Glutamate-Dopamine Balance in the Striatum: Pre- and Post-Synaptic Interactions

Multiple receptors for dopamine

1979 • 3,739 citations

D ₁ and D ₂ Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons

1990 • 2,873 citations

Brain dopamine and the syndromes of Parkinson and Huntington Clinical, morphological and neurochemical correlations

1973 • 2,615 citations

Physiologic Dysfunction of Dorsolateral Prefrontal Cortex in Schizophrenia

1986 • 2,026 citations

Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: A hypothesis for the etiology of schizophrenia

1991 • 1,819 citations

Ascending Monoamine Neurons to the Telencephalon and Diencephalon

1966 • 1,205 citations

The release of neural transmitter substances

1969 • 1,134 citations

Interactions between glutamatergic and monoaminergic systems within the basal ganglia-implications for schizophrenia and Parkinson's disease

1990 • 1,102 citations

The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones

1990 • 1,021 citations

Calcium Action in Synaptic Transmitter Release

1987 • 742 citations

Dendritic release of dopamine in the substantia nigra

1981 • 732 citations

Dopamine Receptor Binding Enhancement Accompanies Lesion-Induced Behavioral Supersensitivity

1977 • 716 citations

Low cerebrospinal fluid glutamate in schizophrenic patients and a new hypothesis on schizophrenia

1980 • 703 citations

Typical and atypical neuroleptics: differential effects of chronic administration on the activity of A9 and A10 midbrain dopaminergic neurons

1983 • 680 citations

Extrinsic connections of the basal ganglia

1990 • 609 citations

Presynaptic regulation of neurotransmitter release in the brain: Facts and hypothesis

1984 • 576 citations

Acute and chronic haloperidol treatment: Comparison of effects on nigral dopaminergic cell activity

1978 • 550 citations

Biochemical evidence for glutamate as neurotransmitter in corticostriatal and corticothalamic fibres in rat brain

1981 • 547 citations

A glutamatergic corticostriatal path?

1977 • 487 citations

Phenotypical characterization of the rat striatal neurons expressing the D1 dopamine receptor gene.

1991 • 477 citations

Dopamine receptor gene expression by enkephalin neurons in rat forebrain.

1990 • 469 citations

Chemical and structural analysis of the relation between cortical inputs and tyrosine hydroxylase-containing terminals in rat neostriatum

1984 • 467 citations

New roles for glia

1991 • 464 citations

Trans-striatal dialysis coupled to reverse phase high performance liquid chromatography with electrochemical detection: a new method for the study of the in vivo release of endogenous dopamine and metabolites

1984 • 454 citations

Input from the frontal cortex and the parafascicular nucleus to cholinergic interneurons in the dorsal striatum of the rat

1992 • 444 citations

Tonic Activation of NMDA Receptors by Ambient Glutamate Enhances Excitability of Neurons

1989 • 434 citations

Dopamine receptors localised on cerebral cortical afferents to rat corpus striatum

1978 • 401 citations

The precise localization of nigral afferents in the rat as determined by a retrograde tracing technique

1976 • 374 citations

Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia

1985 • 373 citations

The NMDA Receptor

1995 • 356 citations

Tonic Activation of NMDA Receptors Causes Spontaneous Burst Discharge of Rat Midbrain Dopamine Neurons In Vivo

1993 • 350 citations

Excitatory influence of rat subthalamic nucleus to substantia nigra pars reticulata and the pallidal complex: electrophysiological data

1990 • 343 citations

Ultrastructural immunocytochemical localization of tyrosine hydroxylase in the neostriatum

1981 • 332 citations

Synthesis and release of neuroactive substances by glial cells

1992 • 327 citations

Glutamatergic Control of Dopamine Release in the Rat Striatum: Evidence for Presynaptic N‐Methyl‐D‐Aspartate Receptors on Dopaminergic Nerve Terminals

1991 • 324 citations

Release of dopamine in vivo from cat substantia nigra

1977 • 318 citations

Regulation of dopamine release by impulse flow and by autoreceptors as studied by in vivo voltammetry in the rat striatum

1985 • 317 citations

Relationship between dopamine release in the rat nucleus accumbens and the discharge activity of dopaminergic neurons during local in vivo application of amino acids in the ventral tegmental area

1992 • 315 citations

STIMULATORY EFFECT OF <scp>l</scp>‐GLUTAMATE AND RELATED AMINO ACIDS ON [³H]DOPAMINE RELEASE FROM RAT STRIATUM: AN IN VITRO MODEL FOR GLUTAMATE ACTIONS

