Intercellular junctions and cell adhesion in epithelial cells

Integrins: A family of cell surface receptors

1987 • 4,322 citations

JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA

1963 • 3,559 citations

Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator

1991 • 3,314 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

INTRACELLULAR CALCIUM HOMEOSTASIS

1987 • 2,183 citations

Integrins and other cell adhesion molecules

1990 • 1,990 citations

Calcium regulation of growth and differentiation of mouse epidermal cells in culture

1980 • 1,810 citations

Identification of a Chromosome 18q Gene that Is Altered in Colorectal Cancers

1990 • 1,747 citations

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

1991 • 1,685 citations

The cadherins: cell-cell adhesion molecules controlling animal morphogenesis

1988 • 1,626 citations

E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells.

1991 • 1,592 citations

Identification of ZO-1: a high molecular weight polypeptide associated with the tight junction (zonula occludens) in a variety of epithelia.

1986 • 1,588 citations

HEXAGONAL ARRAY OF SUBUNITS IN INTERCELLULAR JUNCTIONS OF THE MOUSE HEART AND LIVER

1967 • 1,482 citations

The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species.

1989 • 1,393 citations

Structure and Function of Intercellular Junctions

1974 • 1,339 citations

CADHERINS: A MOLECULAR FAMILY IMPORTANT IN SELECTIVE CELL-CELL ADHESION

1990 • 1,293 citations

Connexin43: a protein from rat heart homologous to a gap junction protein from liver.

1987 • 1,111 citations

Signal transduction through the fibronectin receptor induces collagenase and stromelysin gene expression.

1989 • 1,073 citations

Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule

1989 • 973 citations

Junctional intercellular communication and the control of growth

1979 • 965 citations

Identification and spatial distribution of retinoids in the developing chick limb bud

1987 • 964 citations

Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin-mediated cell-cell adhesion.

1989 • 961 citations

Polarized monolayers formed by epithelial cells on a permeable and translucent support

1978 • 869 citations

Cell binding function of E-cadherin is regulated by the cytoplasmic domain.

1988 • 811 citations

A 130K protein from chicken gizzard: Its localization at the termini of microfilament bundles in cultured chicken cells

1979 • 794 citations

Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule.

1990 • 753 citations

Transformation of cell adhesion properties by exogenously introduced E-cadherin cDNA

1987 • 752 citations

Molecular cloning of cDNA for rat liver gap junction protein.

1986 • 715 citations

Differential phosphorylation of the gap junction protein connexin43 in junctional communication-competent and -deficient cell lines.

1990 • 697 citations

Structure of the junction between communicating cells

1980 • 697 citations

Paxillin: a new vinculin-binding protein present in focal adhesions.

1990 • 687 citations

A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family

1989 • 680 citations

Local application of retinoic acid to the limb bond mimics the action of the polarizing region

1982 • 669 citations

Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

1988 • 653 citations

Epidermal differentiation: the bare essentials.

1990 • 651 citations

The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells.

1990 • 629 citations

Barrier function of epithelia

1981 • 616 citations

α-Actinin: Immunofluorescent localization of a muscle structural protein in nonmuscle cells

1975 • 599 citations

Vinculin: A cytoskeletal target of the transforming protein of rous sarcoma virus

1981 • 591 citations

The hematopoietic and epithelial forms of CD44 are distinct polypeptides with different adhesion potentials for hyaluronate-bearing cells.

1991 • 587 citations

Integrin alpha 6/beta 4 complex is located in hemidesmosomes, suggesting a major role in epidermal cell-basement membrane adhesion.

1991 • 574 citations

Morphological factors influencing transepithelial permeability: A model for the resistance of theZonula Occludens

1978 • 569 citations

A human lymphocyte homing receptor, the Hermes antigen, is related to cartilage proteoglycan core and link proteins

1989 • 568 citations

Elimination of Metabolic Cooperation in Chinese Hamster Cells by a Tumor Promoter

1979 • 559 citations

THE ULTRASTRUCTURE OF THE CAT MYOCARDIUM

1969 • 553 citations

Connexin family of gap junction proteins

1990 • 553 citations

Structure, biochemistry, and assembly of epithelial tight junctions

1987 • 532 citations

Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1.

1991 • 520 citations

Membrane ultrastructure at mammalian intercellular junctions

1973 • 516 citations

Structural basis for physiological regulation of paracellular pathways in intestinal epithelia

1987 • 514 citations

A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide.

