Psychopharmacology of olanzapine

The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia

1987 • 19,723 citations

A New Depression Scale Designed to be Sensitive to Change

1979 • 12,729 citations

The Brief Psychiatric Rating Scale

1962 • 10,683 citations

ECDEU Assessment Manual for Psychopharmacology

1976 • 8,729 citations

The Global Assessment Scale

1976 • 4,944 citations

Clozapine for the Treatment-Resistant Schizophrenic

1988 • 4,030 citations

Scale for the Assessment of Negative Symptoms (SANS)*

1989 • 2,588 citations

Radioreceptor Binding Profile of the Atypical Antipsychotic Olanzapine

1996 • 1,047 citations

Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial

1997 • 906 citations

Serotonin-dopamine interaction and its relevance to schizophrenia

1996 • 822 citations

Olanzapine versus Placebo and Haloperidol

1996 • 788 citations

Double-Blind Comparison of Olanzapine Versus Risperidone in the Treatment of Schizophrenia and Other Psychotic Disorders

1997 • 722 citations

Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons

1983 • 680 citations

Differential Effects of Classical and Atypical Antipsychotic Drugs on A9 and A10 Dopamine Neurons

1983 • 589 citations

Neuroleptics increase C-FOS expression in the forebrain: Contrasting effects of haloperidol and clozapine

1992 • 477 citations

Olanzapine versus placebo: results of a double-blind, fixed-dose olanzapine trial

1996 • 387 citations

Induction patterns of Fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity.

1994 • 304 citations

Blind, controlled, long-term study of the comparative incidence of treatment-emergent tardive dyskinesia with olanzapine or haloperidol

1997 • 287 citations

Olanzapine versus haloperidol: acute phase results of the international double-blind olanzapine trial

1997 • 284 citations

The behavioral pharmacology of olanzapine, a novel "atypical" antipsychotic agent.

1992 • 264 citations

Mechanisms of action of atypical antipsychotic drugs

1991 • 254 citations

Antipsychotic agents antagonize non-competitiveN-methyl-d-aspartate antagonist-induced behaviors

1995 • 248 citations

Regionally specific effects of atypical antipsychotic drugs on striatal Fos expression: The nucleus accumbens shell as a locus of antipsychotic action

1992 • 238 citations

Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice

1997 • 216 citations

Clozapine, single photon emission tomography, and the D2 dopamine receptor blockade hypothesis of schizophrenia

1992 • 207 citations

Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine.

1996 • 200 citations

Pharmacologic activation of limbic structures and neuroimaging studies of emotions.

1997 • 196 citations

Antagonism of phencyclidine-induced deficits in prepulse inhibition by the putative atypical antipsychotic olanzapine

1995 • 194 citations

Extrapyramidal Symptoms and Tolerability of Olanzapine Versus Haloperidol in the Acute Treatment of Schizophrenia

1997 • 171 citations

The New Atypical Antipsychotics

1994 • 168 citations

In vitro and in vivo biochemistry of olanzapine: a novel, atypical antipsychotic drug.

1997 • 155 citations

Effects of Olanzapine on Regional C-Fos Expression in Rat Forebrain

1996 • 140 citations

Atypical antipsychotic drugs as a first-line treatment of schizophrenia: a rationale and hypothesis.

1996 • 139 citations

Oral olanzapine versus oral haloperidol in the maintenance treatment of schizophrenia and related psychoses

1998 • 137 citations

A PET Study of 5-HT2 and D2 Dopamine Receptor Occupancy Induced by Olanzapine in Healthy Subjects

1997 • 132 citations

Neurochemical evidence for antagonism by olanzapine of dopamine, serotonin, α1-adrenergic and muscarinic receptors in vivo in rats

1996 • 131 citations

Dopamine D2 receptor occupancy in vivo by the novel atypical antipsychotic olanzapine — a123 IBZM single photon emission tomography (SPET) study

1996 • 124 citations

Electrophysiological Effects of Olanzapine, a Novel Atypical Antipsychotic, on A9 and A10 Dopamine Neurons

1996 • 122 citations

In vitro interaction of the antipsychotic agent olanzapine with human cytochromes P450 CYP2C9, CYP2C19, CYP2D6 and CYP3A

1996 • 103 citations

Efficacy of olanzapine: an overview of pivotal clinical trials.

1997 • 102 citations

Olanzapine in Treatment-Refractory Schizophrenia

1997 • 72 citations

Transepithelial transport properties of peptidomimetic thrombin inhibitors in monolayers of a human intestinal cell line (Caco-2) and their correlation to in vivo data.

1995 • 54 citations

Neuroendocrine evidence for antagonism of serotonin and dopamine receptors by olanzapine (LY170053), an antipsychotic drug candidate.

1992 • 48 citations

First clinical experience with olanzapine (LY 170053)

1995 • 41 citations

Behavioral pharmacology of olanzapine: a novel antipsychotic drug.

1997 • 40 citations

The olfactory tubercle as a site of action of neuroleptics with an atypical profile in the paw test: effect of risperidone, prothipendyl, ORG 5222, sertindole and olanzapine

1995 • 31 citations

The effect of clozapine on Fos protein immunoreactivity in the rat forebrain is not mimicked by the addition of α1-adrenergic or 5HTZ receptor blockade to haloperidol

1995 • 26 citations

The moderate affinity of clozapine at H3 receptors is not shared by its two major metabolites and by structurally related and unrelated atypical neuroleptics

1996 • 23 citations

THE USE OF OLANZAPINE IN NON-COMPLIANT OR TREATMENT-RESISTANT CLOZAPINE POPULATIONS IN HOSPITAL

1998 • 18 citations

High dose olanzapine in treatment resistant schizophrenia

1998 • 13 citations

Efficacy of a 12 week trial of olanzapine in treatment refractory schizophrenia or schizoaffective disorder

1998 • 12 citations