Protein Secretion in Bacilli

Compilation of published signal sequences

1984 • 784 citations

Extracellular enzyme synthesis in the genus Bacillus

1977 • 663 citations

Complete sequence of the staphylococcal gene encoding protein A. A gene evolved through multiple duplications.

1984 • 571 citations

CRYSTALLINE SURFACE LAYERS ON BACTERIA

1983 • 566 citations

Covalent Binding of Lipid to Protein

1973 • 431 citations

Extracellular enzyme synthesis in the genus Bacillus.

1977 • 399 citations

Cloning, sequencing, and secretion of Bacillusamyloliquefacienssubtillisin inBacillus subtilis

1983 • 357 citations

Mechanisms of protein localization

1983 • 282 citations

Genes for alkaline protease and neutral protease from Bacillus amyloliquefaciens contain a large open reading frame between the regions coding for signal sequence and mature protein

1984 • 282 citations

STRUCTURE, FUNCTION, AND ASSEMBLY OF CELL WALLS OF GRAM-POSITIVE BACTERIA

1983 • 281 citations

Expression from cloned cDNA of cell-surface secreted forms of the glycoprotein of vesicular stomatitis virus in eucaryotic cells

1982 • 266 citations

The Molecular biology of the bacilli

1982 • 266 citations

Cloning of the neutral protease gene of Bacillus subtilis and the use of the cloned gene to create an in vitro-derived deletion mutation

1984 • 257 citations

Molecular cloning of α-amylase gene from Bacillus amyloliquefaciens and its expression in B. subtilis

1982 • 250 citations

Export and secretion of proteins by bacteria

1985 • 244 citations

Translocation of domains of nascent periplasmic proteins across the cytoplasmic membrane is independent of elongation

1983 • 234 citations

Gene for staphylococcal protein A.

1983 • 224 citations

PRODUCTION OF EXTRACELLULAR PROTEINS BY BACTERIA

1976 • 211 citations

Nucleotide sequence of the amylase gene fromBacillus subtilis

1983 • 204 citations

Cloning structural gene sacB, which codes for exoenzyme levansucrase of Bacillus subtilis: expression of the gene in Escherichia coli

1983 • 202 citations

Mechanism of Action of Phenethyl Alcohol: Breakdown of the Cellular Permeability Barrier

1967 • 184 citations

Synthesis of Exported Proteins by Membrane-Bound Polysomes from Escherichia coli

1977 • 177 citations

In vitro translocation of bacterial proteins across the plasma membrane of Escherichia coli.

1984 • 174 citations

Penicillinase from Bacillus licheniformis: nucleotide sequence of the gene and implications for the biosynthesis of a secretory protein in a Gram-positive bacterium

1981 • 160 citations

The DNA sequence of the gene and genetic control sites for the excretedB. subtilis enzymeβglucanase

1984 • 156 citations

Cloning of the genes for penicillinase, penP and penI, of Bacillus licheniformis in some vector plasmids and their expression in Escherichia coli, Bacillus subtilis, and Bacillus licheniformis

1981 • 154 citations

Molecular cloning of a thermostable neutral protease gene from Bacillus stearothermophilus in a vector plasmid and its expression in Bacillus stearothermophilus and Bacillus subtilis

1983 • 153 citations

Secretion of Interferon by Bacillus subtilis

1983 • 150 citations

Cloning and expression of a Bacillus coagulans amylase gene in Escherichia coli

1982 • 148 citations

Characterization of new membrane lipoproteins and their precursors of Escherichia coli.

1981 • 146 citations

The subtilisin E gene of Bacillus subtilis is transcribed from a sigma 37 promoter in vivo.

1984 • 145 citations

Translocation and assembly of outer membrane proteins of Escherichia coli Selective accumulation of precursors and novel assembly intermediates caused by phenethyl alcohol

1979 • 142 citations

Membrane-bound penicillinases in Gram-positive bacteria.