1986 • 510 citations

Plakoglobin: A protein common to different kinds of intercellular adhering junctions

1986 • 508 citations

Cingulin, a new peripheral component of tight junctions

1988 • 505 citations

Gap junction structures: Analysis of the x-ray diffraction data

1977 • 501 citations

The 102 kd cadherin-associated protein: Similarity to vinculin and posttranscriptional regulation of expression

1991 • 501 citations

Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)

1991 • 481 citations

Localization of specificity determining sites in cadherin cell adhesion molecules

1990 • 475 citations

Propagation of Action Potentials and the Structure of the Nexus in Cardiac Muscle

1965 • 465 citations

Morphoregulatory molecules

1988 • 460 citations

Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton.

1989 • 457 citations

Physiology and Pharmacology of Gap Junctions

1985 • 452 citations

FINE STRUCTURE OF DESMOSOMES, HEMIDESMOSOMES, AND AN ADEPIDERMAL GLOBULAR LAYER IN DEVELOPING NEWT EPIDERMIS

1966 • 450 citations

The function of tight junctions in maintaining differences in lipid composition between the apical and the basolateral cell surface domains of MDCK cells.

1986 • 446 citations

Cloning and characterization of human and rat liver cDNAs coding for a gap junction protein.

1986 • 443 citations

An interaction between vinculin and talin

1984 • 442 citations

Transmembrane control of cadherin-mediated cell adhesion: a 94 kDa protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin.

1989 • 436 citations

Antibodies to gap-junctional protein selectively disrupt junctional communication in the early amphibian embryo

1984 • 434 citations

Effects of cytochalasin D on occluding junctions of intestinal absorptive cells: further evidence that the cytoskeleton may influence paracellular permeability and junctional charge selectivity.

1986 • 433 citations

Cell-adhesion molecule uvomorulin is localized in the intermediate junctions of adult intestinal epithelial cells.

1985 • 429 citations

Sequence and tissue distribution of a second protein of hepatic gap junctions, Cx26, as deduced from its cDNA.

1989 • 427 citations

Methods in Membrane Biology

1978 • 417 citations

Growth inhibition of transformed cells correlates with their junctional communication with normal cells

1986 • 416 citations

Occluding junction structure-function relationships in a cultured epithelial monolayer.

1985 • 412 citations

Cell to substratum contacts of chick fibroblasts and their relation to the microfilament system. a correlated interference-reflexion and high-voltage electron-microscope study

1978 • 409 citations

Identification and purification of a cell surface glycoprotein mediating intercellular adhesion in embryonic and adult tissue

1983 • 396 citations

Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels

1991 • 394 citations

Neural cell adhesion molecules influence second messenger systems

1989 • 387 citations

Immunoelectron microscope studies of membrane-microfilament interactions: distributions of alpha-actinin, tropomyosin, and vinculin in intestinal epithelial brush border and chicken gizzard smooth muscle cells.

1981 • 386 citations

Identification of a cadherin cell adhesion recognition sequence

1990 • 382 citations

Characterization of the class III collagen receptor, a phosphorylated, transmembrane glycoprotein expressed in nucleated human cells.

1988 • 382 citations

Human keratinocytes express a new CD44 core protein (CD44E) as a heparan-sulfate intrinsic membrane proteoglycan with additional exons.

1991 • 377 citations

Experimental modulation of occluding junctions in a cultured transporting epithelium.

1980 • 375 citations

cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide.

1986 • 374 citations

Two configurations of a channel-forming membrane protein

1984 • 368 citations

The uvomorulin-anchorage protein alpha catenin is a vinculin homologue.

1991 • 364 citations

Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases.

1986 • 355 citations

Intestinal absorptive cell tight junctions are linked to cytoskeleton

1987 • 343 citations

Gap junction structures. I. Correlated electron microscopy and x-ray diffraction.

1977 • 341 citations

Novel function for beta 1 integrins in keratinocyte cell-cell interactions.

1990 • 338 citations

Cell-cell interactions in early embryogenesis: A molecular approach to the role of calcium

1981 • 338 citations

Adhesion plaques of Rous sarcoma virus-transformed cells contain the src gene product.

1980 • 334 citations

Monoclonal antibodies to human lymphocyte homing receptors define a novel class of adhesion molecules on diverse cell types.

