P53 gene mutations in acute myeloid leukemia with 17p monosomy

Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

1989 • 3,557 citations

Proposed Revised Criteria for the Classification of Acute Myeloid Leukemia

1985 • 2,981 citations

Mutations in the p53 gene occur in diverse human tumour types

1989 • 2,765 citations

Chromosome 17 Deletions and p53 Gene Mutations in Colorectal Carcinomas

1989 • 2,081 citations

The p53 proto-oncogene can act as a suppressor of transformation

1989 • 2,019 citations

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus.

1988 • 1,582 citations

Mutational hot spot in the p53 gene in human hepatocellular carcinomas

1991 • 1,525 citations

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

1989 • 1,214 citations

p53: oncogene or anti-oncogene?

1990 • 812 citations

Detection of p53 Gene Mutations in Human Brain Tumors by Single-strand Conformation Polymorphism Analysis of Polymerase Chain Reaction Products

1991 • 556 citations

Localization of gene for human p53 tumour antigen to band 17p13

1986 • 498 citations

Frequent Mutations in the p53 Tumor Suppressor Gene in Human Leukemia T-Cell Lines

1990 • 296 citations

Chromosome aberrations and prognostic factors in therapy-related myelodysplasia and acute nonlymphocytic leukemia

1990 • 288 citations

Human p53 cellular tumor antigen: cDNA sequence and expression in COS cells.

1985 • 227 citations

Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas.

1991 • 200 citations

Evidence that p53 behaves as a tumour suppressor gene in sporadic breast tumours.

1990 • 165 citations

Cloning and characterization of a cDNA from Xenopus laevis coding for a protein homologous to human and murine p53.

1987 • 158 citations

Rearrangements in the p53 gene in Philadelphia chromosome positive chronic myelogenous leukemia [see comments]

1989 • 157 citations

Rearrangement and expression of p53 in the chronic phase and blast crisis of chronic myelogenous leukemia

1990 • 138 citations

Mutation of the p53 gene in human acute myelogenous leukemia

1991 • 128 citations

Mutations of the p53 gene in lymphoid leukemia

1991 • 104 citations

Identification and characterization of a p53 gene mutation in a human osteosarcoma cell line.

1989 • 94 citations

Translocations (5;17) and (7;17) in patients with de novo or therapy-related myelodysplastic syndromes or acute nonlymphocytic leukemia

1990 • 30 citations