A New Orphan Member of the Nuclear Hormone Receptor Superfamily That Interacts with a Subset of Retinoic Acid Response Elements

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

1990 • 3,462 citations

Current protocols in molecular biology

1988 • 2,473 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling

1992 • 1,514 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells

1987 • 1,189 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily.

1990 • 1,044 citations

Identification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene

1990 • 1,018 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Determinants of target gene specificity for steroid/thyroid hormone receptors

1989 • 954 citations

The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene.

1992 • 903 citations

Multiplicity generates diversity in the retinoic acid signalling pathways

1992 • 836 citations

Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors.

1992 • 829 citations

Expression of a retinoic acid response element-hsplacZ transgene defines specific domains of transcriptional activity during mouse embryogenesis.

1991 • 730 citations

An LFA-3 cDNA encodes a phospholipid-linked membrane protein homologous to its receptor CD2

1987 • 699 citations

A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

1991 • 672 citations

Evolution of the nuclear receptor gene superfamily.

1992 • 662 citations

The orientation and spacing of core DNA-binding motifs dictate selective transcriptional responses to three nuclear receptors

1991 • 603 citations

Function of retinoic acid receptor γ in the mouse

1993 • 595 citations

Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid

1992 • 583 citations

Dopaminergic and Ligand-Independent Activation of Steroid Hormone Receptors

1991 • 577 citations

Identification of the DNA Binding Site for NGFI-B by Genetic Selection in Yeast

1991 • 566 citations

High postnatal lethality and testis degeneration in retinoic acid receptor alpha mutant mice.

1993 • 541 citations

Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element

1989 • 507 citations

Identification of a tHyroid Hormone Receptor That Is Pituitary-Specific

1989 • 493 citations

Characterization of an autoregulated response element in the mouse retinoic acid receptor type beta gene.

1990 • 487 citations

The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily.

1990 • 483 citations

H-2RIIBP (RXR beta) heterodimerization provides a mechanism for combinatorial diversity in the regulation of retinoic acid and thyroid hormone responsive genes.

1992 • 480 citations

RXR alpha, a promiscuous partner of retinoic acid and thyroid hormone receptors.

1992 • 446 citations

Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor

1987 • 434 citations

All-trans and 9-cis retinoic acid induction of CRABPII transcription is mediated by RAR-RXR heterodimers bound to DR1 and DR2 repeated motifs

1992 • 417 citations

Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid.

1991 • 395 citations

Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing.

1991 • 390 citations

Repression of transcription mediated at a thyroid hormone response element by the v-erb-A oncogene product

1989 • 387 citations

Two amino acids within the knuckle of the first zinc finger specify DNA response element activation by the glucocorticoid receptor

1989 • 358 citations

Transcriptional regulation of human apolipoprotein genes ApoB, ApoCIII, and ApoAII by members of the steroid hormone receptor superfamily HNF-4, ARP-1, EAR-2, and EAR-3.

1992 • 325 citations

Dual regulatory role for thyroid-hormone receptors allows control of retinoic-acid receptor activity

1989 • 308 citations

A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter.

1991 • 240 citations

Mutations of the Rat Growth Hormone Promoter which Increase and Decrease Response to Thyroid Hormone Define a Consensus Thyroid Hormone Response Element

1989 • 240 citations

Dopamine Activation of an Orphan of the Steroid Receptor Superfamily

1991 • 217 citations

Mouse retinoic acid receptor alpha 2 isoform is transcribed from a promoter that contains a retinoic acid response element.

1991 • 212 citations

Normal development and growth of mice carrying a targeted disruption of the alpha 1 retinoic acid receptor gene.

1993 • 192 citations

CAT vectors for analysis of eukaryotic promoters and enhancers

1986 • 184 citations

Functional characterization of the rat growth hormone promoter elements required for induction by thyroid hormone with and without a co-transfected β type thyroid hormone receptor

1989 • 177 citations

Transgenic indicator mice for studying activated retinoic acid receptors during development.

1992 • 170 citations

An everted repeat mediates retinoic acid induction of the gamma F-crystallin gene: evidence of a direct role for retinoids in lens development.

1993 • 157 citations

Trans-activation by thyroid hormone receptors: functional parallels with steroid hormone receptors.

1989 • 154 citations

The late retinoic acid induction of laminin B1 gene transcription involves RAR binding to the responsive element.

1991 • 152 citations

Retinoic acid affects the expression of nuclear retinoic acid receptors in tissues of retinol-deficient rats.

1991 • 126 citations

Domains regulating transcriptional activity of the inducible orphan receptor NGFI-B.

1992 • 110 citations

Functional characterization of a natural retinoic acid responsive element.

1991 • 100 citations

Heterodimerization of thyroid hormone (TH) receptor with H-2RIIBP (RXR beta) enhances DNA binding and TH-dependent transcriptional activation.

1992 • 88 citations

Transcriptional Activation by Nur77, a Growth Factor-lnducible Member of the Steroid Hormone Receptor Superfamily

1991 • 76 citations

Hepatocyte nuclear factor-4 activates medium chain acyl-CoA dehydrogenase gene transcription by interacting with a complex regulatory element

1993 • 66 citations

Identification of a novel retinoid-responsive element in the promoter region of the medium chain acyl-coenzyme A dehydrogenase gene.

1992 • 60 citations

A quick procedure for purification of functional recombinant proteins over-expressed inE.Coli

1991 • 58 citations