1989 • 327 citations

Occluding junctions and cytoskeletal components in a cultured transporting epithelium

1980 • 327 citations

Topology of the 32-kd liver gap junction protein determined by site-directed antibody localizations.

1988 • 327 citations

Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules.

1990 • 327 citations

Carbon dioxide reversibly abolishes ionic communication between cells of early amphibian embryo

1977 • 323 citations

Molecular nature of the calcium-dependent cell-cell adhesion system in mouse teratocarcinoma and embryonic cells studied with a monoclonal antibody

1984 • 318 citations

Dependence of junctional conductance on proton, calcium and magnesium ions in cardiac paired cells of guinea‐pig.

1987 • 316 citations

Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated.

1991 • 310 citations

Association of type 3 protein kinase C with focal contacts in rat embryo fibroblasts.

1989 • 310 citations

Activation of pp60c-src protein kinase activity in human colon carcinoma.

1987 • 306 citations

Steps in the morphogenesis of a polarized epithelium : I. uncoupling the roles of cell-cell and cell-substratum contact in establishing plasma membrane polarity in multicellular epithelial (MDCK) cysts

1990 • 302 citations

Construction of epithelioid sheets by transfection of mouse sarcoma cells with cDNAs for chicken cell adhesion molecules.

1988 • 301 citations

Stratification and terminal differentiation of cultured epidermal cells

1982 • 300 citations

Calcium-induced reorganization of desmosomal components in cultured human keratinocytes.

1984 • 300 citations

Influence of collagen gel on the orientation of epithelial cell polarity: follicle formation from isolated thyroid cells and from preformed monolayers.

1981 • 296 citations

Regulation of epithelial tight junction permeability by cyclic AMP

1981 • 296 citations

Characterization of L-CAM, a major cell adhesion molecule from embryonic liver cells

1983 • 289 citations

Neural Tissues Express High Levels of the Cellular src Gene Product pp60^c-src

1983 • 288 citations

Single amino acid substitutions in one Ca2+ binding site of uvomorulin abolish the adhesive function

1990 • 286 citations

Lumen formation by epithelial cell lines in response to collagen overlay: a morphogenetic model in culture.

1982 • 282 citations

Desmosomes and Hemidesmosomes: Constitutive Molecular Components

1990 • 280 citations

Structure of the human desmoplakins. Implications for function in the desmosomal plaque.

1990 • 275 citations

Permeability of the Cell-to-Cell Membrane Channels in Mammalian Cell Junction

1979 • 274 citations

Cytoplasmic filaments and morphogenetic movement in the amphibian neural tube

1967 • 272 citations

Biochemical properties of glycoproteins involved in lymphocyte recognition of high endothelial venules in man.

1988 • 257 citations

Permeability of a cell junction and the local cytoplasmic free ionized calcium concentration: A study with aequorin

1976 • 254 citations

Twenty-first Bowditch lecture. The epithelial junction: bridge, gate, and fence.

1977 • 250 citations

Presence of an SH2 Domain in the Actin-Binding Protein Tensin

1991 • 248 citations

Identification of a putative cell adhesion domain of uvomorulin.

1985 • 246 citations

The Cranial Arachnoid and Pia Mater in Man: Anatomical and Ultrastructural Observations

1988 • 242 citations

A-CAM: a 135-kD receptor of intercellular adherens junctions. I. Immunoelectron microscopic localization and biochemical studies.

1986 • 241 citations

The Structure and Function of Intercellular Junctions in Cancer

1976 • 240 citations

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: Homophilic and heterophilic adhesion

1989 • 236 citations

A 135-kd membrane protein of intercellular adherens junctions.

1984 • 235 citations

EFFECTS OF CALCIUM DEPLETION ON THE JUNCTIONAL COMPLEX BETWEEN OXYNTIC CELLS OF GASTRIC GLANDS

1964 • 234 citations

Isolation and characterization of gap junctions from rat liver.

1979 • 228 citations

Structure and biochemistry of mouse hepatic gap junctions

1979 • 228 citations

Rous sarcoma virus transforming protein lacking myristic acid phosphorylates known polypeptide substrates without inducing transformation

1986 • 223 citations

Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein.

1989 • 223 citations

Correct proteolytic cleavage is required for the cell adhesive function of uvomorulin.

