+ Selection and Various Schedules of Stem Cell Reinfusion and Granulocyte Colony-Stimulating Factor Priming on Hematopoietic Recovery After High-Dose Chemotherapy for Breast Cancer

1997 • 49 citations

Thrombopoietin mobilizes CD34+ cell subsets into peripheral blood and expands multilineage progenitors in bone marrow of cancer patients with normal hematopoiesis.

1998 • 34 citations