Cloning and disruption of the yeast C‐8 sterol isomerase gene

Experiments in molecular genetics

1972 • 28,260 citations

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Methods in yeast genetics

1979 • 7,824 citations

Methods in Yeast Genetics

1988 • 4,905 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

Sterol, Structure and Membrane Function

1983 • 652 citations

PHOSPHOLIPID BIOSYNTHESIS IN YEAST

1989 • 326 citations

One-Step Gene Disruption in Yeast

1989 • 310 citations

Multiple functions for sterols in Saccharomyces cerevisiae

1985 • 260 citations

The yeast gene ERG6 is required for normal membrane function but is not essential for biosynthesis of the cell-cycle-sparking sterol.

1989 • 259 citations

Yeast mutants deficient in heme biosynthesis and a heme mutant additionally blocked in cyclization of 2,3-oxidosqualene.

1977 • 231 citations

Polyene Resistance and the Isolation of Sterol Mutants in Saccharomyces cerevisiae

1972 • 130 citations

A protein kinase antigenically related to pp60v-src possibly involved in yeast cell cycle control: positive in vivo regulation by sterol.

1987 • 124 citations

Structural and physiological features of sterols necessary to satisfy bulk membrane and sparking requirements in yeast sterol auxotrophs

1983 • 110 citations

Stereochemical specificity for sterols in Saccharomyces cerevisiae.

1983 • 83 citations

Isolation of mutant Saccharomyces cerevisiae strains that survive without sphingolipids.

1990 • 82 citations

Biosynthesis of terpenes and steroids. Part IX. The sterols of some mutant yeasts and their relationship to the biosynthesis of ergosterol

1974 • 76 citations

The Yeast Gene ERG6 Is Required for Normal Membrane Function but Is Not Essential for Biosynthesis of the Cell-Cycle-Sparking Sterol

1989 • 75 citations

Yeast mutants blocked in removing the methyl group of lanosterol at C-14. Separation of sterols by high-pressure liquid chromatography

1977 • 71 citations

Stereochemically distinct roles for sterol in Saccharomycescerevisiae

1983 • 56 citations

Microsomal enzymes of cholesterol biosynthesis from lanosterol. Solubilization and purification of steroid 8-isomerase.

1986 • 56 citations

Isolation of Mutant Saccharomyces cerevisiae Strains That Survive without Sphingolipids

1990 • 19 citations