Prion protein immunoreactivity in brain samples from an unselected autopsy population: findings in 200 consecutive cases

A new variant of Creutzfeldt-Jakob disease in the UK

1996 • 2,690 citations

Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD

1996 • 1,740 citations

Precursor of amyloid protein in Alzheimer disease undergoes fast anterograde axonal transport.

1990 • 735 citations

Prion (PrPSc)-specific epitope defined by a monoclonal antibody

1997 • 565 citations

Early detection of axonal injury after human head trauma using immunocytochemistry for ?-amyloid precursor protein

1994 • 348 citations

Changes in the localization of brain prion proteins during scrapie infection

1987 • 268 citations

Mutant prion proteins in Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles

1992 • 240 citations

Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene

1992 • 204 citations

Fatal familial insomnia

1992 • 200 citations

Natural and experimental oral infection of nonhuman primates by bovine spongiform encephalopathy agents

1999 • 182 citations

Synaptic pathology and glial responses to neuronal injury precede the formation of senile plaques and amyloid deposits in the aging cerebral cortex.

1994 • 166 citations

Coexistence of Alzheimer-type neuropathology in Creutzfeldt-Jakob disease

1998 • 144 citations

Rapid anterograde axonal transport of the cellular prion glycoprotein in the peripheral and central nervous systems.

1994 • 126 citations

Prion protein immunocytochemistry – UK five centre consensus report

1997 • 122 citations

Neuropathology of spongiform encephalopathies in humans

1993 • 115 citations

Regulation and Expression of the Alzheimer's β/A4 Amyloid Protein Precursor in Health, Disease, and Down's Syndromea

1993 • 115 citations

Deposition of ?/A4 protein along neuronal plasma membranes in diffuse senile plaques

1991 • 105 citations

Immunohistochemical localization of prion protein in spongiform encephalopathies and normal brain tissue

1990 • 85 citations

Cerebral white matter damage in HIV infection demonstrated using β-amyloid precursor protein immunoreactivity

1997 • 80 citations

Atypical Creutzfeldt‐Jakob disease in an American family with an insert mutation in the PRNP amyloid precursor gene

1992 • 58 citations

Ubiquitin immunocytochemistry in human spongiform encephalopathies

1993 • 54 citations

Prion protein immunocytochemistry: reliable protocols for the investigation of Creutzfeldt–Jakob disease

1994 • 54 citations

Murine scrapie-infected neurons in vivo release excess prion protein into the extracellular space

1994 • 50 citations

Bundles of amyloid precursor protein-immunoreactive axons in human cerebrovascular white matter lesions

1994 • 47 citations

Immunoreactivity of cerebral amyloidosis is enhanced by protein denaturation treatments

1991 • 28 citations

An antibody raised against a conserved sequence of the prion protein recognizes pathological isoforms in human and animal prion diseases, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy.

1998 • 21 citations