Construction and Characterization of Viable Deletion Mutants of Simian Virus 40 Lacking Sequences near the 3′ End of the Early Region

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

A new method for sequencing DNA.

1977 • 7,941 citations

T antigen is bound to a host protein in SY40-transformed cells

1979 • 2,378 citations

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1979 • 1,830 citations

Complete nucleotide sequence of SV40 DNA

1978 • 1,050 citations

The Genome of Simian Virus 40

1978 • 948 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

Spliced early mRNAs of simian virus 40

1978 • 817 citations

DNA Tumor Viruses

1982 • 550 citations

The binding site on SV40 DNA for a T antigen-related protein

1978 • 542 citations

Function of simian virus 40 gene A in transforming infection

1975 • 447 citations

Regulation of tumor antigen synthesis by simain virus 40 gene A

1975 • 435 citations

Coding potential and regulatory signals of the polyoma virus genome

1980 • 369 citations

Construction and analysis of viable deletion mutants of simian virus 40

1976 • 355 citations

Simian virus 40 functions required for the establishment and maintenance of malignant transformation

1975 • 354 citations

INFECTION OF HUMAN AND SIMIAN TISSUE CULTURES WITH ROUS SARCOMA VIRUS

1964 • 354 citations

Role of simian virus 40 gene A function in maintenance of transformation

1975 • 321 citations

Simian virus 40 gene A function and maintenance of transformation

1975 • 301 citations

Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells

1978 • 284 citations

Autoregulation of simian virus 40 gene A by T antigen.

1976 • 248 citations

Organization and expression of early genes of simian virus 40

1978 • 238 citations

Complementation and transformation by temperature-sensitive mutants of polyoma virus

1969 • 212 citations

Temperature-sensitive growth regulation in one type of transformed rat cells induced by the tsa mutant of polyoma virus

1977 • 211 citations

Temperature-Sensitive Mutants of Simian Virus 40: Infection of Permissive Cells

1971 • 204 citations

Defective simian virus 40 genomes: Isolation and growth of individual clones

1974 • 201 citations

CELL-TRANSFORMING ABILITY OF A TEMPERATURE-SENSITIVE MUTANT OF POLYOMA VIRUS

1965 • 198 citations

Enhancement of Adenovirus Growth in African Green Monkey Kidney Cell Cultures by SV40

1964 • 190 citations

Enzymatic activities associated with a purified simian virus 40 T antigen-related protein

1979 • 189 citations

A defined subgenomic fragment of in vitro synthesized Moloney sarcoma virus DNA can induce cell transformation upon transfection

1979 • 187 citations

The SV40 a gene product is required for the production of a 54,000 MW cellular tumor antigen

1979 • 179 citations

A map of temperature-sensitive mutants of simian virus 40

1975 • 178 citations

Complementation Analysis of Simian Virus 40 Mutants

1974 • 174 citations

Characterization of the Autoregulation of Simian Virus 40 Gene A

1977 • 168 citations

Enhancement of Adenovirus Plaque Formation on HeLa Cells by Magnesium Chloride

1970 • 164 citations

The nucleotide sequence and genome organization of the polyoma early region: Extensive nucleotide and amino acid homology with SV40

1979 • 162 citations

Physical and Genetic Characterization of Deletion Mutants of Simian Virus 40 Constructed In Vitro

1977 • 157 citations

New region of the simian virus 40 genome required for efficient viral transformation.

1978 • 153 citations

An Exonuclease Induced by Bacteriophage λ

1967 • 151 citations

Temperature-sensitive mutants of polyoma virus

1969 • 148 citations

Initiation and maintenance of cell transformation by simian virus 40: a viral genetic property.

1975 • 138 citations

A temperature-sensitive mutant of simian virus 40 affecting transforming ability

1973 • 128 citations

Mutants of Simian Virus 40 Differing in Plaque Size, Oncogenicity, and Heat Sensitivity

1966 • 126 citations

Subcellular Localization of Simian Virus 40 Large Tumor Antigen

1979 • 125 citations

IMPROVED METHOD FOR STAINING CELL MONOLAYERS FOR VIRUS PLAQUE COUNTS

1959 • 116 citations

New classes of viable deletion mutants in the early region of polyoma virus

1979 • 116 citations

Relationship of Replication and Transcription of Simian Virus 40 DNA

1973 • 114 citations

Transformation of BALB/c-3T3 cells by tsA mutants of simian virus 40: temperature sensitivity of the transformed phenotype and retransofrmation by wild-type virus

1978 • 114 citations

Mapping of Simian Virus 40 Early Functions on the Viral Chromosome

1973 • 109 citations

Studies of Nondefective Adenovirus 2-Simian Virus 40 Hybrid Viruses V. Isolation of Additional Hybrids Which Differ in Their Simian Virus 40-Specific Biological Properties

1973 • 107 citations

Large and small tumor antigens from simian virus 40 have identical amino termini mapping at 0.65 map units.

