Detection of leukemic clone maturation in vivo by premature chromosome condensation

A RAPID BANDING TECHNIQUE FOR HUMAN CHROMOSOMES

1971 • 5,049 citations

Hereditary cancer, oncogenes, and antioncogenes.

1985 • 1,261 citations

Cellular Oncogenes and Multistep Carcinogenesis

1983 • 1,154 citations

Chronic myelocytic leukemia: Clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage

1977 • 888 citations

Single-step separation of red blood cells, granulocytes and mononuclear leukocytes on discontinuous density gradients of Ficoll-Hypaque

1974 • 735 citations

Mammalian Cell Fusion : Induction of Premature Chromosome Condensation in Interphase Nuclei

1970 • 699 citations

Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia

1978 • 593 citations

Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications

1983 • 585 citations

Chronic Myelocytic Leukemia

1978 • 332 citations

Evidence for a multistep pathogenesis of chronic myelogenous leukemia

1981 • 331 citations

Differentiation of Leukemia Cells to Polymorphonuclear Leukocytes in Patients with Acute Nonlymphocytic Leukemia

1986 • 298 citations

Chronic myelogenous leukemia: recent advances

1985 • 247 citations

Acute myelogenous leukemia: recent advances in therapy

1987 • 219 citations

Small doses of ARA‐C in the treatment of acute myeloid leukaemia: differentiation of myeloid leukaemia cells?

1982 • 189 citations

Clinical Implications of Cytogenetic Variants in Chronic Myelocytic Leukemia (CML)

1968 • 184 citations

Does treatment with ARA-C in low dosage cause differentiation of leukemic cells?

1983 • 175 citations

Fundamentals of Chemotherapy of Myeloid Leukemia by Induction of Leukemia Cell Differentiation

1983 • 161 citations

Cell differentiation and bypassing of genetic defects in the suppression of malignancy.

1987 • 118 citations

Induced cell differentiation in cancer therapy.

1984 • 112 citations

Potential pre-screening for therapeutic agents that induce differentiation in human myeloid leukemia cells

1980 • 102 citations

Monosomy 7 in Granulocytes and Monocytes in Myelodysplastic Syndrome

1987 • 99 citations

Preliminary Observations on the Therapy of the Myeloid Blast Phase of Chronic Granulocytic Leukemia with Plicamycin and Hydroxyurea

1986 • 94 citations

Characterization of Glass Adherent Human Mononuclear Cells

1973 • 94 citations

Acute lymphoblastic leukemia in adults: recent progress, future directions.

1987 • 88 citations

3 Prognostic Significance of Chromosomal Abnormalities in Acute Leukaemias and Myelodysplastic Syndromes

1986 • 78 citations

Prolongation of survival time of mice inoculated with myeloid leukemia cells by inducers of normal differentiation.

1979 • 72 citations

A method for simultaneous study of the karyotype, morphology, and immunologic phenotype of mitotic cells in hematologic malignancies

1984 • 71 citations

The myelodysplastic syndrome—a practical guide

1987 • 67 citations

Double minutes replicate once during S phase of the cell cycle

1980 • 65 citations

Cytogenetic evolution and clonal proliferation in acute transformation of chronic granulocytic leukaemia

1968 • 60 citations

Function of Neutrophils in Preleukaemia

1977 • 48 citations

Chronic myelogenous leukemia: amplification of a rearranged c-abl oncogene in both chronic phase and blast crisis

1987 • 44 citations

CT banding of human chromosomes

1976 • 30 citations

Treatment for Myelodysplastic Syndromes

1987 • 29 citations

Improvements in the premature chromosome condensation technique for cytogenetic analysis

1988 • 20 citations

Low‐dose cytosine arabinoside regimen induced a complete remission with normal karyotypes in a case with hypoplastic acute myeloid leukaemia with No. 8‐trisomy: in vitro and in vivo evidence for normal haematopoietic recovery

1985 • 18 citations

Loss of suppression of normal bone marrow colony formation by leukemic cell lines after differentiation is induced by chemical agents

1985 • 17 citations

Induction of differentiation in human myeloid leukemia cells with cytosine arabinoside

1986 • 16 citations

Differentiation versus cytoreduction during remission induction in acute nonlymphoblastic leukemia treated with sequential high-dose ara-C and asparaginase

1984 • 15 citations

Studies on abnormal polymorphonuclear neutrophils in acute myelogenous leukemia: Clinical significance and changes after chemotherapy

1983 • 14 citations