Making Membranes Green: Construction and Characterization of GFP-Fusion Proteins Targeted to Discrete Plasma Membrane Domains

Lipid rafts and signal transduction

2000 • 6,079 citations

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

1992 • 1,046 citations

Membrane Compartmentation Is Required for Efficient T Cell Activation

1998 • 925 citations

Aggregation of Lipid Rafts Accompanies Signaling via the T Cell Antigen Receptor

1999 • 800 citations

Myristylation and palmitylation of Src family members: The fats of the matter

1994 • 694 citations

Cysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae.

1994 • 389 citations

The Ick tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain

1989 • 362 citations

Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains.

1996 • 312 citations

Palmitylation of an amino-terminal cysteine motif of protein tyrosine kinases p56lck and p59fyn mediates interaction with glycosyl-phosphatidylinositol-anchored proteins.

1993 • 259 citations

Cytoskeletal Polarization of T Cells Is Regulated by an Immunoreceptor Tyrosine-based Activation Motif–dependent Mechanism

1998 • 247 citations

Monitoring Agonist-induced Phospholipase C Activation in Live Cells by Fluorescence Resonance Energy Transfer

2001 • 237 citations

Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes.

1994 • 180 citations

Effects of p56lck deficiency on the growth and cytolytic effector function of an interleukin-2-dependent cytotoxic T-cell line.

1992 • 175 citations

N-Terminal Protein Acylation Confers Localization to Cholesterol, Sphingolipid-enriched Membranes But Not to Lipid Rafts/Caveolae

2001 • 123 citations

Optical microscopy: emerging methods and applications

1993 • 108 citations

Palmitoylation of Either Cys-3 or Cys-5 Is Required for the Biological Activity of the Lck Tyrosine Protein Kinase

1995 • 98 citations

Structural studies of receptor binding by cholera toxin mutants

1997 • 96 citations

Signals Determining Protein Tyrosine Kinase and Glycosyl-Phosphatidylinositol-Anchored Protein Targeting to a Glycolipid-Enriched Membrane Fraction

1994 • 88 citations

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

1992 • 84 citations

Glycolipid-Enriched Membrane Domains Are Assembled into Membrane Patches by Associating with the Actin Cytoskeleton

2001 • 69 citations

Amino-Terminal Palmitate or Polybasic Domain Can Provide Required Second Signal to Myristate for Membrane Binding of P56lck

1995 • 47 citations

Vesicle Trafficking and Cell Surface Membrane Patchiness

2001 • 42 citations

Making Genes Green: Creating Green Fluorescent Protein (GFP) Fusions with Blunt-End PCR Products

1998 • 15 citations