1979 • 315 citations

Deficits in Feeding Behavior after Intraventricular Injection of 6-Hydroxydopamine in Rats

1972 • 296 citations

In vivo presynaptic control of dopamine release in the cat caudate nucleus—II. Facilitatory or inhibitory influence ofl-glutamate

1986 • 290 citations

Burst firing induced in midbrain dopamine neurons by stimulation of the medial prefrontal and anterior cingulate cortices

1988 • 281 citations

MONITORING MOLECULES IN NEUROSCIENCE

1991 • 272 citations

Dopamine release in the nucleus caudatus and in the nucleus accumbens is under glutamatergic control through non-NMDA receptors: a study in freely-moving rats

1990 • 260 citations

Direct in Vivo Monitoring of Dopamine Released from Two Striatal Compartments in the Rat

1983 • 260 citations

Immunohistochemical localization of the D1 dopamine receptor in rat brain reveals its axonal transport, pre- and postsynaptic localization, and prevalence in the basal ganglia, limbic system, and thalamic reticular nucleus.

1992 • 258 citations

Characterization of L-glutamate action on the release of endogenous dopamine from the rat caudate-putamen.

1989 • 242 citations

Regional Brain Glucose Metabolism in Chronic Schizophrenia

1984 • 237 citations

Role of the subthalamic nucleus in the regulation of nigral dopamine neuron activity

1992 • 231 citations

Release-regulating D-2 dopamine receptors are located on striatal glutamatergic nerve terminals.

1988 • 229 citations

Dopaminergic Modulation of Glutamate Release in Striatum as Measured by Microdialysis

1992 • 225 citations

Iontophoretically administered drugs acting at the N‐methyl‐D‐aspartate receptor modulate burst firing in A9 dopamine neurons in the rat

1992 • 219 citations

Comparison of the effects of chronic haloperidol treatment on A9 and A10 dopamine neurons in the rat

1983 • 212 citations

Dopamine receptors: Pharmacological and anatomical evidences indicate that two distinct dopamine receptor populations are present in rat striatum

1978 • 203 citations

Release of dopamine evoked by electrical stimulation of the motor and visual areas of the cerebral cortex in both caudate nuclei and in the substantia nigra in the cat

1978 • 202 citations

The synaptic organization of the caudate nucleus

1971 • 199 citations

A morphometric study of the dopamine-containing cell groups in the mesencephalon of normals, Parkinson patients, and schizophrenics.

1983 • 197 citations

Activation of dopamine receptors inhibits calcium-dependent glutamate release from cotico-striatal terminals in vitro

1980 • 189 citations

Presynaptic Glutamate Receptors Modulate Dopamine Release from Striatal Synaptosomes

1991 • 188 citations

Presynaptic dopaminergic modulation of cortical input to the striatum

1986 • 184 citations

Glutamate release in vitro from corticostriatal terminals

1979 • 179 citations

The glutamate-mediated release of dopamine in the rat striatum: Further characterization of the dual excitatory-inhibitory function

1990 • 179 citations

Effect ofl-glutamate on the release of striatal dopamine: in vivo dialysis and electrochemical studies

1990 • 176 citations

Differential Control by N‐Methyl‐D‐Aspartate and Kainate of Striatal Dopamine Release In Vivo: A Trans‐Striatal Dialysis Study

1988 • 175 citations

Topographical distribution of possible glutamatergic pathways from the frontal cortex to the striatum and substantia nigra in rats

1982 • 171 citations

Modulation of striatal [3H]-glutamic acid release by dopaminergic drugs

1980 • 169 citations

Anticataleptic effects of the N-methyl-D-aspartate antagonist MK-801 in rats

1989 • 168 citations

l-Glutamate-evoked release of dopamine from synaptosomes of the rat striatum: Involvement of AMPA and N-methyl-d-aspartate receptors

1992 • 166 citations

Quantitative autoradiography of dopamine D2 sites in rat caudate-putamen: Localization to intrinsic neurons and not to neocortical afferents

1987 • 165 citations

Bilateral regulation of glutamate tissue and extracellular levels in caudate-putamen by midbrain dopamine neurons

1990 • 158 citations

On the mode of action of apomorphine

1973 • 152 citations

A microiontophoretic study on the nature of the putative synaptic neurotransmitter involved in the pedunculopontine-substantia nigra pars compacta excitatory pathway of the rat

