Translation to Near the Distal End of the Penultimate Exon Is Required for Normal Levels of Spliced Triosephosphate Isomerase mRNA

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Genomic sequencing.

1984 • 8,343 citations

Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

1977 • 2,408 citations

A survey on intron and exon lengths

1988 • 569 citations

Splice site selection, rate of splicing, and alternative splicing on nascent transcripts.

1988 • 539 citations

Interference of nonsense mutations with eukaryotic messenger RNA stability.

1979 • 454 citations

Unstable β-globin mRNA in mRNA-deficient β0 thalassemia

1981 • 267 citations

Nonsense mutations in the human beta-globin gene affect mRNA metabolism.

1988 • 229 citations

In vivo splicing products of the rabbit β-globin pre-mRNA

1984 • 209 citations

Consequences of frameshift mutations at the immunoglobulin heavy chain locus of the mouse.

1985 • 193 citations

Nonsense and frameshift mutations in beta 0-thalassemia detected in cloned beta-globin genes.

1981 • 129 citations

Effect of premature termination of translation on mRNA stability depends on the site of ribosome release.

1987 • 127 citations

mRNA-deficint β^°-thaladssemia results from a single nucleotide deletion

1982 • 111 citations

Intranuclear defect in beta-globin mRNA accumulation due to a premature translation termination codon

1984 • 102 citations

Structure and expression of a cloned β°thalassaemic globin gene

1981 • 85 citations

Beta O-39 thalassemia gene: a premature termination codon causes beta- mRNA deficiency without affecting cytoplasmic beta-mRNA stability

1984 • 82 citations

The Instability of Messenger RNA in Bacteria

1986 • 75 citations

New amber mutation in a beta-thalassemic gene with nonmeasurable levels of mutant messenger RNA in vivo.

1988 • 74 citations

Novel metabolism of several beta zero-thalassemic beta-globin mRNAs in the erythroid tissues of transgenic mice.

1989 • 56 citations

Transcriptional Regulatory Sequences of the Housekeeping Gene for Human Triosephosphate Isomerase

1989 • 51 citations

A β°-thalassemic β-globin RNA that is labile in bone marrow cells is relatively stable in HeLa cells

1985 • 27 citations

Analysis of gene expression using episomal mouse dihydrofolate reductase minigenes

1988 • 18 citations

Delayed processing/export of messenger RNA under conditions of reduced protein synthesis

1988 • 12 citations