Epithelial Ca2+ entry channels: transcellular Ca2+ transport and beyond

Calcium's Role in Mechanotransduction during Muscle Development

2014 • 14,293 citations

Tree View: An application to display phylogenetic trees on personal computers

1996 • 10,369 citations

The capsaicin receptor: a heat-activated ion channel in the pain pathway

1997 • 8,634 citations

Down-Regulation of Na⁺/K⁺ATPase Activity by Human Parvovirus B19 Capsid Protein VP1

2013 • 8,607 citations

The versatility and universality of calcium signalling

2000 • 5,407 citations

A capsaicin-receptor homologue with a high threshold for noxious heat

1999 • 1,547 citations

Store depletion and calcium influx

1997 • 1,422 citations

Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor

2000 • 1,348 citations

Molecular characterization of the drosophila trp locus: A putative integral membrane protein required for phototransduction

1989 • 1,119 citations

OTRPC4, a nonselective cation channel that confers sensitivity to extracellular osmolarity

2000 • 982 citations

A Heat-Sensitive TRP Channel Expressed in Keratinocytes

2002 • 913 citations

LTRPC7 is a Mg·ATP-regulated divalent cation channel required for cell viability

2001 • 900 citations

TRPV3 is a calcium-permeable temperature-sensitive cation channel

2002 • 870 citations

1,25-Dihydroxyvitamin D3 increases the expression of the CaT1 epithelial calcium channel in the Caco-2 human intestinal cell line.

2001 • 849 citations

TRPV3 is a temperature-sensitive vanilloid receptor-like protein

2002 • 811 citations

TRP-PLIK, a Bifunctional Protein with Kinase and Ion Channel Activities

2001 • 714 citations

Extracellular Ca2+ sensing, regulation of parathyroid cell function, and role of Ca2+ and other ions as extracellular (first) messengers

1991 • 690 citations

OSM-9, A Novel Protein with Structural Similarity to Channels, Is Required for Olfaction, Mechanosensation, and Olfactory Adaptation inCaenorhabditis elegans

1997 • 621 citations

Molecular Cloning and Characterization of a Channel-like Transporter Mediating Intestinal Calcium Absorption

1999 • 610 citations

Molecular Identification of the Apical Ca2+Channel in 1,25-Dihydroxyvitamin D3-responsive Epithelia

1999 • 587 citations

Duodenal calcium absorption in vitamin D receptor–knockout mice: Functional and molecular aspects

2001 • 579 citations

Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I

1999 • 473 citations

Subcellular distribution of Ca2+ release channels underlying Ca2+ waves and oscillations in exocrine pancreas

1993 • 357 citations

Calcium-dependent enzyme activation and vacuole formation in the apical granular region of pancreatic acinar cells

2000 • 353 citations

CaT1 manifests the pore properties of the calcium-release-activated calcium channel

2001 • 350 citations

Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6

2003 • 332 citations

Distribution of transcellular calcium and sodium transport pathways along mouse distal nephron

2001 • 329 citations

Trp12, a novel Trp related protein from kidney

2000 • 303 citations

Expression of CaT-like, a Novel Calcium-selective Channel, Correlates with the Malignancy of Prostate Cancer

2001 • 280 citations

Separation and Characterization of Currents through Store-operated CRAC Channels and Mg²⁺-inhibited Cation (MIC) Channels

2002 • 262 citations

Calcitriol Controls the Epithelial Calcium Channel in Kidney

2001 • 257 citations

Identification and characterization of a novel human vanilloid receptor-like protein, VRL-2

2001 • 252 citations

Calcium-Selective Ion Channel, CaT1, Is Apically Localized in Gastrointestinal Tract Epithelia and Is Aberrantly Expressed in Human Malignancies

2002 • 242 citations

Modulation of renal Ca²⁺transport protein genes by dietary Ca²⁺and 1,25‐dihydroxyvitamin D₃in 25hydroxyvitamin D₃‐1α‐hydroxylase knockout mice

2002 • 241 citations

Inositol Trisphosphate and Cyclic ADP-Ribose–Mediated Release of Ca2+ from Single Isolated Pancreatic Zymogen Granules

1996 • 238 citations

CaT1 and the Calcium Release-activated Calcium Channel Manifest Distinct Pore Properties

2001 • 236 citations

Function and expression of the epithelial Ca2+ channel family: comparison of mammalian ECaC1 and 2

2001 • 234 citations

Localization of the Epithelial Ca2+ Channel in Rabbit Kidney and Intestine

2000 • 218 citations

Human Calcium Transport Protein CaT1

2000 • 209 citations

Localization of the type 3 inositol 1,4,5-trisphosphate receptor in the Ca2+ wave trigger zone of pancreatic acinar cells.

