Retroviral Reverse Transcriptases: Error Frequencies and Mutagenesis

The Human Immunodeficiency Virus: Infectivity and Mechanisms of Pathogenesis

1988 • 1,496 citations

Rapid Evolution of RNA Genomes

1982 • 1,475 citations

Frameshift Mutations and the Genetic Code

1966 • 1,400 citations

Multiple Mutations in HIV-1 Reverse Transcriptase Confer High-Level Resistance to Zidovudine (AZT)

1989 • 1,199 citations

The Accuracy of Reverse Transcriptase from HIV-1

1988 • 982 citations

Fidelity of HIV-1 Reverse Transcriptase

1988 • 919 citations

Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase

1988 • 814 citations

Identification and characterization of conserved and variable regions in the envelope gene of HTLV-III/LAV, the retrovirus of AIDS

1986 • 780 citations

Nucleic Acids and Molecular Biology

1994 • 777 citations

Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates

1989 • 662 citations

Retroviral Recombination and Reverse Transcription

1990 • 596 citations

Rapid Evolution of RNA Viruses

1987 • 593 citations

Genetic Variation in HTLV-III/LAV Over Time in Patients with AIDS or at Risk for AIDS

1986 • 570 citations

Fidelity of DNA Synthesis

1982 • 516 citations

Genetic variability of the AIDS virus: Nucleotide sequence analysis of two isolates from African patients

1986 • 513 citations

Extensive variation of human immunodeficiency virus type-1 in vivo

1988 • 415 citations

High fidelity DNA synthesis by theThermus aquaticusDNA polymerase

1990 • 393 citations

The Origin of Genetic Information

1981 • 353 citations

DNA polymerase insertion fidelity. Gel assay for site-specific kinetics.

1987 • 332 citations

Specificity and Mechanism of Error-prone Replication by Human Immunodeficiency Virus-1 Reverse Transcriptase

1989 • 316 citations

The base substitution fidelity of eucaryotic DNA polymerases. Mispairing frequencies, site preferences, insertion preferences, and base substitution by dislocation.

1986 • 301 citations

Biologically diverse molecular variants within a single HIV-1 isolate

1988 • 285 citations

Genetic variation in AIDS viruses

1986 • 279 citations

Human immunodeficiency virus 1 reverse transcriptase

1989 • 244 citations

Identification of conserved and divergent domains within the envelope gene of the acquired immunodeficiency syndrome retrovirus.

1986 • 220 citations

GENERATION OF DIVERSITY IN RETROVIRUSES

1990 • 197 citations

Fidelity of Mammalian DNA Polymerases

1981 • 180 citations

The Infidelity of Avian Myeloblastosis Virus Deoxyribonucleic Acid Polymerase in Polynucleotide Replication

1974 • 172 citations

High mutation rate of a spleen necrosis virus-based retrovirus vector.

1986 • 157 citations

On the Fidelity of DNA Replication

1979 • 144 citations

Reverse transcriptases and genomic variability: the accuracy of DNA replication is enzyme specific and sequence dependent.

1990 • 141 citations

Extension of mismatched 3' termini of DNA is a major determinant of the infidelity of human immunodeficiency virus type 1 reverse transcriptase.

1989 • 132 citations

Rates of evolution of the retroviral oncogene of Moloney murine sarcoma virus and of its cellular homologues.

1985 • 122 citations

Low fidelity of cell-free DNA synthesis by reverse transcriptase of human immunodeficiency virus

1988 • 105 citations

Fidelity of a human cell DNA replication complex.

1988 • 93 citations

Determination of the mutation rate of a retrovirus

1988 • 87 citations

Fidelity of human immunodeficiency virus type I reverse transcriptase in copying natural DNA

1989 • 80 citations

Nucleic Acids and Molecular Biology

1987 • 79 citations

On the fidelity of DNA replication. Isolation of high fidelity DNA polymerase-primase complexes by immunoaffinity chromatography.

1987 • 42 citations

Synthesis of DNA by human immunodeficiency virus reverse transcriptase is preferentially blocked at template oligo(deoxyadenosine) tracts.

1990 • 41 citations

Sequence specificity of pausing by DNA polymerases

1989 • 18 citations