1990 • 222 citations

Localization of integrin receptors for fibronectin, collagen, and laminin in human skin. Variable expression in basal and squamous cell carcinomas.

1989 • 221 citations

Phosphotyrosine-containing proteins are concentrated in focal adhesions and intercellular junctions in normal cells.

1985 • 218 citations

Tight junction dynamics: Is paracellular transport regulated?

1988 • 213 citations

A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: purification and characterization.

1989 • 211 citations

Rearrangements of desmosomal and cytoskeletal proteins during the transition from epithelial to fibroblastoid organization in cultured rat bladder carcinoma cells.

1989 • 210 citations

Acidic fibroblast growth factor is a modulator of epithelial plasticity in a rat bladder carcinoma cell line.

1990 • 208 citations

Cell junction and cyclic AMP: I. Upregulation of junctional membrane permeability and junctional membrane particles by administration of cyclic nucleotide or phosphodiesterase inhibitor

1981 • 206 citations

Topological analysis of the major protein in isolated intact rat liver gap junctions and gap junction-derived single membrane structures.

1987 • 205 citations

Molecular heterogeneity of adherens junctions.

1985 • 200 citations

Topological distribution of two connexin32 antigenic sites in intact and split rodent hepatocyte gap junctions.

1988 • 199 citations

Kinetics of desmosome assembly in Madin-Darby canine kidney epithelial cells: temporal and spatial regulation of desmoplakin organization and stabilization upon cell-cell contact. II. Morphological analysis.

1988 • 194 citations

Gap junction structures

1984 • 193 citations

Cloning and sequence analysis of desmosomal glycoproteins 2 and 3 (desmocollins): cadherin-like desmosomal adhesion molecules with heterogeneous cytoplasmic domains.

1991 • 188 citations

Partitioning of paracellular conductance along the ileal crypt-villus axis: A hypothesis based on structural analysis with detailed consideration of tight junction structure-function relationships

1984 • 187 citations

Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules.

1991 • 185 citations

Tumor promoter-induced changes in the permeability of epithelial cell tight junctions

1981 • 185 citations

Specific interaction of vinculin with α-actinin

1987 • 185 citations

Sequence of human syndecan indicates a novel gene family of integral membrane proteoglycans.

1990 • 184 citations

Transforming growth factor beta₁ modulates extracellular matrix organization and cell‐cell junctional complex formation during in vitro angiogenesis

1990 • 184 citations

The actions of retinoids on cellular growth correlate with their actions on gap junctional communication.

1989 • 184 citations

Cytoplasmic regulation of tight-junction permeability: effect of plant cytokinins

1980 • 182 citations

Tumor dedifferentiation: An important step in tumor invasion

1985 • 181 citations

Neural tissues express high levels of the cellular src gene product pp60c-src.

1983 • 179 citations

THE SPLITTING OF HEPATOCYTE GAP JUNCTIONS AND ZONULAE OCCLUDENTES WITH HYPERTONIC DISACCHARIDES

1974 • 179 citations

Intermediate filaments and the initiation of desmosome assembly.

1985 • 175 citations

The epithelial tight junction: Structure, function and preliminary biochemical characterization

1988 • 173 citations

Purification and characterization of zyxin, an 82,000-dalton component of adherens junctions.

1991 • 167 citations

Intracellular pH, intracellular free Ca, and junctional cell-cell coupling

1978 • 167 citations

Intercellular adhesion of rat hepatocytes. Identification of a cell surface glycoprotein involved in the initial adhesion process.

1982 • 167 citations

Actin in the Brush-Border of Epithelial Cells of the Chicken Intestine

1971 • 165 citations

Rapid and reversible reduction of junctional permeability in cells infected with a temperature-sensitive mutant of avian sarcoma virus.

1981 • 164 citations

Effects of tumor promoters on LLC-PK1 renal epithelial tight junctions and transepithelial fluxes

1986 • 163 citations

Lack of correlation between tight junction morphology and permeability properties in developing choroid plexus

1976 • 162 citations

Cloning and Expression of a Xenopus Embryonic Gap Junction Protein

1989 • 161 citations

Homologies between gap junction proteins in lens, heart and liver

1988 • 160 citations

A-CAM: a 135-kD receptor of intercellular adherens junctions. II. Antibody-mediated modulation of junction formation.

