Induction of iNOS in a rat model of acute colitis.

Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

1982 • 11,668 citations

Nitric oxide synthases in mammals

1994 • 2,762 citations

Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon

1989 • 1,681 citations

Experimental models of inflammatory bowel disease

1995 • 1,215 citations

Nitrite and nitrate determinations in plasma: a critical evaluation

1995 • 1,095 citations

1400W Is a Slow, Tight Binding, and Highly Selective Inhibitor of Inducible Nitric-oxide Synthase in Vitro and in Vivo

1997 • 828 citations

Widespread tissue distribution, species distribution and changes in activity of Ca²⁺‐dependent and Ca²⁺‐independent nitric oxide synthases

1991 • 645 citations

Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease

1996 • 588 citations

Nitric oxide synthase activity in ulcerative colitis and Crohn's disease

1993 • 468 citations

Inflammatory Bowel Disease

1996 • 398 citations

Superinduction of cyclooxygenase-2 activity in human osteoarthritis-affected cartilage. Influence of nitric oxide.

1997 • 381 citations

Enhanced colonic nitric oxide generation and nitric oxide synthase activity in ulcerative colitis and Crohn's disease.

1995 • 363 citations

Evidence of oxidant-induced injury to epithelial cells during inflammatory bowel disease.

1996 • 349 citations

Co‐induction of nitric oxide synthase and cyclo‐oxygenase: interactions between nitric oxide and prostanoids

1995 • 343 citations

The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat

1993 • 295 citations

Greatly increased luminal nitric oxide in ulcerative colitis

1994 • 268 citations

A comparative analysis of two models of colitis in rats

1992 • 265 citations

Inducible nitric oxide synthase plays a critical role in resolving intestinal inflammation

1997 • 252 citations

Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells

1993 • 248 citations

Nitric Oxide Produced by Endothelial Cells Increases Production of Eicosanoids Through Activation of Prostaglandin H Synthase

1995 • 239 citations

Experimental colitis is ameliorated by inhibition of nitric oxide synthase activity.

1995 • 191 citations

The selective beneficial effects of nitric oxide inhibition in experimental colitis

1995 • 169 citations

Experimental Colitis in Animal Models

1992 • 169 citations

Nitric oxide-mediated cyclooxygenase activation. A key event in the antiplatelet effects of nitrovasodilators.

1996 • 169 citations

Induction of nitric oxide synthase in rat peritoneal neutrophils and its inhibition by dexamethasone

1991 • 161 citations

Increased nitric oxide production and inducible nitric oxide synthase activity in colonic mucosa of patients with active ulcerative colitis and Crohn's disease.

1997 • 157 citations

Effects of Chronic Nitric Oxide Synthase Inhibition on TNB-induced Colitis in Rats

1995 • 87 citations

Nitric oxide enhances prostaglandin-H synthase-1 activity by a heme-independent mechanism: Evidence implicating nitrosothiols

1995 • 83 citations

Induction of Nitric Oxide Synthase and Concomitant Suppression of Superoxide Dismutases in Experimental Colitis in Rats

1995 • 80 citations

Distribution of inducible nitric oxide synthase in ulcerative colitis.

1997 • 78 citations

Expression of nitric oxide synthase in ulcerative colitis

1996 • 76 citations

INTERLEUKIN-8 AND INDUCIBLE NITRIC OXIDE SYNTHASE mRNA LEVELS IN INFLAMMATORY BOWEL DISEASE AT FIRST PRESENTATION

1997 • 67 citations

Sulfhydryl blocker-induced rat colonic inflammation is ameliorated by inhibition of nitric oxide synthase

1995 • 60 citations

Time-dependent actions of nitric oxide synthase inhibition on colonic inflammation induced by trinitrobenzene sulphonic acid in rats

1997 • 55 citations

The effect of inhibitors of inducible nitric oxide synthase on chronic colitis in the rhesus monkey.

1997 • 53 citations

Inhibition by nitric oxide‐releasing compounds of prostacyclin production in human endothelial cells

1998 • 50 citations

Induction of nitric oxide synthase in rat intestine and its association with tissue injury

1993 • 39 citations

Manipulation of the <scp>l</scp>-arginine-nitric oxide pathway in experimental colitis

1995 • 27 citations

Is nitric oxide and heparin treatment justified in inflammatory bowel disease? An experimental study

1996 • 26 citations

Persistent induction of nitric oxide synthase in tumours from mice treated with the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid

1998 • 21 citations

Intracolonic release of nitric oxide during trinitrobenzene sulfonic acid rat colitis.

1997 • 19 citations

Colonic microvascular integrity in acute endotoxaemia: interactions between constitutive nitric oxide and 5-lipoxygenase products

1995 • 18 citations

Prostaglandin E2 adn gestational hypotension in rabbits

1990 • 13 citations

Efffects of NO-Donors, SIN-1 and GEA 3175 on Prostacyclin and cGMP Synthesis in Cultured Rat Endothelial Cells

1995 • 7 citations