1982 • 142 citations

Pleiotropic mutations affecting sporulation conditions and the syntheses of extracellular enzymes in Bacillus subtilis 168

1975 • 138 citations

Alpha-amylase genes (amyR2 and amyE+) from an alpha-amylase-hyperproducing Bacillus subtilis strain: molecular cloning and nucleotide sequences

1983 • 137 citations

Nucleotide sequence of the promoter and NH2-terminal signal peptide region of the α-amylase gene from Bacillus amyloliquefaciens

1981 • 136 citations

Secretion of Escherichia coli beta-lactamase from Bacillus subtilis by the aid of alpha-amylase signal sequence.

1982 • 131 citations

Structural Studies on the Four Repetitive Fc-Binding Regions in Protein A from Staphylococcus aureus

1977 • 129 citations

Genetics and Biotechnology of Bacilli

1988 • 126 citations

Molecular Cloning and Gene Regulation in Bacilli

1982 • 123 citations

Pleiotropic phenomena in autolytic enzyme(s) content, flagellation, and simultaneous hyperproduction of extracellular alpha-amylase and protease in a Bacillus subtilis mutant

1975 • 102 citations

Mechanisms of protein localization.

1983 • 100 citations

Molecular cloning and expression of a Bacillus subtilis β-glucanase gene in Escherichia coli

1983 • 93 citations

Nucleotide sequence of the staphylokinase gene fromStaphylococcus aurens

1983 • 91 citations

Transcription and translation of foreign genes in Bacillus subtilis by the aid of a secretion vector

1985 • 87 citations

Mapping of mutations affecting synthesis of exocellular enzymes in Bacillus subtilis

1976 • 85 citations

Lipoprotein nature of Bacillus licheniformis membrane penicillinase.

1981 • 85 citations

The complete nucleotide sequence of the xylanase gene (xynA) of Bacillus pumilus

1984 • 82 citations

Molecular cloning of the genes for xylan degradation of Bacillus pumilus and their expression in Escherichia coli

1983 • 74 citations

Cloning and expression of a thermophilic α-amylase gene from Bacillus stearothermophilus in Escherichia coli

1984 • 74 citations

Glyceride-cysteine lipoproteins and secretion by Gram-positive bacteria

1982 • 71 citations

Mutation of Bacillus subtilis causing hyperproduction of alpha-amylase and protease, and its synergistic effect

1975 • 69 citations

Membrane-bound and soluble extracellular alpha-amylase from Bacillus subtilis.

1979 • 62 citations

Interaction of secreted nascent chains with surrounding membrane in Bacillus subtilis.

1978 • 62 citations

Molecular cloning and expression of the xylanase gene of alkalophilic Bacillus sp. strain C-125 in Escherichia coli

1985 • 61 citations

The Industrial Use of Bacilli

1982 • 60 citations

Extracellular and membrane-bound proteases from Bacillus subtilis

1980 • 56 citations

Localization of Polyribosomes Containing Alkaline Phosphatase Nascent Polypeptides on Membranes of Escherichia coli

1974 • 55 citations

Bacterial alpha-amylases.

1978 • 55 citations

Proteins of ribosome-bearing and free-membrane domains in Bacillus subtilis

1983 • 54 citations

Molecular cloning and gene regulation in bacilli

1982 • 53 citations

Molecular cloning and nucleotide sequence of the type I β-lactamase gene fromBacillus cereus

1983 • 53 citations

Large exopenicillinase, initial extracellular form detected in cultures of Bacillus licheniformis

1980 • 49 citations

Characterization of the extracellular lipase of Bacillus subtilis and its relationship to a membrane-bound lipase found in a mutant strain.

1979 • 49 citations

Nucleotide sequence of the 5' region of the Bacillus licheniformis alpha-amylase gene: comparison with the B. amyloliquefaciens gene

1984 • 48 citations

Cloning and expression in Escherichia coli and Bacillus subtilis of the hemolysin (cereolysin) determinant from Bacillus cereus

1983 • 44 citations

Localization and quantitation of proteins characteristic of the complexed membrane of Bacillus subtilis

1983 • 44 citations

Bacterial α-Amylases

1978 • 43 citations

Membrane mutation related to the production of extracellular α-amylase and protease in

1973 • 42 citations

Length and structural effect of signal peptides derived fromBacillus subtilisα-amylase on secretion ofEscherichja coliβ-lactamase in B.subtiliscells

1984 • 42 citations

Synthesis and secretion of biologically active mouse Interferon-β using a Bacillus subtilis α-amylase secretion vector

1985 • 41 citations

Molecular cloning of a major cell wall protein gene from protein-producing Bacillus brevis 47 and its expression in Escherichia coli and Bacillus subtilis

1984 • 39 citations

Identification of the signal peptidase cleavage site in Bacillus licheniformis prepenicillinase.