1978 • 105 citations

Biology of simian virus 40 (SV40) transplantation antigen (TrAg)

1980 • 99 citations

Biochemical procedure for production of small deletions in simian virus 40 DNA.

1975 • 93 citations

Nuclear preparations of SV40-transformed cells contain tumors-pecific transplantation antigen activity

1977 • 93 citations

Simian Virus 40 Mutants with Deletions at the 3′ End of the Early Region Are Defective in Adenovirus Helper Function

1979 • 90 citations

Biology of simian virus 40 (SV40) transplantation antigen (TrAg)

1979 • 82 citations

Antigenic and Immunogenic Characteristics of Nuclear and Membrane-Associated Simian Virus 40 Tumor Antigen

1980 • 77 citations

Simian virus 40 small t antigen is not required for the maintenance of transformation but may act as a promoter (cocarcinogen) during establishment of transformation in resting rat cells

1979 • 76 citations

Characterization of a temperature-sensitive mutant of polyoma virus

1970 • 76 citations

The Polyoma virus 100K large T-antigen is not required for the maintenance of transformation

1980 • 73 citations

Conditional lethal mutants of adenovirus type 2-simian virus 40 hybrids. II. Ad2+ND1 host-range mutants that synthesize fragments of the Ad2+ND1 30K protein

1976 • 69 citations

Transformation of rat embryo fibroblasts by cloned polyoma virus DNA fragments containing only part of the early region.

1980 • 68 citations

Growth control in simian virus 40-transformed rat cells: temperature-independent expression of the transformed phenotype in tsA transformants derived by agar selection

1978 • 67 citations

Characterization of a fused protein specified by the adenovirus type 2-simian virus 40 hybrid Ad2+ND1 dp2

1979 • 64 citations

Separation of lytic and transforming functions of the simian virus 40 A region: two mutants which are temperature sensitive for lytic functions have opposite effects on transformation

1981 • 57 citations

Growth state of the cell early after infection with simian virus 40 determines whether the maintenance of transformation will be A-gene dependent or independent

1979 • 54 citations

Effect of alkylation on the physical properties of simian virus 40 T-antigen species

1979 • 52 citations

Expression of simian virus 40 early genes in transformed rat cells is correlated with maintenance of the transformed phenotype

1978 • 49 citations

Interaction of partially purified simian virus 40 T antigen with circular viral DNA molecules.

1975 • 40 citations

Measurements of the molecular size of the simian virus 40 large T antigen

1978 • 40 citations

The sequences between 0.59 and 0.54 map units on SV40 DNA code for the unique region of small t antigen

1978 • 36 citations

Simian virus 40-associated small RNA: mapping on the simian virus 40 genome and characterization of its synthesis

1980 • 35 citations

Nucleotide sequence analysis of two simian virus 40 mutants with deletions in the region coding for the carboxyl terminus of the T antigen

1979 • 34 citations

A Third Splice Site in SV40 Early mRNA

1980 • 30 citations

Biology of SV40 transplantation antigen (TrAg)

1976 • 27 citations

Biology of simian virus 40 (SV40) transplantation antigen (TrAg) VII. Induction of SV40 TrAg in nonpermissive mouse cells by early viable SV40 deletion (0.54/0.59) mutants

1980 • 26 citations

Anchorage independence: Analysis of factors affecting the growth and colony formation of wild-type and dl mutant SV40-transformed lines

1979 • 22 citations

Polyoma large tumor antigen is not required for tumorigenesis mediated by viral DNA.

1980 • 22 citations

Simian virus 40 T-antigen: identification of tryptic peptides in the C-terminal region and definition of the reading frame

1980 • 21 citations

Effect of a tsA mutation of simian virus 40 late gene expression: variations between host cell lines

1980 • 20 citations

Transformation of BALB/c-3T3 cells by tsA mutants of simian virus 40: effect of transformation technique on the transformed phenotype

1980 • 19 citations

SV40 Mutant tsA1499 Is Heat-sensitive for Lytic Growth but Generates Cold-sensitive Rat-cell Transformants

1980 • 19 citations