Concept of lymphoid versus myeloid dendritic cell lineages revisited: both CD8α− and CD8α+dendritic cells are generated from CD4lowlymphoid-committed precursors

Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation.

1996 • 2,032 citations

Activation of human dendritic cells through CD40 cross-linking.

1994 • 1,351 citations

Distinct dendritic cell subsets differentially regulate the class of immune responseinvivo

1999 • 1,013 citations

In Vivo Microbial Stimulation Induces Rapid CD40 Ligand–independent Production of Interleukin 12 by Dendritic Cells and their Redistribution to T Cell Areas

1997 • 937 citations

Differentiation of Phagocytic Monocytes into Lymph Node Dendritic Cells In Vivo

1999 • 904 citations

CD4 and CD8 Expression by Dendritic Cell Subtypes in Mouse Thymus and Spleen

2000 • 812 citations

Regulation of dendritic cell numbers and maturation by lipopolysaccharide in vivo.

1996 • 800 citations

Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor population

1993 • 673 citations

A subclass of dendritic cells kills CD4 T cells via Fas/Fas-ligand-induced apoptosis.

1996 • 653 citations

The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells.

1992 • 642 citations

Dendritic cell subtypes in mouse lymphoid organs: cross-correlation of surface markers, changes with incubation, and differences among thymus, spleen, and lymph nodes.

1997 • 524 citations

Developmental pathways of dendritic cells in vivo: distinct function, phenotype, and localization of dendritic cell subsets in FLT3 ligand-treated mice.

1997 • 455 citations

RelB Is Essential for the Development of Myeloid-Related CD8α− Dendritic Cells but Not of Lymphoid-Related CD8α+ Dendritic Cells

1998 • 443 citations

Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progeny.

1996 • 405 citations

Interleukin 12–dependent Interferon γ Production by CD8α+Lymphoid Dendritic Cells

1999 • 340 citations

Developmental potential of the earliest precursor cells from the adult mouse thymus.

1991 • 294 citations

Heterogeneity of Mouse Spleen Dendritic Cells: In Vivo Phagocytic Activity, Expression of Macrophage Markers, and Subpopulation Turnover

1998 • 261 citations

The influence of granulocyte/macrophage colony‐stimulating factor on dendritic cell levels in mouse lymphoid organs

1997 • 247 citations

Definition of Dendritic Cell Subpopulations Present in the Spleen, Peyer’s Patches, Lymph Nodes, and Skin of the Mouse

1999 • 244 citations

A subclass of dendritic cells regulates the response of naive CD8 T cells by limiting their IL-2 production.

1996 • 238 citations

Cell-Autonomous Defects in Dendritic Cell Populations of Ikaros Mutant Mice Point to a Developmental Relationship with the Lymphoid Lineage

1997 • 221 citations

Dendritic Cell Development: Multiple Pathways to Nature's Adjuvants

1997 • 217 citations

PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells

2000 • 190 citations

Antigen-pulsed CD8α+ Dendritic Cells Generate an Immune Response after Subcutaneous Injection without Homing to the Draining Lymph Node

1999 • 161 citations

Expression of pT mRNA in a Committed Dendritic Cell Precursor in the Human Thymus

1999 • 153 citations

Role of CD8α+ and CD8α− dendritic cells in the induction of primary immune responses in vivo

1999 • 151 citations

Notch1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells

2000 • 143 citations

Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant mice

1999 • 82 citations

CTL priming by CD8+ and CD8– dendritic cellsin vivo

1999 • 76 citations

IL-12 Acts Selectively on CD8α− Dendritic Cells to Enhance Presentation of a Tumor Peptide In Vivo

1999 • 53 citations

Cross-Linking of Membrane CD43 Mediates Dendritic Cell Maturation

1999 • 51 citations

Does the IL-2 receptor alpha chain induced on dendritic cells have a biological function?

1998 • 46 citations

The nature of the signals regulating CD8 T cell proliferative responses to CD8α⁺ or CD8α⁻ dendritic cells

1997 • 42 citations