1986 • 151 citations

Glutamate receptor subtypes mediate excitatory synaptic currents of dopamine neurons in midbrain slices

1991 • 145 citations

Monitoring the Stimulated Release of Dopamine with In Vivo Voltammetry. I: Characterization of the Response Observed in the Caudate Nucleus of the Rat

1984 • 143 citations

Increased dopamine efflux from striatal slices during development and after nigrostriatal bundle damage

1987 • 143 citations

Complete Conversion of Brain D₂ Dopamine Receptors from the High‐ to the Low‐Affinity State for Dopamine Agonists, Using Sodium Ions and Guanine Nucleotide

1985 • 139 citations

The electrophysiology of dopamine (D2) receptors: A study of the actions of dopamine on corticostriatal transmission

1983 • 137 citations

Effects ofl-glutamate and related amino acids upon the release of [3H]dopamine from rat striatal slices

1978 • 135 citations

The cortico-nigral projection: reduced glutamate content in the substantia nigra following frontal cortex ablation in the rat

1984 • 133 citations

Effects of intraventricular 6-hydroxydopamine on the dopaminergic innervation of striatum: Histochemical and neurochemical analysis

1986 • 131 citations

Differentiation of Dopamine Overflow and Uptake Processes in the Extracellular Fluid of the Rat Caudate Nucleus with Fast-Scan In Vivo Voltammetry

1988 • 129 citations

Regional release of [³H]dopamine from rat brain in vitro: effects of opioids on release induced by potassium, nicotine, and <scp>L</scp>-glutamic acid

1983 • 127 citations

Non-synaptic interactions at presynaptic level

1991 • 126 citations

The release of dopamine from nerve terminals and dendrites of nigrostriatal neurons induced by excitatory amino acids in the conscious rat

1992 • 125 citations

Extracellular dopamine in striatum: Influence of nerve impulse activity in medial forebrain bundle and local glutamatergic input

1992 • 123 citations

Low HVA and normal 5HIAA CSF levels in drug-free schizophrenic patients compared to healthy volunteers: Correlations to symptomatology and family history

1985 • 121 citations

Glutamate‐evoked release of endogenous brain dopamine: inhibition by an excitatory amino acid antagonist and an enkephalin analogue

1987 • 110 citations

The effects of dopamine-depleting brain lesions on the electrophysiological activity of rat substantia nigra dopamine neurons

1990 • 109 citations

Terminal excitability of the corticostriatal pathway. II. Regulation by glutamate receptor stimulation

1991 • 102 citations

Compensatory Increase in Tyrosine Hydroxylase Activity in Rat Brain After Intraventricular Injections of 6-Hydroxydopamine

1980 • 102 citations

Localization of D-2 dopamine receptors to intrinsic striatal neurones by quantitative autoradiography

1986 • 102 citations

The distribution of a dopamine D2 receptor mRNA in rat brain

1989 • 101 citations

Glutamate: a new target in schizophrenia?

1990 • 98 citations

High glutamate concentrations evoke Ca(++)-independent dopamine release from striatal slices: a possible role of reverse dopamine transport.

1991 • 97 citations

Localization of striatal excitatory amino acid binding site subtypes to striatonigral projection neurons

1992 • 88 citations

Dopaminergic neurons: simultaneous measurements of dopamine release and single-unit activity during stimulation of the medial forebrain bundle

1987 • 83 citations

NMDA receptor mediates dopamine release in the striatum of unanesthetized rats as measured by brain microdialysis

1992 • 82 citations

GABA axons in synaptic contact with dopamine neurons in the substantia nigra: double immunocytochemistry with biotin-peroxidase and protein A-colloidal gold

1985 • 79 citations

Role of presynaptic dopamine receptors in regulation of the glutamatergic neurotransmission in rat neostriatum

1984 • 79 citations

Terminal excitability of the corticostrial pathway. I. Regulation by dopamine receptor stimulation

1991 • 74 citations

Localization of nigrostriatal dopamine receptor subtypes and adenylate cyclase

1988 • 72 citations

Modulation of Dendritic Release of Dopamine by N‐Methyl‐D‐Aspartate Receptors in Rat Substantia Nigra

1989 • 72 citations

Glutamate Receptors of a Quisqualate‐Kainate Subtype are Involved in the Presynaptic Regulation of Dopamine Release in the Cat Caudate Nucleus in vivo