1986 • 160 citations

Antibodies to epithelial desmosomes show wide tissue and species cross-reactivity

1983 • 160 citations

The fate of desmosomes in trypsinized tissue

1968 • 158 citations

Ca++-calmodulin-dependent phosphorylation of myosin, and its role in brush border contraction in vitro.

1982 • 157 citations

Cell-cell interaction and polarity of epithelial cells: Specific perturbation using a monoclonal antibody

1983 • 153 citations

A protein homologous to the 27,000 dalton liver gap junction protein is present in a wide variety of species and tissues

1984 • 150 citations

Talin is phosphorylated on tyrosine in chicken embryo fibroblasts transformed by Rous sarcoma virus.

1986 • 149 citations

Molecular polymorphism of a cell surface proteoglycan: distinct structures on simple and stratified epithelia.

1988 • 148 citations

Modulation of the expression of an apical plasma membrane protein of Madin-Darby canine kidney epithelial cells: cell-cell interactions control the appearance of a novel intracellular storage compartment.

1987 • 146 citations

Oxidants increase paracellular permeability in a cultured epithelial cell line.

1985 • 146 citations

Organization of pp60src and selected cytoskeletal proteins within adhesion plaques and junctions of Rous sarcoma virus-transformed rat cells.

1981 • 144 citations

DIFFERENTIATION OF THE JUNCTIONAL COMPLEX OF SURFACE CELLS IN THE DEVELOPING FUNDULUS BLASTODERM

1971 • 144 citations

Intercellular Junctions and Synapses

1978 • 142 citations

Identification of actin-, alpha-actinin-, and vinculin-containing plaques at the lateral membrane of epithelial cells.

1986 • 139 citations

Zonulae occludentes in junctional complex-enriched fractions from mouse liver: preliminary morphological and biochemical characterization.

1984 • 139 citations

Identification of a basic protein of Mr 75,000 as an accessory desmosomal plaque protein in stratified and complex epithelia.

1988 • 138 citations

The role of microtubules and microfilaments in neurulation in Xenopus

1971 • 136 citations

Organization of desmosomal plaque proteins in cells growing at low calcium concentrations.

1988 • 133 citations

Identification of a new protein localized at sites of cell-substrate adhesion.

1986 • 132 citations

Regulation of desmosome assembly in epithelial cells: kinetics of synthesis, transport, and stabilization of desmoglein I, a major protein of the membrane core domain.

1989 • 130 citations

Effect of Wnt-1 and Related Proteins on Gap Junctional Communication in Xenopus Embryos

1991 • 129 citations

Structural homology between lymphocyte receptors for high endothelium and class III extracellular matrix receptor.

1989 • 129 citations

Studies on the development and maintenance of epithelial cell surface polarity with monoclonal antibodies.

1984 • 127 citations

Volume Reabsorption, Transepithelial Potential Differences, and Ionic Permeability Properties in Mammalian Superficial Proximal Straight Tubules

1974 • 127 citations

Interaction of iodinated vinculin, metavinculin and α‐actinin with cytoskeletal proteins

1987 • 123 citations

Desmosome biogenesis in the mouse preimplantation embryo

1991 • 122 citations

Gap junctions in several tissues share antigenic determinants with liver gap junctions.

1984 • 121 citations

Phosphorylation of cellular proteins in Rous sarcoma virus-infected cells: analysis by use of anti-phosphotyrosine antibodies.

1988 • 121 citations

Isolation of cell-to-cell adherens junctions from rat liver.

1989 • 120 citations

Desmosomal glycoproteins II and III. Cadherin-like junctional molecules generated by alternative splicing

1991 • 120 citations

Integrins and tumor invasion

1990 • 119 citations

Antidesmosomal monoclonal antibody in the diagnosis of intracranial tumours

1987 • 119 citations

Growth factors modulate junctional cell-to-cell communication

1988 • 119 citations

Kinetics of desmosome assembly in Madin-Darby canine kidney epithelial cells: temporal and spatial regulation of desmoplakin organization and stabilization upon cell-cell contact. I. Biochemical analysis.

1988 • 119 citations

Ca2+ regulation of tight-junction permeability and structure in Necturus gallbladder

1983 • 118 citations

Diacylglycerol inhibits gap junctional communication in cultured epidermal cells: Evidence for a role of protein kinase C

1985 • 111 citations

Nonmitogenic Morphoregulatory Action of pp6O^v-src on Multicellular Epithelial Structures

1987 • 110 citations

Intercellular communication between ciliated cells in culture

1988 • 110 citations

Reactivation of intestinal epithelial cell brush border motility: ATP-dependent contraction via a terminal web contractile ring.

