Acute myelogenous leukemia: recent advances in therapy

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

1978 • 1,624 citations

The Will Rogers Phenomenon

1985 • 1,512 citations

Methotrexate and Cyclosporine Compared with Cyclosporine Alone for Prophylaxis of Acute Graft versus Host Disease after Marrow Transplantation for Leukemia

1986 • 1,453 citations

Antileukemic Effect of Chronic Graft-versus-Host Disease

1981 • 1,112 citations

Marrow Transplantation from Related Donors Other Than HLA-Identical Siblings

1985 • 844 citations

Marrow Transplantation for Acute Nonlymphocytic Leukemia after Treatment with Busulfan and Cyclophosphamide

1983 • 831 citations

Immunologic classification of leukemia and lymphoma.

1986 • 773 citations

Criteria for the Diagnosis of Acute Leukemia of Megakaryocyte Lineage (M7)

1985 • 752 citations

Marrow Transplantation for Acute Nonlymphoblastic Leukemia in First Remission

1979 • 655 citations

Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications

1983 • 585 citations

Arabinosyl Cytosine: A Useful Agent in the Treatment of Acute Leukemia in Adults

1968 • 559 citations

Cytomegalovirus Immune Globulin and Seronegative Blood Products to Prevent Primary Cytomegalovirus Infection after Marrow Transplantation

1986 • 528 citations

Cytosine arabinoside with daunorubicin or adriamycin for therapy of acute myelocytic leukemia: a CALGB study

1982 • 521 citations

Autologous Bone Marrow Transplantation in Patients with Acute Nonlymphocytic Leukemia, Using ex Vivo Marrow Treatment with 4-Hydroperoxycyclophosphamide

1986 • 454 citations

Daunomycin-induced cardiotoxicity in children and adults

1977 • 428 citations

High-dose cytosine arabinoside therapy for refractory leukemia

1983 • 372 citations

Intensified induction and consolidation with or without maintenance chemotherapy for acute myeloid leukemia (AML): two multicenter studies of the German AML Cooperative Group.

1985 • 366 citations

PRINCIPAL RESULTS OF THE MEDICAL RESEARCH COUNCIL'S 8th ACUTE MYELOID LEUKAEMIA TRIAL

1986 • 329 citations

Agar Culture Studies in 127 Cases of Untreated Acute Leukemia: The Prognostic Value of Reclassification of Leukemia According to In Vitro Growth Characteristics

1974 • 303 citations

Intravenous Immune Globulin for Prevention of Cytomegalovirus Infection and Interstitial Pneumonia After Bone Marrow Transplantation

1987 • 302 citations

Morphological classification, response to therapy, and survival in 263 adult patients with acute nonlymphoblastic leukemia

1980 • 292 citations

High dose cytosine arabinoside (HDARAC) in refractory acute leukemia

1979 • 290 citations

Mitoxantrone: A New Anticancer Drug with Significant Clinical Activity

1986 • 288 citations

Transplantation of Marrow from an Unrelated Donor to a Patient with Acute Leukemia

1980 • 284 citations

Chemotherapy for acute myelogenous leukemia in children and adults: VAPA update

1983 • 279 citations

HOW DOES BONE-MARROW TRANSPLANTATION CURE LEUKAEMIA?

1984 • 277 citations

Total body irradiation and high-dose etoposide: a new preparatory regimen for bone marrow transplantation in patients with advanced hematologic malignancies [published erratum appears in Blood 1987 Jun;69(6):1789]

1987 • 248 citations

Surface marker analysis of acute myeloblastic leukemia: identification of differentiation-associated phenotypes

1983 • 236 citations

Retinoic acid treatment of acute promyelocytic leukemia: in vitro and in vivo observations

1983 • 235 citations

A critical appraisal of low-dose cytosine arabinoside in patients with acute non-lymphocytic leukemia and myelodysplastic syndromes.

1986 • 225 citations

Acute promyelocytic leukemia

1986 • 224 citations

High-Resolution Chromosomes as an Independent Prognostic Indicator in Adult Acute Nonlymphocytic Leukemia

1984 • 224 citations

THE PLACE OF BONE-MARROW TRANSPLANTATION IN ACUTE MYELOGENOUS LEUKÆMIA

1980 • 220 citations

Acute Leukemia Following Prolonged Cytotoxic Agent Therapy

1979 • 207 citations

High-dose cytosine arabinoside and mitoxantrone: a highly effective regimen in refractory acute myeloid leukemia

1987 • 201 citations

Causes of initial remission induction failure in acute myelogenous leukemia

1982 • 201 citations

Bone Marrow Transplantation or Chemotherapy After Remission Induction for Adults with Acute Nonlymphoblastic Leukemia

1984 • 196 citations

Treatment of poor risk acute leukemia with sequential high-dose ARA-C and asparaginase

1984 • 195 citations

Progress and Perspectives in the Chemotherapy of Acute Leukemia

1965 • 183 citations

High-dose cytosine arabinoside therapy with and without anthracycline antibiotics for remission reinduction of acute nonlymphoblastic leukemia.

