The Cytokine Network of Wallerian Degeneration: Tumor Necrosis Factor-α, Interleukin-1α, and Interleukin-1β

Degeneration and Regeneration of the Nervous System.

1929 • 2,924 citations

Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth

1994 • 1,123 citations

A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration

1994 • 1,068 citations

Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system

2000 • 1,053 citations

Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve

1987 • 1,000 citations

The macrophage response to central and peripheral nerve injury. A possible role for macrophages in regeneration.

1987 • 596 citations

Nerve Injury, Axonal Degeneration and Neural Regeneration: Basic Insights

1999 • 553 citations

Schwann cells produce tumor necrosis factor alpha: expression in injured and non-injured nerves

1996 • 357 citations

Macrophage dependence of peripheral sensory nerve regeneration: Possible involvement of nerve growth factor

1991 • 296 citations

Basement Membrane and Repair of Injury to Peripheral Nerve: Defining a Potential Role for Macrophages, Matrix Metalloproteinases, and Tissue Inhibitor of Metalloproteinases-1

1996 • 242 citations

Peripheral nerve injury induces Schwann cells to express two macrophage phenotypes: phagocytosis and the galactose-specific lectin MAC-2

1994 • 217 citations

Endogenous interleukin‐6 contributes to hypersensitivity to cutaneous stimuli and changes in neuropeptides associated with chronic nerve constriction in mice

1999 • 207 citations

Neurotrophins, nociceptors, and pain

1999 • 190 citations

Disruption of the Gene for the Myelin-Associated Glycoprotein Improves Axonal Regrowth along Myelin in C57BL/Wlds Mice

1996 • 186 citations

Tumor necrosis factor stimulates the synthesis and secretion of biologically active nerve growth factor in non-neuronal cells.

1993 • 168 citations

Macrophage and microglial responses to cytokines in vitro: Phagocytic activity, proteolytic enzyme release, and free radical production

1998 • 159 citations

Serial Determination of Tumor Necrosis Factor-Alpha Content in Rat Sciatic Nerve after Chronic Constriction Injury

1999 • 152 citations

Interleukin 6 in Intact and Injured Mouse Peripheral Nerves

1996 • 139 citations

Anti-macrophage CR3 antibody blocks myelin phagocytosis by macrophages in vitro

1990 • 134 citations

NI-35/250/nogo-a: A neurite growth inhibitor restricting structural plasticity and regeneration of nerve fibers in the adult vertebrate CNS

2000 • 126 citations

Reduced Hyperalgesia in Nerve-Injured WLD Mice: Relationship to Nerve Fiber Phagocytosis, Axonal Degeneration, and Regeneration in Normal Mice

1996 • 124 citations

Receptor-mediated phagocytosis of myelin by macrophages and microglia: Effect of opsonization and receptor blocking agents

1996 • 121 citations

Granulocyte macrophage colony stimulating factor produced in lesioned peripheral nerves induces the up-regulation of cell surface expression of MAC-2 by macrophages and Schwann cells.

1996 • 114 citations

Interleukin-1 activity in lesioned peripheral nerve

1992 • 114 citations

Galectin-3/MAC-2 in Experimental Allergic Encephalomyelitis

1999 • 96 citations

Deficient activation of microglia during optic nerve degeneration

1996 • 92 citations

Influence of injury and cytokines on synthesis of monocyte chemoattractant protein‐1 mRNA in peripheral nervous tissue

2001 • 88 citations

The cytokine network of Wallerian degeneration: IL‐10 and GM‐CSF

1998 • 78 citations

Distinct Inflammatory Stimuli Induce Different Patterns of Myelin Phagocytosis and Degradation in Recruited Macrophages

2001 • 43 citations

Modulation (Inhibition and Augmentation) of Complement Receptor-3-Mediated Myelin Phagocytosis

2001 • 42 citations

Sequential expression of mRNA for proinflammatory cytokines and interleukin‐10 in the rat peripheral nervous system: Comparison between immune‐mediated demyelination and wallerian degeneration

1998 • 4 citations