p53 gene mutations in multiple myeloma are associated with advanced forms of malignancy

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

p53 Mutations in Human Cancers

1991 • 8,133 citations

The p53 tumour suppressor gene

1991 • 3,871 citations

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

1989 • 3,557 citations

A clinical staging system for multiple myeloma correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival

1975 • 3,051 citations

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

Mutational hot spot in the p53 gene in human hepatocellular carcinomas

1991 • 1,525 citations

Selective G to T mutations of p53 gene in hepatocellular carcinoma from southern Africa

1991 • 1,418 citations

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

1989 • 1,214 citations

p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.

1990 • 1,080 citations

p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia.

1991 • 915 citations

Clonal expansion of p53 mutant cells is associated with brain tumour progression

1992 • 687 citations

Structural aspects of the p53 protein in relation to gene evolution.

1990 • 618 citations

Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells.

1981 • 576 citations

High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene.

1989 • 383 citations

Plasma cell myeloma--new biological insights and advances in therapy

1989 • 299 citations

Frequent Mutations in the p53 Tumor Suppressor Gene in Human Leukemia T-Cell Lines

1990 • 296 citations

Plasma cell leukemia. Report on 17 cases

1974 • 281 citations

A uniform deleting element mediates the loss of κ genes in human B cells

1985 • 259 citations

Different Tumor-Derived p53 Mutants Exhibit Distinct Biological Activities

1990 • 245 citations

Analysis of RAS oncogene mutations in human lymphoid malignancies.

1988 • 226 citations

Combination chemotherapy for multiple myeloma

1972 • 213 citations

P53 gene mutations in acute myeloid leukemia with 17p monosomy

1991 • 184 citations

Ras oncogene mutation in multiple myeloma.

1989 • 176 citations

Evidence that p53 behaves as a tumour suppressor gene in sporadic breast tumours.

1990 • 165 citations

Mutations in the p53 gene in myelodysplastic syndromes.

1991 • 123 citations

Plasma Cell Myeloma

1989 • 17 citations

Analysis of tumor‐specific immunoglobulin gene rearrangement in peripheral blood B‐cells of multiple myeloma patients

1991 • 12 citations