Presynaptic Proteins and Schizophrenia

SNAP receptors implicated in vesicle targeting and fusion

1993 • 3,220 citations

Membrane Fusion

1990 • 2,458 citations

The synaptic vesicle cycle: a cascade of protein–protein interactions

1995 • 2,004 citations

A protein assembly-disassembly pathway in vitro that may correspond to sequential steps of synaptic vesicle docking, activation, and fusion

1993 • 1,893 citations

Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles

1985 • 1,425 citations

Schizophrenia: Caused by a fault in programmed synaptic elimination during adolescence?

1982 • 1,352 citations

Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function

1993 • 1,302 citations

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

1992 • 1,274 citations

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

2001 • 1,194 citations

The reduced neuropil hypothesis: a circuit based model of schizophrenia

1999 • 918 citations

Molecular Characterization of Schizophrenia Viewed by Microarray Analysis of Gene Expression in Prefrontal Cortex

2000 • 884 citations

A 38,000-dalton membrane protein (p38) present in synaptic vesicles.

1985 • 856 citations

The identification of a novel synaptosomal-associated protein, SNAP-25, differentially expressed by neuronal subpopulations.

1989 • 819 citations

Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells.

1986 • 671 citations

VAMP-1: a synaptic vesicle-associated integral membrane protein.

1988 • 574 citations

Complexins: Cytosolic proteins that regulate SNAP receptor function

1995 • 494 citations

Reduction of Synaptophysin Immunoreactivity in the Prefrontal Cortex of Subjects With Schizophrenia

1997 • 334 citations

Microarray analysis of gene expression in the prefrontal cortex in schizophrenia: a preliminary study

2002 • 278 citations

Synaptic and plasticity-associated proteins in anterior frontal cortex in severe mental illness

1999 • 245 citations

Gene Expression Profile for Schizophrenia

2002 • 239 citations

Alterations in synaptic proteins and their encoding mRNAs in prefrontal cortex in schizophrenia: a possible neurochemical basis for ‘hypofrontality’

1999 • 216 citations

Altered synaptophysin expression as a marker of synaptic pathology in schizophrenia

1995 • 216 citations

Levels of the growth-associated protein GAP-43 are selectively increased in association cortices in schizophrenia

1996 • 210 citations

Decreased synaptophysin in the medial temporal lobe in schizophrenia demonstrated using immunoautoradiography

1995 • 195 citations

Reduction of synapsin in the hippocampus of patients with bipolar disorder and schizophrenia

2002 • 187 citations

SNAP-25 deficit and hippocampal connectivity in schizophrenia

1998 • 172 citations

Hippocampal synaptic pathology in schizophrenia, bipolar disorder and major depression: a study of complexin mRNAs

2000 • 171 citations

Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics

1993 • 157 citations

Altered levels of the synaptosomal associated protein SNAP-25 in schizophrenia

1998 • 155 citations

Distinct patterns of expression of two VAMP genes within the rat brain

1990 • 154 citations

Abnormalities of SNARE Mechanism Proteins in Anterior Frontal Cortex in Severe Mental Illness

2002 • 150 citations

Cingulate cortex synaptic terminal proteins and neural cell adhesion molecule in schizophrenia

1997 • 146 citations

Altered levels of the synaptosomal associated protein SNAP-25 in hippocampus of subjects with mood disorders and schizophrenia

2001 • 142 citations

Presynaptic proteins in the prefrontal cortex of patients with schizophrenia and rats with abnormal prefrontal development

2003 • 124 citations

Entorhinal cortex pre-alpha cell clusters in schizophrenia: quantitative evidence of a developmental abnormality

2000 • 121 citations

Cerebellar synaptic protein expression in schizophrenia

2001 • 113 citations

Identification of two highly homologous presynaptic proteins distinctly localized at the dendritic and somatic synapses

1995 • 110 citations

Throttles and Dampers: Controlling the Engine of Membrane Fusion

1997 • 107 citations

Synaphin: A Protein Associated with the Docking/Fusion Complex in Presynaptic Terminals

1995 • 104 citations

The synaptic-vesicle-specific proteins rab3a and synaptophysin are reduced in thalamus and related cortical brain regions in schizophrenic brains

1999 • 103 citations

Synaptophysin gene expression in schizophrenia

2000 • 101 citations

Altered immunoreactivity of complexin protein in prefrontal cortex in severe mental illness

2002 • 99 citations

Lesions of hippocampal circuitry define synaptosomal-associated protein-25 (SNAP-25) as a novel presynaptic marker

1990 • 94 citations

Coloboma Hyperactive Mutant Mice Exhibit Regional and Transmitter‐Specific Deficits in Neurotransmission

1997 • 93 citations

Loss of synaptic but not cytoskeletal proteins in the cerebellum of chronic schizophrenics

2002 • 83 citations

Levels of mRNAs encoding synaptic vesicle and synaptic plasma membrane proteins in the temporal cortex of elderly schizophrenic patients

2000 • 79 citations

Protein–protein interactions in neurotransmitter release

2000 • 75 citations

Ultrastructural localization of SNAP‐25 within the rat spinal cord and peripheral nervous system

1995 • 67 citations

Synaptophysin and GAP-43 mRNA levels in the hippocampus of subjects with schizophrenia

2001 • 66 citations

Immunohistochemical distribution of the two isoforms of synaphin/complexin involved in neurotransmitter release: localization at the distinct central nervous system regions and synaptic types

1999 • 62 citations

Detection and quantification of hippocampal synaptophysin messenger RNA in schizophrenia using autoclaved, formalin-fixed, paraffin wax-embedded sections

1999 • 60 citations

Cellular and subcellular localization of syntaxin-like immunoreactivity in the rat striatum and cortex

1995 • 54 citations

Age-related abnormalities in expression of mRNAs encoding synapsin 1A, synapsin 1B, and synaptophysin in the temporal cortex of schizophrenics

1997 • 49 citations

A neural plasticity hypothesis of schizophrenia

1984 • 46 citations

A quantitative study on the expression of synapsin II and N-ethylmaleimide-sensitive fusion protein in schizophrenic patients

2001 • 44 citations

The Postmortem Brain in Psychiatric Research

2002 • 27 citations

The Neuropathology of Schizophrenia

2002 • 8 citations