Schizophrenia: Caused by a fault in programmed synaptic elimination during adolescence?

Dementia Praecox or the Group of Schizophrenias

1951 • 4,409 citations

Synaptic density in human frontal cortex — Developmental changes and effects of aging

1979 • 2,587 citations

Regional Development of the Brain in Early Life

1968 • 2,076 citations

THE NITROUS OXIDE METHOD FOR THE QUANTITATIVE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN: THEORY, PROCEDURE AND NORMAL VALUES 1

1948 • 2,051 citations

Peptidergic neurones

1980 • 1,523 citations

Selective stabilisation of developing synapses as a mechanism for the specification of neuronal networks

1976 • 1,444 citations

Quantitative growth and development of human brain

1973 • 1,439 citations

Sleep deprivation: Effect on sleep stages and EEG power density in man

1981 • 1,001 citations

Elimination of Synapses in the Developing Nervous System

1980 • 807 citations

Synaptogenesis in human visual cortex — evidence for synapse elimination during normal development

1982 • 747 citations

Age-related variations in evoked potentials to auditory stimuli in normal human subjects

1978 • 627 citations

Growth and Reshaping of Axons in the Establishment of Visual Callosal Connections

1981 • 598 citations

Efference Copy and Corollary Discharge: Implications for Thinking and Its Disorders*

1978 • 571 citations

Changes in sleep cycle patterns with age

1974 • 550 citations

BRAIN AND CONSCIOUS EXPERIENCE

1967 • 536 citations

The Postnatal Development of the Human Cerebral Cortex

1960 • 480 citations

EEG sleep patterns as a function of normal and pathological aging in man

1967 • 457 citations

Depletion of Brain Catecholamines: Failure of Ocular Dominance Shift After Monocular Occlusion in Kittens

1976 • 438 citations

Evidence that the early postnatal restriction of the cells of origin of the callosal projection is due to the elimination of axonal collaterals rather than to the death of neurons

1981 • 384 citations

The Genesis of the Eeg

1972 • 383 citations

NEURONAL DEATH AS A REGULATIVE MECHANISM IN THE CONTROL OF CELL NUMBER IN THE NERVOUS SYSTEM

1973 • 364 citations

ACQUIRED APHASIA IN CHILDREN

1965 • 341 citations

Human cerebral blood flow and oxygen consumption as related to aging

1956 • 332 citations

Electroencephalography (EEG) of human sleep : clinical applications

1974 • 319 citations

Ontogenetic changes in the projections of neocortical neurons

1982 • 272 citations

Local perfusion of noradrenaline maintains visual cortical plasticity

1978 • 272 citations

THE DENSITY OF SYNAPSES AND NEURONS IN NORMAL, MENTALLY DEFECTIVE AND AGEING HUMAN BRAINS

1975 • 223 citations

Electroencephalography (EEG) of Human Sleep: Clinical Applications

1974 • 168 citations

Genetic Expression in the Developing Brain

1983 • 167 citations

BILATERAL STUDIES OF CEREBRAL OXYGEN UPTAKE IN YOUNG AND AGED NORMAL SUBJECTS AND IN PATIENTS WITH ORGANIC DEMENTIA

1960 • 161 citations

Event-Related Brain Potentials: Comparison Between Children and Adults

1977 • 160 citations

Development and Aging in the Nervous System

1973 • 156 citations

Sleep Variables as a Function of Age in Man

1968 • 137 citations

The Aging Brain and Senile Dementia

1977 • 135 citations

CEREBRAL BLOOD FLOW AND METABOLISM IN PSYCHOSES OF SENILITY

1951 • 123 citations

The Functional Significance of Sleep with Particular Regard to the Brain Mechanisms Underlying Consciousness

1965 • 122 citations

Neuronal competition

1980 • 73 citations

Brain and Conscious Experience.

1967 • 69 citations

Changing concepts of the function of sleep: discovery of intense brain activity during sleep calls for revision of hypotheses as to its function.

1969 • 43 citations

Insect systems for the study of programmed neuronal death

1992 • 22 citations

THE DEMENTIA PRÆCOX-SCHIZOPHRENIA PROBLEM

1931 • 18 citations

The regulation of human sleep. Clues from its phenomenology.

1982 • 17 citations

The Post-Natal Development of the Human Cerebral Cortex. By J. Le Roy Conel. Cambridge, Mass., 1939. Pp. 114. 98 plates. Price 35s.

1939 • 16 citations

Ability of Blindfolded Children to Use Landmarks to Locate a Target

1964 • 3 citations