Polyamines, DNA Methylation and Cell Differentiation

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

DNA Methylation and Gene Function

1980 • 2,069 citations

Polyamine metabolism and its importance in neoplastic growth and a target for chemotherapy.

1988 • 1,533 citations

DNA METHYLATION AND GENE ACTIVITY

1983 • 1,115 citations

Catalytic irreversible inhibition of mammalian ornithine decarboxylase (E.C.4.1.1.17) by substrate and product analogs

1978 • 998 citations

Role of Polyamines in the Control of Cell Proliferation and Differentiation

1981 • 935 citations

DNA methylation and the regulation of globin gene expression

1983 • 451 citations

The Specificity of S-Adenosylmethionine Derivatives in Methyl Transfer Reactions

1969 • 281 citations

Accumulation of Decarboxylated S‐Adenosyl‐<scp>l</scp>‐Methionine in Mammalian Cells as a Consequence of the Inhibition of Putrescine Biosynthesis

1982 • 90 citations

Induction of alpha-fetoprotein synthesis in differentiating F9 teratocarcinoma cells is accompanied by a genome-wide loss of DNA methylation.

1984 • 85 citations

DNA Methylation in Eukaryotic Cells

1984 • 81 citations

Effect of inhibition of polyamine synthesis on the content of decarboxylated S-adenosylmethionine

1982 • 74 citations

Purification of human DNA (cytosine-5-)-methyltransferase

1985 • 51 citations

Mammalian DNA methyltransferases prefer poly(dI-dC) as substrate.

1986 • 50 citations

Inhibition of ornithine decarboxylase induces embryonal carcinoma cell differentiation

1983 • 48 citations

Comparison of S-adenosylmethionine decarboxylases from rat liver and muscle

1982 • 47 citations

Studies on Substrate Specificity of S-Adenosylmethionine: Protein-Carboxyl Methyltransferase from Calf Brain

1980 • 47 citations

Human DNA (cytosme-5)methyftransferase selectively methylates duplex DNA containing mispairs

1987 • 45 citations

Effect on prostatic growth of 2-difluoromethylornithine, an effective inhibitor of ornithine decarboxylase

1982 • 32 citations

Acetylation of decarboxylated S-adenosylmethionine by mammalian cells

1986 • 32 citations

Induction of F9 embryonal carcinoma cell differentiation by inhibition of polyamine synthesis.

1985 • 25 citations

Polyamine Synthesis Inhibitors Act as both Inducers and Suppressors of Cell Differentiation

1987 • 24 citations

Polyamine depletion increases cellular ribonucleotide levels

1986 • 17 citations

Size of the directing moiety at carbon 5 of cytosine and the activity of human DNA(cytosine-5)methyltransferase

1987 • 15 citations

[11] Methods for the preparation and assay of S-adenosyl-(5′)-3-methylthiopropylamine (decarboxylated adenosylmethionine)

1983 • 1 citations