Gene Cloning and Organization of the Alpha-Toxin of Clostridium perfringens

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Bergey's Manual of Determinative Bacteriology

1975 • 11,384 citations

Leukotrienes: Mediators of Immediate Hypersensitivity Reactions and Inflammation

1983 • 2,839 citations

Bergey's Manual of Determinative Bacteriology

1975 • 2,833 citations

Improved Estimation of Secondary Structure in Ribonucleic Acids

1973 • 2,302 citations

The biochemistry of bacterial toxins

1941 • 522 citations

Bacterial toxins and cell membranes

1978 • 471 citations

High-resolution (1.5 Å) crystal structure of phospholipase C from Bacillus cereus

1989 • 451 citations

Bacterial phospholipases C

1993 • 420 citations

Bacterial Protein Toxins: An Overview

2003 • 335 citations

Iron regulation of Shiga-like toxin expression in Escherichia coli is mediated by the fur locus

1987 • 331 citations

In vivo and in vitro transcription of the Clostridium pasteurianum ferredoxin gene. Evidence for "extended" promoter elements in gram-positive organisms.

1986 • 252 citations

Constitutive function of a positively regulated promoter reveals new sequences essential for activity.

1987 • 246 citations

Pharmacology of bacterial toxins

1986 • 232 citations

PHARMACOLOGY OF BACTERIAL TOXINS.

1964 • 192 citations

Recent advances in the genetics of the clostridia

1989 • 181 citations

Molecular cloning and nucleotide sequence of the alpha-toxin (phospholipase C) of Clostridium perfringens

1989 • 177 citations

Genome organization of the anaerobic pathogen Clostridium perfringens.

1989 • 167 citations

A Bacillus cereus cytolytic determinant, cereolysin AB, which comprises the phospholipase C and sphingomyelinase genes: nucleotide sequence and genetic linkage

1989 • 165 citations

Molecular comparison of a nonhemolytic and a hemolytic phospholipase C from Pseudomonas aeruginosa

1990 • 164 citations

Pseudomonas aeruginosa : clinical manifestations of infection and current therapy

1979 • 159 citations

The Interaction of Clostridium perfringens and Its Toxins in the Production of Necrotic Enteritis of Chickens

1977 • 149 citations

Nucleotide sequence of the gene for perfringolysin O (theta-toxin) from Clostridium perfringens: significant homology with the genes for streptolysin O and pneumolysin

1988 • 126 citations

In Vivo and in Vitro Transcription of the Clostridium pasteurianum Ferredoxin Gene

1986 • 117 citations

Identification of an iron-regulated virulence determinant in Vibrio cholerae, using TnphoA mutagenesis

1990 • 116 citations

Clostridia of Wound Infection

1970 • 110 citations

Cloning and expression of the phospholipase C gene from Clostridium perfringens and Clostridium bifermentans

1989 • 108 citations

Hemolytic and sphingomyelinase activities of Clostridium perfringens alpha-toxin are dependent on a domain homologous to that of an enzyme from the human arachidonic acid pathway

1991 • 103 citations

Toxins of Clostridium perfringens types A, B, C, D and E

1986 • 101 citations

Sensitive assay for detection of toxin-induced damage to the cytoplasmic membrane of human diploid fibroblasts

1975 • 96 citations

Anaerobic Bacteriology. Clinical and Laboratory Practice

1978 • 96 citations

Cloning and sequencing of the Clostridium perfringens enterotoxin gene

1989 • 94 citations

Phospholipase C and haemolytic activities of Clostridium perfringens alpha-toxin cloned in Escherichia coli: sequence and homology with a Baciilus cereus phospholipase C

1989 • 90 citations

Complete nucleotide sequence and genetic organization of the bacteriocinogenic plasmid, pIP404, from Clostridium perfringens

1988 • 89 citations

A new kinetic approach for studying phospholipase C (Clostridium perfringens .alpha. toxin) activity on phospholipid monolayers

