Mammalian Cells Are Not Killed by DNA Single-Strand Breaks Caused by Hydroxyl Radicals from Hydrogen Peroxide

Estimation of life times and diffusion distances of radicals involved in x-ray-induced DNA strand breaks of killing of mammalian cells.

1975 • 420 citations

In vivo formation of single-strand breaks in DNA by hydrogen peroxide is mediated by the Haber-Weiss reaction

1984 • 350 citations

Chemical Radioprotection and Radiosensitization of Mammalian Cells Growingin Vitro

2012 • 316 citations

Some Biochemical Consequences of the Spatial Distribution of Ionizing Radiation-Produced Free Radicals

1981 • 281 citations

Glutathione Peroxidase Brought into Focus

1982 • 267 citations

Unusual copper-induced sensitization of the biological damage due to superoxide radicals.

1981 • 240 citations

Molecular Mechanisms of Radiation-Induced Damage to Nucleic Acids

1975 • 240 citations

Model of Tracks of Ionizing Radiations for Radical Reaction Mechanisms

1966 • 228 citations

Chemical analysis of DNA alterations

1968 • 222 citations

Comparison of the effects of hydrogen peroxide and X-ray irradiation on toxicity, mutation, and DNA damage/repair in mammalian cells (V-79)

1981 • 163 citations

Macromolecular Repair and Free Radical Scavenging in the Protection of Bacteria against X-Rays

1965 • 139 citations

Counter-Ion Condensation and System Dimensionality

1983 • 126 citations

Correlation between cytotoxic effect of hydrogen peroxide and the yield of DNA strand breaks in cells of different species

1984 • 124 citations

On the Use of OH · Scavengers in Biological Systems

1984 • 100 citations

ACTION OF HYDROGEN PEROXIDE ON HUMAN FIBROBLAST IN CULTURE

1979 • 99 citations

Radiation resistance and the CuZn superoxide dismutase, Mn superoxide dismutase, catalase, and glutathione peroxidase activities of seven human cell lines.

1984 • 65 citations

Deoxyribonucleic acid-protein and deoxyribonucleic acid interstrand crosslinks induced in isolated chromatin by hydrogen peroxide and ferrous ethylenediaminetetraacetate chelates

1982 • 60 citations

A quantitative assay of deoxyribonucleic acid strand breaks and their repair in mammalian cells

1982 • 50 citations

Alteration of bleomycin cytotoxicity by glutathione depletion or elevation

1984 • 50 citations

DNA repair and cell repair: Are they related?

1979 • 45 citations

Effects of inhibitors of DNA strand break repair on HeLa cell radiosensitivity.

1984 • 37 citations

Dégradation du DNA par H₂O₂ en présence d'ions Cu⁺⁺, Fe⁺⁺ et Fe⁺⁺⁺

1969 • 23 citations

Detection and Fixation of Radiation-Produced Peroxide by Enzymes

1963 • 18 citations

[Relationship between temperature and catalase kinetics under conditions of substrate inactivation].

1976 • 1 citations