1982 • 109 citations

Phosphorylation of the tight-junction protein ZO-1 in two strains of Madin-Darby canine kidney cells which differ in transepithelial resistance

1989 • 108 citations

Intercellular communication and the control of growth: X. Alteration of junctional permeability by thesrc gene. A study with temperature-sensitive mutant Rous sarcoma virus

1984 • 106 citations

Major loss of the 28-kD protein of gap junction in proliferating hepatocytes.

1987 • 105 citations

ZO-1 and cingulin: tight junction proteins with distinct identities and localizations

1989 • 105 citations

Splitting and internalization of the desmosomes of cultured kidney epithelial cells by reduction in calcium concentration

1986 • 104 citations

Sequence and developmental expression of mRNA coding for a gap junction protein in Xenopus.

1988 • 103 citations

The cell adhesion molecule Cell‐CAM 105 is an ecto‐ATPase and a member of the immunoglobulin superfamily

1990 • 102 citations

A possible new adhesive site in the cell-adhesion molecule uvomorulin

1990 • 102 citations

Differential effects of the cytoplasmic domains of cell adhesion molecules on cell aggregation and sorting-out.

1990 • 99 citations

Desmocalmin: a calmodulin-binding high molecular weight protein isolated from desmosomes.

1985 • 99 citations

Rat liver gap junction protein: properties and partial sequence.

1981 • 98 citations

Structural heterogeneity of human Pgp-1 and its relationship with p85

1988 • 97 citations

Correlation between numbers of desmosomes and the aggressiveness of transitional cell carcinoma in human urinary bladder

1981 • 96 citations

Structural integrity of hepatocyte tight junctions.

1983 • 95 citations

Phosphorylation of liver gap junction protein by protein kinase C

1987 • 91 citations

Alterations in the expression of a hepatocyte cell adhesion molecule by transplantable rat hepatocellular carcinomas.

1985 • 91 citations

Alteration of tight junctional permeability in the rat parotid gland after isoproterenol stimulation

1984 • 89 citations

Calcium-induced desmosome formation in cultured kidney epithelial cells

1986 • 88 citations

Tight junctions and apical/basolateral polarity

1989 • 87 citations

Vinculin phosphorylation by the src kinase. Interaction of vinculin with phospholipid vesicles.

1983 • 85 citations

Tyrosine phosphorylated proteins in different tissues during chick embryo development.

1988 • 85 citations

Phosphotyrosine-modified proteins are concentrated at the membranes of epithelial and endothelial cells during tissue development in chick embryos.

1988 • 84 citations

Ultrastructure of intermediate stages in polarity reversal of thyroid epithelium in follicles in suspension culture.

1980 • 83 citations

Phosphorylation of talin at tyrosine in Rous sarcoma virus-transformed cells.

1987 • 83 citations

Structure and assembly of desmosome junctions: biosynthesis and turnover of the major desmosome components of Madin-Darby canine kidney cells in low calcium medium.

1987 • 81 citations

Involvement of protein kinase C in translocation of desmoplakins from cytosol to plasma membrane during desmosome formation in human squamous cell carcinoma cells grown in low to normal calcium concentration

1989 • 81 citations

Hormonal regulation of hepatocyte tight junctional permeability

1988 • 78 citations

Interleukin 1 beta induces rapid phosphorylation and redistribution of talin: a possible mechanism for modulation of fibroblast focal adhesion.

1991 • 78 citations

Distribution of desmosomal components in the tissues of vertebrates, studied by fluorescent antibody staining

1984 • 77 citations

Nonmitogenic morphoregulatory action of pp60v-src on multicellular epithelial structures.

1987 • 76 citations

Mechanical tension induces lateral movement of intramembrane components of the tight junction: studies on mouse mammary cells in culture.

1983 • 75 citations

The apical surface of canine chief cell monolayers resists H+ back-diffusion

1985 • 75 citations

Immunohistochemical localization of cellCAM 105 in rat tissues: appearance in epithelia, platelets, and granulocytes.

1988 • 75 citations

Regulation of desmosome assembly in MDCK epithelial cells: coordination of membrane core and cytoplasmic plaque domain assembly at the plasma membrane.

