Distribution of intraneuronal immunoreactivity for the prion protein in human prion diseases

Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects

1999 • 1,354 citations

NMR solution structure of the human prion protein

2000 • 1,075 citations

Prion Diseases and the BSE Crisis

1997 • 952 citations

A Transmembrane Form of the Prion Protein in Neurodegenerative Disease

1998 • 724 citations

Truncated Forms of the Human Prion Protein in Normal Brain and in Prion Diseases

1995 • 497 citations

Scrapie prion proteins are synthesized in neurons.

1986 • 422 citations

Transmissible and genetic prion diseases share a common pathway of neurodegeneration

1999 • 302 citations

Changes in the localization of brain prion proteins during scrapie infection

1987 • 268 citations

Prion infection impairs the cellular response to oxidative stress

2000 • 213 citations

Prion and prejudice: normal protein and the synapse

2001 • 193 citations

Prion Protein-Deficient Neurons Reveal Lower Glutathione Reductase Activity and Increased Susceptibility to Hydrogen Peroxide Toxicity

1999 • 191 citations

The Original Gerstmann‐Sträussler‐Scheinker Family of Austria: Divergent Clinicopathological Phenotypes but Constant PrP Genotype

1995 • 137 citations

Prion protein immunocytochemistry – UK five centre consensus report

1997 • 122 citations

Immunohistochemistry for the Prion Protein: Comparison of Different Monoclonal Antibodies in Human Prion Disease Subtypes

2002 • 116 citations

In Vivo Conversion of Cellular Prion Protein to Pathogenic Isoforms, as Monitored by Conformation-specific Antibodies

2001 • 106 citations

PrPSc-like prion protein peptide inhibits the function of cellular prion protein

2000 • 97 citations

Immunohistochemical localization of prion protein in spongiform encephalopathies and normal brain tissue

1990 • 85 citations

Marked increase of neuronal prion protein immunoreactivity in Alzheimer's disease and human prion diseases

2001 • 81 citations

Oxidative Damage to Nucleic Acids in Human Prion Disease

2002 • 77 citations

Ultrastructural and immunohistochemical studies on ballooned cortical neurons in Creutzfeldt-Jakob disease: expression of ?B-crystallin, ubiquitin and stress-response protein 27

1992 • 76 citations

Differential expression of cellular prion protein in mouse brain as detected with multiple anti-PrP monoclonal antibodies

2001 • 63 citations

Prion protein immunoreactivity in brain samples from an unselected autopsy population: findings in 200 consecutive cases

2000 • 53 citations

Clinicopathological phenotype of codon 129 valine homozygote sporadic Creutzfeldt–Jakob disease

2000 • 48 citations

Histopathology and immunohistochemistry of human transmissible spongiform encephalopathies (TSEs)

2000 • 31 citations

Prominent Stress Response of Purkinje Cells in Creutzfeldt–Jakob Disease

2001 • 31 citations