Evidence That Zymogen Granules Are Not a Physiologically Relevant Calcium Pool

Type I, II, and III Inositol 1,4,5-Trisphosphate Receptors Are Unequally Susceptible to Down-regulation and Are Expressed in Markedly Different Proportions in Different Cell Types

1995 • 418 citations

Cytosolic Ca2+ gradients triggering unidirectional fluid secretion from exocrine pancreas

1990 • 393 citations

ATP-dependent accumulation and inositol trisphosphate- or cyclic ADP-ribose-mediated release of Ca2+ from the nuclear envelope

1995 • 364 citations

Subcellular distribution of Ca2+ release channels underlying Ca2+ waves and oscillations in exocrine pancreas

1993 • 357 citations

Effect of inositol-1,4,5-trisphosphate on isolated subcellular fractions of rat pancreas

1984 • 305 citations

Inositol Trisphosphate and Cyclic ADP-Ribose–Mediated Release of Ca2+ from Single Isolated Pancreatic Zymogen Granules

1996 • 238 citations

Localization of the type 3 inositol 1,4,5-trisphosphate receptor in the Ca2+ wave trigger zone of pancreatic acinar cells.

1994 • 205 citations

Mechanism of Ca2+ wave propagation in pancreatic acinar cells.

1992 • 159 citations

A procedure for the rapid preparation of mitochondria from rat liver

1982 • 106 citations

Localization of inositol trisphosphate receptor subtype 3 to insulin and somatostatin secretory granules and regulation of expression in islets and insulinoma cells.

1994 • 88 citations

Tyrosine Kinase Inhibitors Attenuate "Capacitative" Ca2+ Influx in Rat Pancreatic Acinar Cells

1994 • 71 citations

Identification and cloning of GP-3 from rat pancreatic acinar zymogen granules as a glycosylated membrane-associated lipase

1993 • 71 citations

Degradation of Inositol 1,4,5-Trisphosphate Receptors during Cell Stimulation Is a Specific Process Mediated by Cysteine Protease Activity

1996 • 57 citations

Sphingosine metabolism induces Ca2+ oscillations in rat pancreatic acinar cells

1993 • 57 citations

Rapid isolation of pancreatic islets from collagenase digested pancreas by sedimentation through percoll™ at unit gravity

1977 • 51 citations

ATP sensitive K+ conductance in pancreatic zymogen granules: Block by glyburide and activation by diazoxide

1992 • 48 citations

GP-3, a newly characterized glycoprotein on the inner surface of the zymogen granule membrane, undergoes regulated secretion.

1994 • 44 citations

Inositol 1,4,5-trisphosphate receptor subtype 3 in pancreatic islet cell secretory granules revisited.

1996 • 42 citations

Protein kinase activity associated with pancreatic zymogen granules

1985 • 37 citations

A rapid method for the preparation of sarcolemmal vesicles from rat aorta, and the stimulation of calcium uptake into the vesicles by cyclic AMP‐dependent protein kinase

1980 • 19 citations

Potassium- and ionophore A23187-induced discharge of secretory protein in guinea pig pancreatic lobules. Role of extracellular calcium.

1980 • 19 citations

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