Insulin-like growth factors in human breast cancer

Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase

1995 • 1,973 citations

Induction of the growth inhibitor IGF-binding protein 3 by p53

1995 • 884 citations

c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

1994 • 747 citations

CDK-Independent Activation of Estrogen Receptor by Cyclin D1

1997 • 698 citations

Insulin-like growth factor binding proteins and their role in controlling IGF actions

1997 • 510 citations

A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis

1994 • 391 citations

Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells.

1990 • 385 citations

Insulin-like growth factor II stimulates cell proliferation through the insulin receptor

1997 • 234 citations

Mammary cancer in transgenic mice expressing insulin-like growth factor II (IGF-II)

1995 • 190 citations

Activation of estrogen receptor-mediated gene transcription by IGF-I in human breast cancer cells

1997 • 183 citations

Overexpressed IGF-I Receptors Reduce Estrogen Growth Requirements, Enhance Survival, and Promote E-Cadherin-Mediated Cell–Cell Adhesion in Human Breast Cancer Cells

1997 • 136 citations

The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R), a putative breast tumor suppressor gene

1998 • 125 citations

A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity.

1992 • 118 citations

Intact and amino-terminally shortened forms of insulin-like growth factor I induce mammary gland differentiation and development.

1992 • 114 citations

Prostate specific antigen in breast cancer, benign breast disease and normal breast tissue

1996 • 109 citations

Igf-independent regulation of breast cancer growth by IGF binding proteins

1998 • 105 citations

The prognostic value of insulin-like growth factor-I in breast cancer patients. Results of a follow-up study on 126 patients

1994 • 105 citations

Paracrine/autocrine regulation of breast cancer by the insulin-like growth factors

1998 • 101 citations

The localization of the insulin-like growth factor receptor 1 (IGFR-1) in benign and malignant breast tissue

1997 • 100 citations

Insulin-like growth factor mediated stromal-epithelial interactions in human breast cancer

1994 • 98 citations

Correlation of Insulin-Like Growth Factor-Binding Protein-3 Messenger RNA With Protein Expression in Primary Breast Cancer Tissues: Detection of Higher Levels in Tumors With Poor Prognostic Features

1996 • 96 citations

Type I insulin-like growth factor receptor gene expression in normal human breast tissue treated with oestrogen and progesterone

1997 • 94 citations

Role of IGF-I in normal mammary development

1998 • 93 citations

Type I insulin-like growth factor receptor function in breast cancer

1998 • 92 citations

Associations between insulin-like growth factors and their binding proteins and other prognostic indicators in breast cancer

1996 • 84 citations

Effect of growth factors on estrogen receptor mediated gene expression

1996 • 78 citations

Insulin-like Growth Factor Binding Protein 3 (IGF-BP3) Inhibits Estrogen-Stimulated Breast Cancer Cell Proliferation

1994 • 71 citations

Igf system components as prognostic markers in breast cancer

1998 • 68 citations

IGF-II mRNA and protein are expressed in the stroma of invasive breast cancers: Anin situ hybridization and immunohistochemistry study

1996 • 62 citations

Hybrid and Atypical Insulin/lnsulin-Like Growth Factor I Receptors

1994 • 57 citations

The insulin‐like growth factor I receptor gene is the target for the 15q26 amplicon in breast cancer

1994 • 56 citations

Estradiol enhances the stimulatory effect of insulin-like growth factor- I (IGF-I) on mammary development and growth hormone-induced IGF-I messenger ribonucleic acid

1995 • 51 citations

Insulin-like growth factor 1 receptors (IGF1-R) and IGF1 in human breast tumors

1990 • 48 citations

Comparison between novel steroid‐like and conventional nonsteroidal antioestrogens in inhibiting oestradiol‐ and IGF‐I‐induced proliferation of human breast cancer‐derived cells

1995 • 43 citations

The insulin-like growth factors and breast cancer — revisited

1998 • 34 citations

Insulin/IGF-1 modulation of the expression of two estrogen-induced genes in MCF-7 cells

1996 • 28 citations

Insulin-like growth factor-I induces cyclin-D1 expression in MG63 human osteosarcoma cells in vitro

1994 • 28 citations

Cyclins and breast cancer

1996 • 21 citations

Affinity for the insulin-like growth factor-II (IGF-II) receptor inhibits autocrine IGF-II activity in MCF-7 breast cancer cells

1996 • 19 citations

Decreased Phosphorylation of Mutant Insulin Receptor by Protein Kinase C and Protein Kinase A

1995 • 17 citations

Regulation of insulin-like growth factor (IGF)-binding protein-6 and mannose 6-phosphate/IGF-II receptor expression in IGF-IL-overexpressing NIH 3T3 cells

1995 • 14 citations