Modulation of Nuclear Protein Import

Nuclear Factor-κB — A Pivotal Transcription Factor in Chronic Inflammatory Diseases

1997 • 4,661 citations

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

1994 • 2,124 citations

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

1997 • 2,048 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK

1997 • 1,198 citations

Nucleocytoplasmic Transport

1996 • 1,071 citations

IMF-κB and Rel: Participants in a Multiform Transcriptional Regulatory System

1993 • 967 citations

Inhibition of Nuclear Translocation of Transcription Factor NF-κB by a Synthetic Peptide Containing a Cell Membrane-permeable Motif and Nuclear Localization Sequence

1995 • 923 citations

Nuclear protein import in permeabilized mammalian cells requires soluble cytoplasmic factors.

1990 • 909 citations

Isolation of a protein that is essential for the first step of nuclear protein import

1994 • 710 citations

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1994 • 523 citations

The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SW15

1991 • 501 citations

Synthetic peptides as nuclear localization signals

1986 • 472 citations

Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins.

1995 • 430 citations

Sequence requirements for synthetic peptide-mediated translocation to the nucleus.

1989 • 413 citations

Induction of nuclear transport with a synthetic peptide homologous to the SV40 T antigen transport signal

1986 • 394 citations

Block in Nuclear Localization of period Protein by a Second Clock Mutation, timeless

1994 • 360 citations

Nuclear protein import

1997 • 296 citations

Nuclear localization signals (NLS).

1993 • 249 citations

Identification of specific binding proteins for a nuclear location sequence

1989 • 219 citations

A GTPase Controlling Nuclear Trafficking: Running the Right Way or Walking RANdomly?

1996 • 211 citations

In vivo nuclear transport kinetics in Saccharomyces cerevisiae: a role for heat shock protein 70 during targeting and translocation.

1996 • 210 citations

Inhibition of Ran Guanosine Triphosphatase-Dependent Nuclear Transport by the Matrix Protein of Vesicular Stomatitis Virus

1997 • 175 citations

How Structural Features Influence the Biomembrane Permeability of Peptides

1996 • 170 citations

Differential Expression and Sequence-specific Interaction of Karyopherin α with Nuclear Localization Sequences

1997 • 168 citations

Differential roles of heat shock protein 70 in the in vitro nuclear import of glucocorticoid receptor and simian virus 40 large tumor antigen.

1994 • 114 citations

Toward the molecular dissection of protein import into nuclei

1996 • 112 citations

Identification of four nuclear transport signal-binding proteins that interact with diverse transport signals.

1989 • 101 citations

Selective nuclear transport of the Drosophila morphogen dorsal can be established by a signaling pathway involving the transmembrane protein Toll and protein kinase A.

1992 • 86 citations

The cell cycle-dependent nuclear import of v-Jun is regulated by phosphorylation of a serine adjacent to the nuclear localization signal.

1995 • 83 citations

Protein transport: The nonclassical ins and outs

1997 • 81 citations

Deoxyspergualin inhibits kappa light chain expression in 70Z/3 pre-B cells by blocking lipopolysaccharide-induced NF-kappa B activation.

1995 • 77 citations

A yeast protein that binds nuclear localization signals: purification localization, and antibody inhibition of binding activity.

1991 • 53 citations

Reduced nuclear import of human immunodeficiency virus type 1 preintegration complexes in the presence of a prototypic nuclear targeting signal

1994 • 47 citations

Comparison of diverse transport signals in synthetic peptide-induced nuclear transport

1990 • 43 citations

Nuclear Localization Signal of HIV-1 as a Novel Target for Therapeutic Intervention

1995 • 42 citations

Most Nuclear Proteins Are Imported by a Single Pathway

1993 • 35 citations

Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation.

1996 • 33 citations

Chapter 24 In Vivo Nuclear Transport Kinetics in Saccharomyces cerevisiae

1997 • 17 citations

Identification and characterization of nuclear location signal-binding proteins in nuclear envelopes

1991 • 8 citations