1982 • 39 citations

Localization in the Cell and Extraction of Alkaline Phosphatase from Bacillus subtilis

1970 • 39 citations

A 64-kilodalton membrane protein of Bacillus subtilis covered by secreting ribosomes.

1983 • 39 citations

Purification and characterization of extracellular soluble and membrane-bound insoluble alkaline phosphatases possessing phosphodiesterase activities in Bacillus subtilis

1978 • 39 citations

The promoter-proximal region of the Bacillus licheniformis penicillinase gene: Nucleotide sequence and predicted leader peptide sequence

1981 • 39 citations

Bacillus licheniformis penicillinase: cleavages and attachment of lipid during cotranslational secretion.

1981 • 38 citations

A Bacillus subtilis Secretion Vector System Derived from the B. subtilis α-Amylase Promoter and Signal Sequence Region, and Secretion of Escherichia coli β-Lactamase by the Vector System 1

1984 • 38 citations

Molecular Cloning and Expression of Penicillinase Genes from Bacillus licheniformis in the Thermophile Bacillus stearothermophilus

1982 • 36 citations

Construction of penP delta 1, Bacillus licheniformis 749/C beta-lactamase lacking site for lipoprotein modification. Expression in Escherichia coli and Bacillus subtilis.

1983 • 35 citations

Extracellular labeling of growing secreted polypeptide chains in Bacillus subtilis with diazoiodosulfanilic acid

1979 • 35 citations

Alkaline phosphatase possessing alkaline phosphodiesterase activity and other phosphodiesterases in Bacillus subtilis

1978 • 33 citations

Genetic and Biochemical Studies on Cell-Bound α-Amylase in Bacillus subtilis Marburg

1974 • 33 citations

Effect of cobalt on synthesis and activation of Bacillus licheniformis alkaline phosphatase

1981 • 32 citations

Affinity chromatography purification of penicillinase of Bacillus licheniformis 749/C and its use to measure turnover of the cell bound enzyme

1973 • 32 citations

Export of extracellular levansucrase by Bacillus subtilis: inhibition by cerulenin and quinacrine

1979 • 31 citations

The 64-kilodalton membrane protein of Bacillus subtilis is also present as a multiprotein complex on membrane-free ribosomes.

1984 • 29 citations

Cloning of a thermostable α-amylase gene fromBacillus licheniformisand its expression inEscherichia coliandBacillus subtilis

1984 • 29 citations

Preferential suppression of normal exoenzyme formation by membrane-modifying agents

1980 • 28 citations

Synthesis of OmpA Protein of Escherichia coli K12 in Bacillus subtilis

1986 • 27 citations

Biochemical localization of the alkaline phosphatase of Bacillus licheniformis as a function of culture age

1977 • 26 citations

Extreme Sensitivity of Staphylococcal Enterotoxin B and C Production to Inhibition by Cerulenin

1977 • 25 citations

Subcellular localization of alkaline phosphatase in Bacillus licheniformis 749/C by immunoelectron microscopy with colloidal gold

1984 • 25 citations

Characterization of the precursor form of the exocellular levansucrase from Bacillus subtilis

1984 • 25 citations

Levansucrase of Bacillus subtilis: Conclusive Evidence that Its Production and Export are Unrelated to Fatty-Acid Synthesis but Modulated by membrane-Modifying Agents

1981 • 25 citations

Isolation and the 5'-end nucleotide sequence of Bacillus licheniformis alpha-amylase gene

1984 • 25 citations

Vesicle penicillinase of Bacillus licheniformis: existence of periplasmic-releasing factor(s)

