The colony stimulating factors

Structural design and molecular evolution of a cytokine receptor superfamily.

1990 • 2,104 citations

THE GROWTH OF MOUSE BONE MARROW CELLS IN VITRO

1966 • 1,944 citations

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

Antigenic analysis of hematopoiesis. III. A hematopoietic progenitor cell surface antigen defined by a monoclonal antibody raised against KG-1a cells.

1984 • 1,193 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Effect of Granulocyte Colony-Stimulating Factor on Neutropenia and Associated Morbidity Due to Chemotherapy for Transitional-Cell Carcinoma of the Urothelium

1988 • 961 citations

The cloning of normal “Mast” cells in tissue culture

1965 • 886 citations

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

1990 • 837 citations

Effects of Recombinant Human Granulocyte–Macrophage Colony-Stimulating Factor in Patients with Myelodysplastic Syndromes

1987 • 653 citations

Hematopoietic growth factors.

1987 • 621 citations

Phase I/II study of recombinant human granulocyte colony-stimulating factor in patients receiving intensive chemotherapy for small cell lung cancer

1987 • 605 citations

Molecular physiology of granulocyte-macrophage colony-stimulating factor

1991 • 598 citations

Circulation of CD34+ hematopoietic stem cells in the peripheral blood of high-dose cyclophosphamide-treated patients: enhancement by intravenous recombinant human granulocyte-macrophage colony-stimulating factor

1989 • 549 citations

Steel locus defines new multipotent growth factor

1990 • 509 citations

Molecular physiology of granulocyte-macrophage colony-stimulating factor

1991 • 505 citations

Effects of Recombinant Human Granulocyte Colony-Stimulating Factor on Neutropenia in Patients with Congenital Agranulocytosis

1989 • 495 citations

Precursors of colony-forming cells in humans can be distinguished from colony-forming cells by expression of the CD33 and CD34 antigens and light scatter properties.

1989 • 453 citations

Review: Stratton Lecture 1990. Clinical implications of positive and negative hematopoietic stem cell regulators

1991 • 369 citations

Ex vivo expansion and maturation of peripheral blood CD34+ cells into the myeloid lineage

1992 • 365 citations

Treatment of Cyclic Neutropenia with Granulocyte Colony-Stimulating Factor

1989 • 363 citations

Colony-stimulating factor-1 receptor

1990 • 362 citations

Phase I/II study of recombinant human granulocyte-macrophage colony- stimulating factor in aplastic anemia and myelodysplastic syndrome

1988 • 301 citations

Ex vivo expansion and maturation of peripheral blood CD34+ cells into the myeloid lineage

1992 • 291 citations

Identification and comparison of CD34-positive cells and their subpopulations from normal peripheral blood and bone marrow using multicolor flow cytometry

1991 • 290 citations

The evolving role of autologous peripheral stem cell transplantation following high-dose therapy for malignancies [editorial]

1991 • 290 citations

Purified primitive human hematopoietic progenitor cells with long-term in vitro repopulating capacity adhere selectively to irradiated bone marrow stroma.

1990 • 275 citations

Methods for the purification, assay, characterization and target cell binding of a colony stimulating factor (CSF-1)

1981 • 274 citations

High-dose therapy and autologous peripheral blood stem cell transplantation for patients with lymphoma

1989 • 243 citations

Isolation and characterization of lymphokine cDNA clones encoding mouse and human IgA-enhancing factor and eosinophil colony-stimulating factor activities: relationship to interleukin 5.

1987 • 236 citations

Evidence for the Involvement of GM-CSF and FMS in the Deletion (5q) in Myeloid Disorders

1986 • 233 citations

Long-term erythropoiesis from constant numbers of CD34+ cells in serum-free cultures initiated with highly purified progenitor cells from human bone marrow.

1992 • 231 citations

Successful autologous transplantation of blood stem cells mobilized with recombinant human granulocyte-macrophage colony-stimulating factor.

1990 • 230 citations

Molecular organization of the cytokine gene cluster, involving the human IL-3, IL-4, IL-5, and GM-CSF genes, on human chromosome 5

1989 • 229 citations

Mobilization of peripheral blood progenitor cells by sequential administration of interleukin-3 and granulocyte-macrophage colony- stimulating factor following polychemotherapy with etoposide, ifosfamide, and cisplatin [see comments]

1992 • 216 citations

Characterization of a human hematopoietic progenitor cell capable of forming blast cell containing colonies in vitro.

1988 • 213 citations

Treatment of Myelodysplastic Syndromes with Recombinant Human Granulocyte Colony-Stimulating Factor

1989 • 208 citations

The evolving role of autologous peripheral stem cell transplantation following high-dose therapy for malignancies [editorial]

1991 • 206 citations

Subcutaneous granulocyte-macrophage colony-stimulating factor in patients with myelodysplastic syndrome: toxicity, pharmacokinetics, and hematological effects.

1989 • 179 citations

c-kit protein, a transmembrane kinase: identification in tissues and characterization.

1988 • 167 citations

The colony stimulating factors discovery, development, and clinical applications

1990 • 156 citations

Interleukin-4 and interleukin-5 map to human chromosome 5 in a region encoding growth factors and receptors and are deleted in myeloid leukemias with a del(5q).

1989 • 154 citations

The 5q- abnormality

1987 • 132 citations

Rapid and complete hemopoietic reconstitution following combined transplantation of autologous blood and bone marrow cells. A changing role for high dose chemo‐radiotherapy?

1989 • 117 citations

The Clinical use of Colony Stimulating Factors

1991 • 97 citations

A controlled trial of recombinant human granulocyte-macrophage colony- stimulating factor after total body irradiation, high-dose chemotherapy, and autologous bone marrow transplantation for acute lymphoblastic leukemia or malignant lymphoma

1992 • 91 citations

Further evidence for lymphokine overproduction in severe aplastic anemia [see comments]

1988 • 81 citations

Effects of granulocyte-macrophage colony-stimulating factor on in vitro growth of human solid tumors.

1989 • 46 citations

Anti-cytokine strategies.

1992 • 45 citations

Hematopoietic reconstitution after autologous blood stem cell transplantation: A report of 46 cases

1987 • 42 citations

Human cytokine receptors

1990 • 31 citations

The receptors for regulatory molecules of hematopoiesis

1992 • 28 citations

Review: Hematopoietic Growth Factors: Overview and Clinical Applications, Part I

1990 • 23 citations

Hematopoietic Growth Factors: Overview and Clinical Applications, Part III

1990 • 22 citations

c-kit Protein, a Transmembrane Kinase: Identification in Tissues and Characterization

1988 • 22 citations

Recombinant human hematopoietic growth factors in the treatment of cytopenias

1992 • 11 citations

Aplastic anaemia: pathogenetic mechanisms and treatment with special reference to immunomodulation

1992 • 10 citations