1985 • 181 citations

Does treatment with ARA-C in low dosage cause differentiation of leukemic cells?

1983 • 175 citations

CHEMOIMMUNOTHERAPY OF ADULT ACUTE LEUKÆMIA PROLONGATION OF REMISSION IN MYELOBLASTIC LEUKÆMIA WITH B.C.G.

1974 • 172 citations

Marrow Transplantation for Malignant Disease

1987 • 171 citations

Improved Treatment Results in Childhood Acute Myelogenous Leukemia: An Update of the German Cooperative Study AML-BFM-78

1985 • 167 citations

Treatment of Acute Myelogenous Leukemia

1985 • 163 citations

Histocompatible unrelated volunteer donors compared with HLA nonidentical family donors in marrow transplantation for aplastic anemia and leukemia

1986 • 158 citations

A randomized study of the efficacy of consolidation therapy in adult acute nonlymphocytic leukemia

1984 • 154 citations

Treatment of acute nonlymphocytic leukemia: use of anthracycline- cytosine arabinoside induction therapy and comparison of two maintenance regimens

1979 • 153 citations

Allogeneic marrow transplantation for acute nonlymphoblastic leukemia after first relapse

1983 • 153 citations

Bone marrow transplantation in patients aged 45 years and older

1986 • 150 citations

Full dose versus attenuated dose daunorubicin, cytosine arabinoside, and 6-thioguanine in the treatment of acute nonlymphocytic leukemia in the elderly.

1984 • 149 citations

Phase I-II clinical and pharmacologic studies of high-dose cytosine arabinoside in refractory leukemia

1986 • 139 citations

Intensive Chemotherapy for Acute Myelogenous Leukemia

1981 • 135 citations

Therapy of Secondary Acute Nonlymphocytic Leukemia with Cytarabine

1983 • 133 citations

Natural history of central nervous system acute leukemia in adults

1981 • 132 citations

GRAFT REJECTION AND GRAFT-VERSUS-HOST DISEASE: MIRROR IMAGES

1986 • 128 citations

A four-year experience with anthracycline, cytosine arabinoside, vincristine and prednisone combination chemotherapy in 325 adults with acute leukemia

1981 • 124 citations

Two-cycle timed-sequential chemotherapy for adult acute nonlymphocytic leukemia

1984 • 124 citations

High-dose cytosine arabinoside and m-AMSA is effective therapy in relapsed acute nonlymphocytic leukemia.

1984 • 119 citations

ACUTE MYELOGENOUS LEUKAEMIA: MAINTENANCE CHEMOTHERAPY AFTER EARLY CONSOLIDATION TREATMENT DOES NOT PROLONG SURVIVAL

1984 • 119 citations

Marrow transplantation for patients with acute nonlymphoblastic leukemia who achieve a first remission.

1982 • 114 citations

Epsilon-Aminocaproic Acid in the Treatment of Patients with Acute Promyelocytic Leukemia and Acquired Alpha-2-Plasmin Inhibitor Deficiency

1986 • 113 citations

Bone marrow transplantation in acute leukemia.

1982 • 112 citations

Prognostic factors in acute leukemia.

1976 • 112 citations

A randomized comparison of postremission therapy in acute myelogenous leukemia: a Southeastern Cancer Study Group trial

1984 • 108 citations

Intensive chemotherapy is the treatment of choice for elderly patients with acute myelogenous leukemia

1981 • 108 citations

RECONSTITUTION OF HAEMOPOIETIC SYSTEM WITH AUTOLOGOUS MARROW TAKEN DURING RELAPSE OF ACUTE MYELOBLASTIC LEUKAEMIA AND GROWN IN LONG-TERM CULTURE

1986 • 107 citations

Evaluation of AMSA in previously treated patients with acute leukemia: results of therapy in 109 adults

1982 • 105 citations

Allogeneic Marrow Transplantation in the Treatment of Preleukemia

1984 • 104 citations

Treatment of acute leukemia during pregnancy: presentation of nine cases.

1980 • 99 citations

The chromosomes in human leukemia.

1986 • 94 citations

13-cis retinoic acid treatment for myelodysplastic syndromes.

1986 • 94 citations

Acute monoblastic leukemia in infancy and early childhood: successful treatment with an epipodophyllotoxin

1984 • 90 citations

Remission maintenance therapy in acute myelogenous leukemia.

1977 • 89 citations

Controversies in the therapy of acute myelogenous leukemia

1982 • 86 citations

Bone marrow transplantation for acute leukemia: recent advances and comparison with alternative therapies.

1987 • 84 citations

Minimal Residual Disease in Acute Leukemia

1984 • 81 citations

Marrow transplantation for children in first remission of acute nonlymphoblastic leukemia: an update

1985 • 79 citations

The use of intermediate dose cytosine arabinoside (ID Ara‐C) in the treatment of acute non‐lymphocytic leukaemia in relapse

1984 • 79 citations

Monoclonal antibodies to myeloid differentiation antigens: in vivo studies of three patients with acute myelogenous leukemia

1983 • 78 citations

Bone marrow ablation followed by allogeneic marrow grafting during first complete remission of acute nonlymphocytic leukemia

1983 • 78 citations

High-dose combination chemotherapy for acute nonlymphoblastic leukemia in adults

1981 • 75 citations

Homoharringtonine: an effective new drug for remission induction in refractory nonlymphoblastic leukemia.

