Priming immunization against cholera toxin and E. coli heat-labile toxin by a cholera toxin short peptide-beta-galactosidase hybrid synthesized in E. coli.

In vitro gene fusions that join an enzymatically active beta-galactosidase segment to amino-terminal fragments of exogenous proteins: Escherichia coli plasmid vectors for the detection and cloning of translational initiation signals

1980 • 1,052 citations

Femtomole sensitive radioimmunoassay for cyclic AMP and cyclic GMP after 2'0 acetylation by acetic anhydride in aqueous solution.

1975 • 932 citations

Preferential codon usage in prokaryotic genes: the optimal codon-anticodon interaction energy and the selective codon usage in efficiently expressed genes

1982 • 850 citations

ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase.

1978 • 732 citations

Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development

1983 • 645 citations

Infectious vaccinia virus recombinants that express hepatitis B virus surface antigen

1983 • 422 citations

Interaction of cholera toxin and membrane GM1 ganglioside of small intestine.

1975 • 367 citations

The arrangement of subunits in chlorea toxin

1976 • 337 citations

Priming for and induction of anti-poliovirus neutralizing antibodies by synthetic peptides

1983 • 234 citations

Enzymic activity of cholera toxin. II. Relationships to proteolytic processing, disulfide bond reduction, and subunit composition.

1979 • 230 citations

Construction of live vaccines by using genetically engineered poxviruses: biological activity of recombinant vaccinia virus expressing influenza virus hemagglutinin.

1983 • 225 citations

Expression of Plasmodium falciparum Circumsporozoite Proteins in Escherichia coli for Potential Use in a Human Malaria Vaccine

1985 • 210 citations

Recombinant nontoxinogenic Vibrio cholerae strains as attenuated cholera vaccine candidates

1984 • 198 citations

Open reading frame expression vectors: a general method for antigen production in Escherichia coli using protein fusions to beta-galactosidase.

1983 • 108 citations

Antibodies against synthetic peptides of the B subunit of cholera toxin: crossreaction and neutralization of the toxin.

1983 • 98 citations

Antitoxic Immunity in Experimental Cholera: Comparison of Immunity Induced Perorally and Parenterally in Mice

1972 • 88 citations

Immunity and protection against influenza virus by synthetic peptide corresponding to antigenic sites of hemagglutinin.

1984 • 85 citations

INTESTINAL ANTIBODY RESPONSES AFTER IMMUNISATION WITH CHOLERA B SUBUNIT

1982 • 81 citations

Synthetic vaccines

1983 • 54 citations

Neutralization of heat-labile toxin of E. coli by antibodies to synthetic peptides derived from the B subunit of cholera toxin.

1984 • 47 citations

Both cholera toxin-induced adenylate cyclase activation and cholera toxin biological activity are inhibited by antibodies against related synthetic peptides.

1984 • 35 citations

cAMP-dependent protein kinase from mouse thymocytes. Localization, characterization, and evaluation of the physiological relevance of a massive cytosol to nucleus translocation.

1979 • 33 citations

A Randomized, Controlled Trial of the Toxin-Blocking Effects of B Subunit in Family Members of Patients with Cholera

1984 • 18 citations

Recombinant DNA technology for the preparation of subunit vaccines.

1982 • 16 citations

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