1994 • 205 citations

Vitamin D Receptor (VDR) Knockout Mice Reveal VDR-Independent Regulation of Intestinal Calcium Absorption and ECaC2 and Calbindin D9k mRNA

2003 • 195 citations

Evidence That Zymogen Granules Are Not a Physiologically Relevant Calcium Pool

1997 • 183 citations

Dissociation of the store‐operated calcium current I_CRAC and the Mg‐nucleotide‐regulated metal ion current MagNuM

2002 • 180 citations

Identification of an Aspartic Residue in the P-loop of the Vanilloid Receptor That Modulates Pore Properties

2000 • 180 citations

Distinct Properties of CRAC and MIC Channels in RBL Cells

2002 • 179 citations

CaT1 Expression Correlates with Tumor Grade in Prostate Cancer

2001 • 177 citations

The Single Pore Residue Asp542 Determines Ca2+ Permeation and Mg2+ Block of the Epithelial Ca2+ Channel

2001 • 172 citations

Competitive regulation of CaT-like-mediated Ca ²⁺ entry by protein kinase C and calmodulin

2001 • 165 citations

Vitamin D and Intestinal Calcium Transport: Facts, Speculations and Hypotheses

1995 • 165 citations

A Rat Kidney-specific Calcium Transporter in the Distal Nephron

2000 • 158 citations

Mg2+-dependent Gating and Strong Inward Rectification of the Cation Channel TRPV6

2003 • 155 citations

Whole‐cell and single channel monovalent cation currents through the novel rabbit epithelial Ca²⁺ channel ECaC

2000 • 155 citations

Single-Channel Recording of a Store-Operated Ca ²⁺ Channel in Jurkat T Lymphocytes

1999 • 139 citations

Gene Structure and Regulation of the Murine Epithelial Calcium Channels ECaC1 and 2

2001 • 130 citations

Store depletion and store‐operated Ca²⁺ current in human prostate cancer LNCaP cells: involvement in apoptosis

2000 • 119 citations

Pharmacological modulation of monovalent cation currents through the epithelial Ca²⁺ channel ECaC1

2001 • 116 citations

Vitamin D-inducible calcium transport and gene expression in three Caco-2 cell lines

2002 • 112 citations

Structural Conservation of the Genes Encoding CaT1, CaT2, and Related Cation Channels

2001 • 105 citations

Epithelial calcium transporter expression in human duodenum

2001 • 101 citations

Fast and Slow Inactivation Kinetics of the Ca2+Channels ECaC1 and ECaC2 (TRPV5 and TRPV6)

2002 • 100 citations

Store Depletion-activated CaT1 Currents in Rat Basophilic Leukemia Mast Cells Are Inhibited by 2-Aminoethoxydiphenyl Borate

2002 • 84 citations

CaT1 Contributes to the Stores-operated Calcium Current in Jurkat T-lymphocytes

2002 • 80 citations

Monovalent cation permeability and Ca2+ block of the store-operated Ca2+ current I CRAC in rat basophilic leukemia cells

2002 • 79 citations

Store-operated Ca2+ Current in Prostate Cancer Epithelial Cells

2003 • 64 citations

Calcium uptake and calcium transporter expression by trophoblast cells from human term placenta

2002 • 64 citations

Expression of Calcium Channels along the Differentiation of Cultured Trophoblast Cells from Human Term Placenta1

2002 • 62 citations

Polarized Expression of G Protein-coupled Receptors and an All-or-None Discharge of Ca2+ Pools at Initiation Sites of [Ca2+] Waves in Polarized Exocrine Cells

2001 • 60 citations

Sorting out MIC, TRP, and CRAC Ion Channels

2002 • 59 citations

Molecular Aspects of the Calbindins

1992 • 55 citations

The Recombinant Human TRPV6 Channel Functions as Ca2+Sensor in Human Embryonic Kidney and Rat Basophilic Leukemia Cells

2002 • 53 citations

Hot and Cold TRP Ion Channels

2002 • 45 citations

Permeation through store-operated CRAC channels in divalent-free solution: potential problems and implications for putative CRAC channel genes

2002 • 42 citations

Expression of the Novel Epithelial Ca²⁺Channel ECaC1 in Rat Pancreatic Islets

2002 • 32 citations

Electrophysiologic Characteristics of the Ca-Permeable Channels, ECaC and CaT, in the Kidney

2000 • 32 citations

Single-Channel Activities of the Human Epithelial Ca 2+ Transport Proteins CaT1 and CaT2

2001 • 25 citations

Role of aspartate residues in Ca²⁺affinity and permeation of the distal ECaC1

2002 • 22 citations

A Single Amino Acid Mutation Results in a Rapid Inactivation of Epithelial Calcium Channels

2002 • 12 citations