Patterns of p53 mutations in squamous cell carcinoma of the lung: Acquisition at a relatively early age

p53 Mutations in Human Cancers

1991 • 8,133 citations

The Clonal Evolution of Tumor Cell Populations

1976 • 6,310 citations

p53 function and dysfunction

1992 • 1,918 citations

Mutator phenotype may be required for multistage carcinogenesis.

1991 • 1,327 citations

Mutational Activation of the K-rasOncogene

1987 • 542 citations

Mutations in the p53 gene are frequent in primary, resected non-small cell lung cancer. Lung Cancer Study Group.

1990 • 515 citations

Development of carcinoma of the lung as reflected in exfoliated cells

1974 • 422 citations

Detection of oncogene mutations in sputum precedes diagnosis of lung cancer

1994 • 403 citations

Deletion of a DNA sequence at the chromosomal region 3p21 in all major types of lung cancer

1987 • 396 citations

Molecular Analysis of the Short Arm of Chromosome 3 in Small-Cell and Non-Small-Cell Carcinoma of the Lung

1987 • 331 citations

Mutations of p53 and ras genes in radon-associated lung cancer from uranium miners

1992 • 315 citations

p53 Mutations in non-small cell lung cancer in Japan: Association between mutations and smoking

1992 • 280 citations

p53 and chromosome 3 abnormalities, characteristic of malignant lung tumours, are detectable in preinvasive lesions of the bronchus

1993 • 256 citations

Deletions of 17p and p53 mutations in preneoplastic lesions of the lung.

1992 • 254 citations

ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent.

1991 • 249 citations

Aberrations of the p53 tumor suppressor gene in human non-small cell carcinomas of the lung

1993 • 180 citations

p53 mutations in human lung tumors.

1992 • 177 citations

c-K-ras and p53 mutations occur very early in adenocarcinoma of the lung

1995 • 127 citations

Specific genetic analysis of microscopic tissue after selective ultraviolet radiation fractionation and the polymerase chain reaction.

1992 • 126 citations

Concurrent p53 expression in bronchial dysplasias and squamous cell lung carcinomas.

1993 • 99 citations

p53 mutations in lung tumors: relationship to putative susceptibility markers for cancer.

1994 • 96 citations

Use of the single strand conformation polymorphism technique and PCR to detect p53 gene mutations in small cell lung cancer.

1991 • 83 citations

Smoking and lung cancer with special regard to type of smoking and type of cancer. A case-control study in north Sweden

1986 • 69 citations

p53 mutations in primary human lung tumors and their metastases

1994 • 56 citations

Application of the p53 Gene Mutation Pattern for Differential Diagnosis of Primary Versus Metastatic Lung Carcinomas

1993 • 42 citations

DNA aberrations at the retinoblastoma gene locus in human squamous cell carcinomas of the lung.

1994 • 26 citations

Relationships of morphology to clinical presentation in ten cases of early squamous cell carcinoma of the lung

1976 • 26 citations