1988 • 88 citations

Gene cloning shows the alpha-toxin of Clostridium perfringens to contain both sphingomyelinase and lecithinase activities

1989 • 88 citations

Cloning and sequencing of a Clostridium perfringens sialidase gene

1988 • 84 citations

Nucleotide sequence and expression of a phosphate-regulated gene encoding a secreted hemolysin of Pseudomonas aeruginosa

1986 • 84 citations

Phospholipase C from Clostridium perfringens: Preparation and characterization of homogeneous enzyme

1984 • 83 citations

Characterization of phospholipase C from Pseudomonas aeruginosa as a potent inflammatory agent

1990 • 77 citations

Markedly unbiased codon usage in Bacillus subtilis

1985 • 72 citations

Recent advances in the genetics of the clostridia

1989 • 69 citations

Cloning and sequencing of a phospholipase C gene of Clostridiumperfringens

1989 • 64 citations

NUTRITIONAL REQUIREMENTS OF CLOSTRIDIUM PERFRINGENS PB6K FOR ALPHA TOXIN PRODUCTION

1965 • 63 citations

Contraction of the rat isolated aorta caused by Clostridium perfringens alpha toxin (phospholipase C): evidence for the involvement of arachidonic acid metabolism

1989 • 56 citations

Production of Phospholipase C (Alpha-toxin), Haemolysins and Lethal Toxins by Clostridium perfringens Types A to D

1976 • 52 citations

Properties of Clostridium Perfringens (Welch II) Type-A -Toxin (Phospholipase c) Purified By Electrofocusing

1974 • 51 citations

Anaerobic Bacteriology: Clinical and Laboratory Practice

1978 • 50 citations

Mechanisms of Microbial Pathogenicity

1955 • 47 citations

Excitatory effect of Clostridium perfringens alpha toxin on the rat isolated aorta

1986 • 47 citations

Functional analysis of different sequence elements in the Escherichia coli galactose operon P 2 promoter

1988 • 46 citations

Protein Secretion in Bacilli

1986 • 45 citations

Numerical Taxonomy of Saccharolytic Clostridia, Particularly Clostridium perfringens-Like Strains: Descriptions of Clostridium absonum sp. n. and Clostridium paraperfringens

1973 • 42 citations

Mapping of mRNA encoding endoglucanase A from Clostridium thermocellum

1986 • 42 citations

IN VITRO AGGREGATION OF PLATELETS INDUCED BY ^|^alpha;-TOXIN (PHOSPHOLIPASE C) OF CLOSTRIDIUM PERFRINGENS

1976 • 39 citations

Effect ofClostridium perfringens phospholipase C (alpha-toxin) on the human diploid fibroblast membrane

1974 • 37 citations

Effect of zinc and calcium ions on the production of alpha-toxin and proteases by Clostridium perfringens

1978 • 37 citations

Genetics of Clostridium

1989 • 36 citations

Aggregation of platelets in the mesenteric microcirculation of the rat induced by α- toxin (phospholipase C) of Clostridium perfringens

1978 • 32 citations

Anti-idiotypic antibody-induced protection against Clostridium perfringens type D

1990 • 31 citations

Apparent phosphate retrieval system in Bacillus cereus

1989 • 31 citations

The role of histidine residues in the alpha toxin ofClostridium perfringens

1990 • 27 citations

Monoclonal antibodies against alpha toxin of Clostridium perfringens

1989 • 25 citations

Mechanisms of microbial pathogenicity.

1968 • 24 citations

The role of alpha-toxin of Clostridium perfringens in experimental gas gangrene in guinea pigs.

1972 • 22 citations

Dissociation of various biological activities of Clostridium perfringens alpha toxin by chemical modification

1989 • 19 citations

Monoclonal antibodies against alpha toxin of Clostridium perfringens

1989 • 18 citations

The role of histidine residues in the alpha toxin of

1990 • 2 citations