Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent.

Experiments in molecular genetics

1972 • 28,260 citations

Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels

1971 • 11,879 citations

Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines

1981 • 2,042 citations

Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium

1985 • 1,025 citations

The effects of bacterial endotoxins on host mediation systems. A review.

1978 • 648 citations

Genetic engineering in Vivo using translocatable drug-resistance elements

1977 • 625 citations

The Role of Cell-Mediated Immunity in Bacterial Infections

1981 • 452 citations

Bactericidal and bacteriolytic activity of serum against gram-negative bacteria

1983 • 441 citations

Iron-Binding Catechols and Virulence in Escherichia coli

1973 • 403 citations

Non-smooth Mutants of Salmonella typhimurium: Differentiation by Phage Sensitivity and Genetic Mapping

1972 • 310 citations

MECHANISMS OF ACQUIRED RESISTANCE IN MOUSE TYPHOID

1966 • 288 citations

Association of adhesive, invasive, and virulent phenotypes of Salmonella typhimurium with autonomous 60-megadalton plasmids

1982 • 269 citations

Genetic control of the innate resistance of mice to Salmonella typhimurium: expression of the Ity gene in peritoneal and splenic macrophages isolated in vitro.

1983 • 257 citations

Hfr FORMATION DIRECTED BY Tn10

1979 • 226 citations

THE ROLE OF OXYGEN AND ITS DERIVATIVES IN MICROBIAL PATHOGENESIS AND HOST DEFENSE

1984 • 179 citations

Isolation of catalase-deficient Escherichia coli mutants and genetic mapping of katE, a locus that affects catalase activity

1984 • 165 citations

Genetic mapping of katG, a locus that affects synthesis of the bifunctional catalase-peroxidase hydroperoxidase I in Escherichia coli

1985 • 148 citations

Requirement of extracellular complement and immunoglobulin for intracellular killing of micro-organisms by human monocytes.

1979 • 138 citations

INTERACTION BETWEEN PHAGOCYTES AND PATHOGENIC MICROORGANISMS

1956 • 115 citations

Correlation between the presence of a fifty-megadalton plasmid in Salmonella dublin and virulence for mice

1983 • 115 citations

Genetic control of resistance to infection in mice.

1982 • 106 citations

Phagolysosome Formation, Cyclic Adenosine 3':5'-Monophosphate and the Fate of Salmonella typhimurium within Mouse Peritoneal Macrophages

1979 • 106 citations

Control of natural resistance to Salmonella typhimurium and Leishmania donovani in mice by closely linked but distinct genetic loci

1980 • 93 citations

Salmonellae activate complement differentially via the alternative pathway depending on the structure of their lipopolysaccharide O-antigen.

1983 • 86 citations

Regulation of catalase synthesis in Salmonella typhimurium

1975 • 76 citations

Predominant end-products of prophage Mu DNA transposition during the lytic cycle are replicon fusions

1981 • 71 citations

Transduction of Virulence within the Species Salmonella typhimurium

1956 • 47 citations

Elimination of Leishmania donovani amastigotes by activated macrophages

1981 • 43 citations

HISTIDINE MUTANTS REQUIRING ADENINE: SELECTION OF MUTANTS WITH REDUCED hisG EXPRESSION IN SALMONELLA TYPHIMURIUM

1979 • 40 citations

In vivo and in vitro characterization of virulence-deficient mutants of Vibrio cholerae

1979 • 36 citations

Utilization of 2,6-diaminopurine by Salmonella typhimurium

1980 • 6 citations