1991 • 74 citations

Tight Junctions in Epithelial Cells of Human Fetal Hindgut, Normal Colon, and Colon Adenocarcinoma<xref ref-type="fn" rid="FN2">2</xref>

1980 • 73 citations

EQUILIBRIUM MEASUREMENTS OF EMBRYONIC CHICK CELL ADHESIVENESS, I. SHAPE EQUILIBRIUM IN CENTRIFUGAL FIELDS

1969 • 73 citations

The molecular biology of desmosomes and hemidesmosomes: ′What's in a name?'

1992 • 73 citations

Uptake and fate of luminally administered horseradish peroxidase in resting and isoproterenol-stimulated rat parotid acinar cells.

1978 • 73 citations

Early expression of desmosomal components during kidney tubule morphogenesis in human and murine embryos

1990 • 72 citations

A new high molecular mass protein showing unique localization in desmosomal plaque.

1989 • 72 citations

Biphasic effects of 12-O-tetradecanoylphorbol-13-acetate on the cell morphology of low calcium-grown human epidermal carcinoma cells: involvement of translocation and down regulation of protein kinase C.

1988 • 72 citations

Conformational changes in the chicken receptor for endocytosis of glycoproteins. Modulation of ligand-binding activity by Ca2+ and pH.

1988 • 70 citations

The gap junction.

1988 • 70 citations

Hormonal regulation of cell junction permeability: Upregulation by catecholamine and prostaglandin E1

1982 • 69 citations

Malignant transformation of urinary bladder in humans and in N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-exposed Fischer rats: ultrastructure of the major components of the permeability barrier.

1977 • 68 citations

Desmosomal glycoproteins 2 and 3 (desmocollins) show N-terminal similarity to calcium-dependent cell-cell adhesion molecules

1990 • 65 citations

Immunolocalization of plakoglobin in endothelial junctions: identification as a special type of Zonulae adhaerentes

1987 • 65 citations

Chemical characterization of cell-CAM 105, a cell-adhesion molecule isolated from rat liver membranes

1986 • 64 citations

Size heterogeneity, phosphorylation and transmembrane organisation of desmosomal glycoproteins 2 and 3 (desmocollins) in MDCK cells

1990 • 64 citations

Occluding junctions in a renal cell line (LLC-PK1) with characteristics of proximal tubular cells

1986 • 63 citations

Diacylglycerol downregulates junctional membrane permeability. TMB-8 blocks this effect

1985 • 63 citations

Structure and assembly of desmosome junctions: biosynthesis, processing, and transport of the major protein and glycoprotein components in cultured epithelial cells.

1987 • 62 citations

Cell junction and cyclic AMP: II. Modulations of junctional membrane permeability, dependent on serum and cell density

1981 • 60 citations

Mouse antisera specific for desmosomal adhesion molecules of suprabasal skin cells, meninges, and meningioma.

1986 • 59 citations

Organization of cytokeratin bundles by desmosomes in rat mammary cells.

1986 • 58 citations

A cell surface desmosome-associated component: identification of tissue-specific cell adhesion molecule.

1986 • 57 citations

Plakoglobin is a component of the filamentous subplasmalemmal coat of lens cells.

1987 • 57 citations

Cellular transformation, tyrosine kinase oncogenes, and the cellular adhesion plaque

1988 • 56 citations

Regulation of cell-to-cell communication by phosphorylation.

1985 • 56 citations

Identification of a conserved region common to cadherins and influenza strain A hemagglutinins

1990 • 55 citations

Altered permeability in the proximal tubule response to cyclic AMP

1979 • 52 citations

C‐CAM (cell‐CAM 105) – a member of the growing immunoglobulin superfamily of cell adhesion proteins

1991 • 52 citations

Mechanism of inhibitory action of TMB-8 [8-(NN-diethylamino)octyl-3,4,5-trimethoxybenzoate] on aldosterone secretion in adrenal glomerulosa cells

1985 • 51 citations

Desmosome development in an in vitro model.

1980 • 48 citations

Development of desmosomal adhesion between MDCK cells following calcium switching

1990 • 48 citations

The Structure and Function of Spot Desmosomes

1981 • 47 citations

Cloning of a gap junctional protein from vascular smooth muscle and expression in two-cell mouse embryos.

