Gamma/Delta T Lymphocytes and Heat Shock Proteins

Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent.

1986 • 1,116 citations

Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium

1985 • 1,025 citations

Heat shock proteins and the immune response

1990 • 944 citations

Peptide Binding and Release by Proteins Implicated as Catalysts of Protein Assembly

1989 • 763 citations

Lymphocytes bearing antigen-specific γδ T-cell receptors accumulate in human infectious disease lesions

1989 • 592 citations

Specificity and function of T cells bearing γδ receptors

1988 • 570 citations

The T Cell Receptor

1987 • 554 citations

Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system.

1989 • 547 citations

Isolation of CD4-CD8-mycobacteria-reactive T lymphocyte clones from rheumatoid arthritis synovial fluid

1989 • 543 citations

Homing of a γδ thymocyte subset with homogeneous T-cell receptors to mucosal epithelia

1990 • 533 citations

Limited diversity of γδ antigen receptor genes of thy-1+ dendritic epidermal cells

1988 • 522 citations

Stimulation of a major subset of lymphocytes expressing T cell receptor γδ by an antigen derived from mycobacterium tuberculosis

1989 • 491 citations

The Structure, Function, and Molecular Genetics of the gamma/delta T Cell Receptor

1989 • 476 citations

Activation of γδ T Cells in the Primary Immune Response to Mycobacterium tuberculosis

1989 • 463 citations

Hydrogen peroxide-inducible proteins in Salmonella typhimurium overlap with heat shock and other stress proteins.

1986 • 442 citations

A functional T3 molecule associated with a novel heterodimer on the surface of immature human thymocytes

1986 • 430 citations

T cell stimulation by staphylococcal enterotoxins. Clonally variable response and requirement for major histocompatibility complex class II molecules on accessory or target cells.

1988 • 427 citations

Human γδ+ T cells respond to mycobacterial heat-shock protein

1989 • 417 citations

Diversity, rearrangement, and expression of murine T cell gamma genes

1986 • 405 citations

Intestinal intraepithelial lymphocytes are a distinct set of γδ T cells

1988 • 394 citations

A large fraction of human peripheral blood gamma/delta + T cells is activated by Mycobacterium tuberculosis but not by its 65-kD heat shock protein.

1990 • 331 citations

T Cells Against a Bacterial Heat Shock Protein Recognize Stressed Macrophages

1989 • 310 citations

Origin of Thy-1+ dendritic epidermal cells of adult mice from fetal thymic precursors

1990 • 306 citations

Recognition of a Peptide Antigen by Heat Shock--reactive γδ T Lymphocytes

1990 • 291 citations

Stress proteins may provide a link between the immune response to infection and autoimmunity

1989 • 264 citations

Monoclonal antibodies specific to native murine T-cell receptor gamma delta: analysis of gamma delta T cells during thymic ontogeny and in peripheral lymphoid organs.

1989 • 257 citations

Resident pulmonary lymphocytes expressing the γ/δ T-cell receptor

1989 • 253 citations

Recognition of heat shock proteins and γΔ cell function

1990 • 247 citations

A peptide binding protein having a role in antigen presentation is a member of the HSP70 heat shock family.

1989 • 246 citations

Primary responses of human T cells to mycobacteria: a frequent set of γ/δ T cells are stimulated by protease‐resistant ligands

1990 • 243 citations

T lymphocytes from healthy individuals with specificity to self-epitopes shared by the mycobacterial and human 65-kilodalton heat shock protein.

1989 • 237 citations

Structure and specificity of T cell receptor gamma/delta on major histocompatibility complex antigen-specific CD3+, CD4-, CD8- T lymphocytes.

1988 • 227 citations

Diversity of γδ T-cell receptors on murine intestinal intraepithelial lymphocytes

1989 • 217 citations

Enumeration of T cells reactive with Mycobacterium tuberculosis organisms and specific for the recombinant mycobacterial 64‐kDa protein

1987 • 216 citations

Distribution of T cells bearing different forms of the T cell receptor gamma/delta in normal and pathological human tissues.

1989 • 215 citations

Tissue localization and CD8 accessory molecule expression of T gamma delta cells in humans.

1989 • 189 citations

Different gamma delta T-cell receptors are expressed on thymocytes at different stages of development.

1989 • 183 citations

Gamma/delta T cell clones and natural killer cell clones mediate distinct patterns of non-major histocompatibility complex-restricted cytolysis.

1990 • 176 citations

Human TCR-gamma+/delta+, CD8+ T lymphocytes recognize tetanus toxoid in an MHC-restricted fashion.

1989 • 170 citations

Mitogen and lymphokine stimulation of heat shock proteins in T lymphocytes.

1988 • 168 citations

Sequential appearance of γ/δ‐ and α/β‐bearing T cells in the peritoneal cavity during an i.p. infection with Listeria monocytogenes

1990 • 162 citations

The λδ T cell receptor and class lb MHC-related proteins: Enigmatic molecules of immune recognition

1989 • 150 citations

Limited receptor repertoire in a mycobacteria-reactive subset of γδ T lymphocytes

1989 • 138 citations

Presence of Human 65 kD Heat Shock Protein (hsp) in Inflamed Joints and Subcutaneous Nodules of RA Patients

1990 • 135 citations

Self heat shock and gamma delta T-cell reactivity.

1990 • 103 citations

‘Nonspecific’ MHC-unrestricted killer cells and their receptors

1987 • 98 citations

Evidence for involvement of the gamma, delta T cell antigen receptor in cytotoxicity mediated by human alloantigen-specific T cell clones.

1989 • 91 citations

T-cell gamma gene is allelically but not isotypically excluded and is not required in known functional T-cell subsets.

1987 • 75 citations

T cell responses of normal individuals towards recombinant protein antigens of Mycobacterium tuberculosis

1988 • 74 citations

T-Cells, Stress Proteins, and Pathogenesis of Mycobacterial Infections

1990 • 68 citations

Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery.

1987 • 65 citations

A Mycobacterial Heat-Shock Protein-Responsive T Cell Clone Also Responds to the Homologous Human Heat-Shock Protein: A Possible Link between Infection and Autoimmunity

1991 • 62 citations

Lysis of interferon-γ activated Schwann cell by cross-reactive CD8⁺ ∝/β T cells with specificity for the mycobacterial 65 kd heat shock protein

1990 • 46 citations

Bacterial toxins as probes for the T-cell antigen receptor

1989 • 45 citations

Evidence that the T cell antigen receptor may not be involved in cytotoxicity mediated by gamma/delta and alpha/beta thymic cell lines.

1987 • 43 citations

Immunization against tuberculosis: what kind of vaccine?

1988 • 38 citations

Expression of C gamma 4 T cell receptors and lack of isotype exclusion by dendritic epidermal T cell lines.

1988 • 28 citations