1985 • 75 citations

Autologous bone marrow transplantation in acute myelogenous leukemia: in vitro treatment with myeloid cell-specific monoclonal antibodies.

1986 • 74 citations

Donor cell leukemia developing six years after marrow grafting for acute leukemia

1985 • 73 citations

Coagulation Defects in Acute Promyelocytic Leukemia

1969 • 73 citations

Late Intensification Therapy for Acute Leukemia in Remission

1976 • 70 citations

Subpopulation heterogeneity in human acute myeloid leukemia determined by monoclonal antibodies

1984 • 69 citations

Acute promyelocytic leukemia. Management of the coagulopathy during daunorubicin-prednisone remission induction

1978 • 68 citations

Amsacrine (AMSA)--a clinical review.

1985 • 67 citations

Distribution of 250 Cases of Acute Myeloid Leukaemia (AML) according to the FAB Classification and Response to Therapy

1981 • 62 citations

Treatment of acute myelogenous leukemia: Influence of three induction regimens and maintenance with chemotherapy or BCG immunotherapy

1982 • 60 citations

Autologous bone marrow transplantation following high dose chemotherapy for the treatment of adult patients with acute myeloid leukaemia

1986 • 57 citations

The treatment of acute myelocytic leukemia in patients 30 years of age and younger

1982 • 51 citations

Adult acute leukemia.Frequency of central nervous system involvement in long term survivors

1977 • 51 citations

Acute leukemia as a terminal event in nonleukemic hematopoietic disorders.

1976 • 47 citations

Primary therapy of acute promyelocytic leukemia: results of amsacrine- and daunorubicin-based therapy

1984 • 47 citations

Consequences of acute myelogenous leukemia in early pregnancy

1977 • 45 citations

The role of immunotherapy in acute myelogenous leukemia.

1983 • 44 citations

13 Bone Marrow Transplantation in Acute Leukaemia

1986 • 41 citations

Prediction of response of patients with acute nonlymphocytic leukaemia to remission induction therapy: use of clinical measurements

1986 • 40 citations

EVALUATION OF THE USE OF HIGH-DOSE CYTOREDUCTION WITH AUTOLOGOUS MARROW RESCUE IN VARIOUS MALIGNANCIES

1986 • 39 citations

Recognition of drug resistance during remission induction therapy for acute non-lymphocytic leukemia: Utility of day 6 bone marrow biopsy

1983 • 39 citations

Acute megakaryoblastic leukemia

1982 • 38 citations

Intensification therapy for acute nonlymphoblastic leukemia in adults

1983 • 36 citations

Progress in Acute Myelogenous Leukemia

1984 • 34 citations

Mismatched family bone marrow transplantation.

1984 • 33 citations

Graft failure and leukemia relapse following T lymphocyte-depleted bone marrow transplants: effect of intensification of immunosuppressive conditioning.

1987 • 31 citations

Charles F. Kettering prize. Acute leukemia. A prototype of disseminated cancer

1984 • 29 citations

ACUTE MEGAKARYOCYTIC LEUKEMIA

1948 • 28 citations

Diaziquone given as a continuous infusion is an active agent for relapsed adult acute nonlymphocytic leukemia

1986 • 27 citations

POTENTIAL UTILIZATION OF A NATIONAL HLA-TYPED DONOR POOL FOR BONE MARROW TRANSPLANTATION

1986 • 26 citations

Bone marrow transplantation for acute leukemia and lymphoma with high-dose cytosine arabinoside and total body irradiation.

1987 • 24 citations

Bone marrow transplantation performed as first-time treatment in two cases of secondary acute myeloid leukemia

1984 • 21 citations

A randomized clinical trial of remission induction, consolidation, and chemo-immunotherapy maintenance in adult acute myeloblastic leukemia

1978 • 20 citations

High-dose cytosine arabinoside and daunomycin as primary therapy for adults with acute nonlymphoblastic leukemia: a pilot study.

1985 • 19 citations

Therapeutic leukopheresis of acute myelo‐monocytic leukemia in pregnancy

1978 • 16 citations

Acute Nonlymphocytic Leukemia in the Elderly: Biology and Treatment

1982 • 15 citations

Response to 5-azacytidine in patients with refractory acute nonlymphocytic leukemia and association with chromosome findings

1982 • 14 citations

Treatment of acute leukaemia with m-AMSA in combination with cytosine arabinoside

1986 • 14 citations

Clinical trials of adult acute nonlymphocytic leukemia: evidence of progress

1985 • 12 citations

Evaluation of cyclocytidine in reinduction and maintenance therapy of children with acute nonlymphocytic leukemia previously treated with cytosine arabinoside: A report from children's cancer study group

1984 • 12 citations

Treatment of acute myeloid leukemia with a combination of intensive induction chemotherapy, early consolidation, splenectomy and long‐term maintenance chemotherapy

1984 • 10 citations