Apoptosis Induced by Ionizing Radiation

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1997 • 7,177 citations

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

1996 • 5,133 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

1993 • 2,911 citations

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.

1996 • 1,143 citations

Bax interacts with the permeability transition pore to induce permeability transition and cytochromecrelease in isolated mitochondria

1998 • 932 citations

Adaptive Response of Human Lymphocytes to Low Concentrations of Radioactive Thymidine

1984 • 817 citations

A new pathway for DNA repair in Escherichia coli

1977 • 705 citations

Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier.

1992 • 692 citations

Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux

1998 • 414 citations

Estimation of Life Times and Diffusion Distances of Radicals Involved in X-Ray-Induced DNA Strand Breaks or Killing of Mammalian Cells

1975 • 390 citations

Mammalian Cells Are Not Killed by DNA Single-Strand Breaks Caused by Hydroxyl Radicals from Hydrogen Peroxide

1985 • 305 citations

Prognostic significance of epidermal growth factor receptor in laryngeal squamous cell carcinoma

1996 • 260 citations

Expression and Regulation of Bcl-2, Bcl-xl, and Bax Correlate With p53 Status and Sensitivity to Apoptosis in Childhood Acute Lymphoblastic Leukemia

1997 • 212 citations

p53: the ultimate tumor suppressor gene?

1992 • 209 citations

Apoptosis and mitotic cell death: their relative contributions to normal-tissue and tumour radiation response

1997 • 156 citations

Epidermal growth factor receptor: An independent predictor of survival in astrocytic tumors given definitive irradiation

1996 • 93 citations

Mechanisms of DNA repair and their potential modification for radiotherapy

1986 • 87 citations

Cell-Cycle Regulation of Mammalian DNA Double-Strand-Break Repair

1997 • 80 citations

Irradiation of mitochondria initiates apoptosis in a cell free system

2001 • 58 citations

Radioresponsiveness at low doses: hyper-radiosensitivity and increased radioresistance in mammalian cells

1999 • 53 citations

Sequence of Metabolic Changes during X-Ray-Induced Apoptosis

1999 • 36 citations

Rhodamine 123: A useful probe for monitoring T cell activation

1995 • 33 citations

Probing chromatin structure in the early phases of apoptosis

1996 • 21 citations