1977 • 24 citations

Comparative Studies on Extracellular Penicillinases of the Same Structural Gene, penP, Expressed in Bacillus licheniformis and Bacillus subtilis

1983 • 24 citations

Growth Defects Of Escherichia Coli Cells Which Contain The Gene Of An -Amylase from Bacillus coagulans on a Multicopy Plasmid

1983 • 23 citations

Nucleotide sequence of the promotor and NH2-terminal signal peptide region of Bacillussubtilis α-amylase gene cloned in pUB110

1983 • 23 citations

Evidence linking penicillinase formation and secretion to lipid metabolism in Bacillus licheniformis

1978 • 23 citations

Comparison of levansucrase fromBacillus subtilisand fromBacillus amyloliquefaciens

1982 • 21 citations

The inhibition ofStaphylococcus aureusenterotoxin a production by cerulenin and quinacrine; presumptive evidence for a lipid intermediate/protease release mechanism

1987 • 17 citations

Purification and Characterization of an Extracellular and a Cellular -Glucosidase from Bacillus licheniformis

1984 • 17 citations

Cloning and expression in Escherichia coli of the regulatory sacU gene from Bacillus subtilis

1985 • 17 citations

Membrane-associated alkaline phosphatase from Bacillus licheniformis that requires detergent for solubilization: lactoperoxidase 125I localization and molecular weight determination

1982 • 16 citations

Synthesis of α-amylase and α-glucosidase by membrane bound ribosomes from Bacilluslicheniformis

1983 • 15 citations

Cerulenin Inhibits Production of Extracellular Proteins but not Membrane Proteins in Bacillus amyloliquefaciens

1980 • 15 citations

Detection of a Membrane-associated Protein on Detached Membrane Ribosomes in Staphylococcus aureus

1984 • 14 citations

Immunological cross-reaction between proteins supposed to be involved in protein secretion inStaphylococcus aureusandBacillus subtilis

1984 • 14 citations

Levansucrase of Bacillus subtilis

1980 • 14 citations

A soluble alkaline phosphatase from Bacillus licheniformis MC14. Histochemical localization, purification, characterization and comparison with the membrane-associated alkaline phosphatase

1981 • 14 citations

Cloning and characterization of the Bacillus licheniformis gene coding for alkaline phosphatase

1984 • 14 citations

Secretion of Semliki Forest virus membrane glycoprotein El from Bacillus subtilis

1985 • 13 citations

Expression of the vesicular stomatitis virus membrane glycoprotein gene inBacillus subtilis

1984 • 13 citations

The inhibition ofStaphylococcus aureusenterotoxin a production by cerulenin and quinacrine; presumptive evidence for a lipid intermediate/protease release mechanism

1978 • 13 citations

β-LACTAMASES OF BACILLI: NATURE AND PROCESSING

1984 • 12 citations

Host—vector systems in thermophilic Bacilli and their applications

1983 • 12 citations

Alkaline phosphatase secretion-negative mutant of Bacillus licheniformis 749/C

1983 • 11 citations

Translational control ofOmpF, OmpCandLamBgenetic expression during lipid synthesis inhibition ofEscherichia coli

1982 • 7 citations

THE SUCROSE SYSTEM AS A MODEL OF GENETIC REGULATION IN BACILLUS SUBTILIS

1984 • 6 citations

Specificity of subcellular distribution of alkaline phosphatase in Bacillus licheniformis 749/C

1984 • 6 citations

SECRETION OF FOREIGN GENE PRODUCTS BY THE AID OF A BACILLUS SECRETION VECTOR

1984 • 6 citations

Isolation of a mutant secreting extracellular soluble alkaline phosphatase in Bacillus subtilis.

1976 • 6 citations

Independent control of the production and localization of alkaline phosphatase from the production of .ALPHA.-amylase and protease in Bacillus subtilis.

1978 • 4 citations

Penicillinase and the Secretion of Proteins by Bacilli11Supported by grants from the National Institute of Health (AI-04572), Miles Laboratories, Inc., and the Charles and Johanna Busch Memorial Fund.

1982 • 3 citations

Deleted Work

1955 • 0 citations