1990 • 47 citations

The influence of ethanol on human splanchnic and skeletal muscle metabolism during exercise

1977 • 47 citations

A protein antigenically related to nuclear lamin B mediates the association of intermediate filaments with desmosomes.

1990 • 46 citations

Ultrastructure of cell junctions in FANFT-induced urothelial tumors in urinary bladder of Fischer rats.

1977 • 45 citations

Retinoic acid inhibits junctional communication between animal cells

1986 • 43 citations

Transepithelial permeability in the rabbit pancreas

1979 • 42 citations

A new 400-kD protein from isolated adherens junctions: its localization at the undercoat of adherens junctions and at microfilament bundles such as stress fibers and circumferential bundles.

1989 • 41 citations

A factor in serum lowers resistance and opens tight junctions of MDCK cells

1990 • 40 citations

Heat shock induces protein tyrosine phosphorylation in cultured cells.

1989 • 39 citations

Evidence mounts for the role of gap junctions during development

1988 • 39 citations

Detection of an altered form of cell-CAM 105 on rat transplantable and primary hepatocellular carcinomas.

1989 • 38 citations

Mobilization of the hormone‐sensitive calcium pool increases hepatocyte tight junctional permeability in the perfused rat liver

1991 • 37 citations

A Possible Role of the Desmosome in the Process of Keratinization

1964 • 35 citations

Changes of gap junctions in myometrium of guinea pig at parturition and abortion

1982 • 35 citations

A study of desmosomes in colorectal carcinoma

1990 • 34 citations

Methods for the Isolation and Structural Characterization of Hepatocyte Gap Junctions

1975 • 34 citations

Inhibition of gap-junctional intercellular communication between epithelial cells transformed by the activated H-ras-1 oncogene

1989 • 33 citations

The undercoat of adherens junctions: A key specialized structure in organogenesis and carcinogenesis.

1990 • 33 citations

Preparation of a gap junction fraction from uteri of pregnant rats: the 28-kD polypeptides of uterus, liver, and heart gap junctions are homologous.

1985 • 33 citations

Immunohistochemical Staining with Monoclonal Antibody 32–2B to Desmosomal Glycoprotein 1: Its Role in the Histological Assessment of Urothelial Carcinomas

1990 • 33 citations

Characterization of a 125K glycoprotein associated with bovine epithelial desmosomes

1988 • 31 citations

C-cam (cell-CAM 105) is an adhesive cell surface glycoprotein with homophilic binding properties

1990 • 31 citations

Modification of gap junctions in cells transformed by a temperature-sensitive mutant of Rous sarcoma virus

1986 • 31 citations

Desmosomes and their components after cell dissociation and reaggregation in the presence of cytochalasin B

1973 • 30 citations

Desmoplakin expression and distribution in cultured rat bladder epithelial cells of varying tumorigenic potential

1991 • 28 citations

Adhesion Molecules on the Plasma Membrane of Epidermal Cells. III. Keratinocytes and Langerhans Cells Constitutively Express the Lymphocyte Function-Associated Antigen 3

1991 • 27 citations

The assembly of the major desmosome glycoproteins of Madin‐Darby canine kidney cells

1989 • 25 citations

Gap Junction Structure and the Control of Cell‐to‐Cell Communication

2007 • 24 citations

Distribution of desmoplakin in normal cultured human keratinocytes and in basal cell carcinoma cells

1989 • 23 citations

Downregulation of cell-to-cell communication by the viralsrc gene is blocked by TMB-8 and recovery of communication is blocked by vanadate

1986 • 23 citations

Recognition, Calcium and the Control of Desmosome Formation

2007 • 22 citations

Junctional complexes of epithelial cells.

1987 • 19 citations

The action of v-src on gap junctional permeability is modulated by pH.

1990 • 19 citations

Gap junctions: Towards a molecular structure

1988 • 16 citations

The Adhesions of Epithelial Cells

1985 • 14 citations

Observations on the increase in permeability induced by adrenaline in the submaxillary gland

1964 • 12 citations

Close relationship between modulation of serum-induced stimulation of DNA synthesis and changes in gap-junctional intercellular communication in quiescent 3T3-L1 cells caused by cyclic AMP and the tumor-promoting phorbol ester TPA

1989 • 9 citations

An upward shift of intracellular pH rather than the final absolute pH value is critical for controlling gap junction permeability in tumor promoter‐treated cells

1991 • 6 citations