1990 • 70 citations

Kainic acid lesions of striatum and decortication reduce specific [3H]sulpiride binding in rats, so D-2 receptors exist post-synaptically on corticostriate afferents and striatal neurons

1981 • 69 citations

The Basal Ganglia III

1991 • 67 citations

Intracellular studies of dopamine neurons in vitro: pacemakers modulated by dopamine

1988 • 66 citations

Branched output neurons of the rat subthalamic nucleus: Electrophysiological study of the synaptic effects on identified cells in the two main target nuclei, the entopeduncular nucleus and the substantia nigra

1983 • 64 citations

Extrinsic Connections of the Neostriatum

1979 • 62 citations

Synaptic endings and their postsynaptic targets in neostriatum: synaptic specializations revealed from analysis of serial sections.

1980 • 61 citations

Continuous glutamate leakage from brain cells is balanced by compensatory high-affinity reuptake transport

1987 • 58 citations

Behavioural, pharmacological and biochemical effects of acute and chronic administration of ketamine in the rat

1991 • 52 citations

The cortico‐nigral projection in the cat an experimental study with silver impregnation methods

1966 • 52 citations

In vivo presynaptic control of dopamine release in the cat caudate nucleus—I. Opposite changes in neuronal activity and release evoked from thalamic motor nuclei

1986 • 52 citations

Pharmacological evidence for N-methyl-<scp>D</scp>-aspartate receptors on nigrostriatal dopaminergic nerve terminals

1991 • 49 citations

Inhibitory effects of dopamine on high affinity glutamate uptake from rat striatum

1982 • 48 citations

Chronic administration of NMDA antagonists induces D2 receptor synthesis in rat striatum

1992 • 47 citations

Activation of receptors contributes to the EPSP at perforant path synapses in the rat dentate gyrus in vitro

1989 • 46 citations

An afterhyperpolarization recorded in striatal cells ?in vitro?: effect of dopamine administration

1988 • 46 citations

The cortico-nigral fibre tract. An experimental Fink-Heimer study in cats.

1974 • 42 citations

Topographic changes in high-affinity glutamate uptake in the cat red nucleus, substantia nigra, thalamus, and caudate nucleus after lesions of sensorimotor cortical areas

1983 • 42 citations

l-Glutamic acid, a neuromodulator of dopaminergic transmission in the rat corpus striatum☆

1983 • 38 citations

Changes in choline acetyltransferase, glutamic acid decarboxylase, high-affinity glutamate uptake and dopaminergic activity induced by kainic acid lesion of the thalamostriatal neurons

1985 • 37 citations

Do nigro-striatal neurones possess a discrete dendritic modulatory mechanism? Electrophysiological evidence from the actions of amphetamine in brain slices

1988 • 36 citations

Subtypes of excitatory amino acid receptors involved in the stimulation of [³H]dopamine release from cell cultures of rat ventral mesencephalon

1990 • 33 citations

Repeated atypical neuroleptic administration: effects on central dopamine metabolism monitored by in vivo voltammetry

1987 • 28 citations

Axo-Axonic Synapses in the Rat Striatum

1983 • 27 citations

Effects of an N-methyl-d-aspartate receptor agonist and its antagonist CPP on the levels of dopamine and serotonin metabolites in rat striatum collected in vivo by using a brain dialysis technique

1989 • 25 citations

A quantitative description of excitatory amino acid neurotransmitter responses on cultured embryonic Xenopus spinal neurons

1989 • 24 citations

Increased midbrain dopaminergic cell activity following 2′CH3-MPTP-induced dopaminergic cell loss: an in vitro electrophysiological study

1990 • 23 citations

Induction of D2 dopamine receptor mRNA synthesis in a 6-hydroxydopamine Parkinsonian rat model

1992 • 22 citations

Partial characterization of kainic acid-induced striatal dopamine release using in vivo microdialysis

1991 • 19 citations

Supersensitivity of presynaptic receptors involved in the dopaminergic control of striatal high affinity glutamate uptake after 6-hydroxydopamine lesion of nigrostriatal dopaminergic neurons

1988 • 14 citations

Dopaminergic binding sites in rat striatal slices and the action of guanyl nucleotides

1984 • 14 citations

Characterization of the Synaptic Inputs to Dopaminergic Neurones in the Rat Substantia Nigra

1991 • 10 citations

Influence of Cortico-Striatal Glutamatergic Neurons on Dopaminergic Transmission in the Striatum

1991 • 5 citations

Reply to the letter to the editor by Kilpatrick and Phillipson

1986 • 3 citations