Maintenance of NF-κB Activity Is Dependent on Protein Synthesis and the Continuous Presence of External Stimuli

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

1987 • 2,149 citations

Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism

1986 • 2,043 citations

Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

1989 • 1,660 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

1990 • 900 citations

Cloning of the p50 DNA binding subunit of NF-κB: Homology to rel and dorsal

1990 • 870 citations

Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone.

1989 • 726 citations

Identification of two types of tumor necrosis factor receptors on human cell lines by monoclonal antibodies.

1990 • 678 citations

Protein-Binding Sites in Ig Gene Enhancers Determine Transcriptional Activity and Inducibility

1987 • 619 citations

Activation of HIV gene expression during monocyte differentiation by induction of NF-kB

1989 • 590 citations

A 65-kappaD subunit of active NF-kappaB is required for inhibition of NF-kappaB by I kappaB.

1989 • 517 citations

Protein kinase C activation by diacylglycerol second messengers

1986 • 498 citations

The same inducible nuclear proteins regulates mitogen activation of both the interleukin-2 receptor-alpha gene and type 1 HIV

1988 • 427 citations

Two Different Cell Types have Different Major Receptors for Human Tumor Necrosis Factor (TNFα)

1989 • 368 citations

Double-stranded RNA activates binding of NF-kappa B to an inducible element in the human beta-interferon promoter.

1989 • 317 citations

Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro.

1988 • 309 citations

Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter.

1988 • 308 citations

NF-κB, KBF1, dorsal, and related matters

1990 • 267 citations

Protein kinase C-independent activation of nuclear factor kappa B by tumor necrosis factor.

1990 • 193 citations

The activation of protein kinase C by biologically active lipid moieties of lipopolysaccharide.

1984 • 180 citations

Tumor necrosis factors-alpha and -beta bind to the same two types of tumor necrosis factor receptors and maximally activate the transcription factor NF-kappa B at low receptor occupancy and within minutes after receptor binding.

1990 • 132 citations

HIV-1, HTLV-1 and normal T-cell growth: transcriptional strategies and surprises

1989 • 126 citations

Tumor necrosis factor-alpha activation of the IL-2 receptor-alpha gene involves the induction of kappa B-specific DNA binding proteins.

1989 • 98 citations