Neurodegenerative Tauopathies

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

1996 • 4,118 citations

Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

1998 • 3,377 citations

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1995 • 2,456 citations

Mutation in the tau gene in familial multiple system tauopathy with presenile dementia

1998 • 1,440 citations

Tau is a candidate gene for chromosome 17 frontotemporal dementia

1998 • 1,344 citations

Mutation-Specific Functional Impairments in Distinct Tau Isoforms of Hereditary FTDP-17

1998 • 954 citations

MUTANT GENES IN FAMILIAL ALZHEIMER'S DISEASE AND TRANSGENIC MODELS

1998 • 576 citations

Age-Dependent Emergence and Progression of a Tauopathy in Transgenic Mice Overexpressing the Shortest Human Tau Isoform

1999 • 552 citations

Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements

1999 • 506 citations

Aβ Deposition Is Associated with Neuropil Changes, but not with Overt Neuronal Loss in the Human Amyloid Precursor Protein V717F (PDAPP) Transgenic Mouse

1997 • 502 citations

Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17

1998 • 464 citations

Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform.

1995 • 427 citations

Tau Mutations Cause Frontotemporal Dementias

1998 • 267 citations

Effects of frontotemporal dementia FTDP‐17 mutations on heparin‐induced assembly of tau filaments

1999 • 253 citations

Segregation of a Missense Mutation in the Microtubule-Associated Protein Tau Gene with Familial Frontotemporal Dementia and Parkinsonism

1998 • 236 citations

Transgenic Expression of the Shortest Human Tau Affects Its Compartmentalization and Its Phosphorylation as in the Pretangle Stage of Alzheimer's Disease

1999 • 194 citations

Human tau becomes phosphorylated and forms filamentous deposits when overexpressed in lamprey central neurons in situ

1997 • 76 citations