Sequence of the Notch Locus of Drosophila melanogaster: Relationship of the Encoded Protein to Mammalian Clotting and Growth Factors

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing

1984 • 4,231 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs

1984 • 3,334 citations

Construction of improved M13 vectors using oligodeoxynucleotide-directed mutagenesis

1983 • 2,609 citations

Buffer gradient gels and 35S label as an aid to rapid DNA sequence determination.

1983 • 2,456 citations

Molecular drive: a cohesive mode of species evolution

1982 • 1,579 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

pEMBL: a new family of single stranded plasmids

1983 • 1,231 citations

Nucleotide sequence from the neurogenic locus Notch implies a gene product that shares homology with proteins containing EGF-like repeats

1985 • 1,063 citations

Mechanisms for the incorporation of proteins in membranes and organelles.

1982 • 875 citations

Similar Amino Acid Sequences: Chance or Common Ancestry?

1981 • 855 citations

The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins

1985 • 845 citations

An interactive graphics program for comparing and aligning nucleic acid and amino acid sequences

1982 • 801 citations

The engrailed locus of drosophila: Structural analysis of an embryonic transcript

1985 • 735 citations

A mew computer method for the storage and manipulation of DNA gel reading data

1980 • 679 citations

Mouse prepro-epidermal growth factor synthesis by the kidney and other tissues

1985 • 568 citations

Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursor

1983 • 520 citations

On the phenotype and development of mutants of early neurogenesis inDrosophila melanogaster

1983 • 493 citations

Evolution of the proteases of blood coagulation and fibrinolysis by assembly from modules

1985 • 492 citations

Structure of a Mouse Submaxillary Messenger RNA Encoding Epidermal Growth Factor and Seven Related Proteins

1983 • 448 citations

opa: A novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster

1985 • 404 citations

Cloning and sequence analysis of a cDNA for rat transforming growth factor-α

1985 • 388 citations

Domain map of the LDL receptor: Sequence homology with the epidermal growth factor precursor

1984 • 377 citations

Early neurogenesis in wild-typeDrosophila melanogaster

1984 • 372 citations

lin-12, a nematode homeotic gene, is homologous to a set of mammalian proteins that includes epidermal growth factor

1985 • 369 citations

Graphic methods to determine the function of nucleic acid sequences

1984 • 367 citations

The gene structure of human anti-haemophilic factor IX.

1984 • 361 citations

The Primary Structure of High Molecular Mass Urokinase from Human Urine. The Complete Amino Arid Sequence of the A Chain

1982 • 312 citations

The structure of the human tissue-type plasminogen activator gene: correlation of intron and exon structures to functional and structural domains.

1984 • 303 citations

Amino acid sequence of the heavy chain of human alpha-factor XIIa (activated Hageman factor).

1985 • 232 citations

Homeo box genes of the Antennapedia and Bithorax Complexes of Drosophila

1985 • 219 citations

Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster.

1983 • 213 citations

Computer-based characterization of epidermal growth factor precursor

1984 • 212 citations

The Notch locus of Drosophila melanogaster

1983 • 203 citations

The Drosophila EGF receptor gene homolog: Conservation of both hormone binding and kinase domains

1985 • 202 citations

Vaccinia virus 19-kilodalton protein: relationship to several mammalian proteins, including two growth factors.

1984 • 201 citations

Cassette of Eight Exons Shared by Genes for LDL Receptor and EGF Precursor

1985 • 185 citations

The sequence and topology of human complement component C9.

1985 • 179 citations

Complete Nucleotide Sequences of Two Adjacent Early Vaccinia Virus Genes Located Within the Inverted Terminal Repetition

1982 • 133 citations

Characterization of an almost full-length cDNA coding for human blood coagulation factor X.

1985 • 126 citations

An efficient method for finding repeats in molecular sequences

1983 • 116 citations

THE PRIMARY STRUCTURE OF HUMAN UROGASTRONE

1977 • 99 citations

Cloning and sequencing of liver cDNA coding for bovine protein C.

1984 • 95 citations

ALLELIC NEGATIVE COMPLEMENTATION AT THE ABRUPTEX LOCUS OF DROSOPHILA MELANOGASTER

1975 • 88 citations

Amino acid sequence of bovine protein Z: a vitamin K‐dependent serine protease homolog

1985 • 83 citations

Epidermal growth factor: Is the precursor a receptor?

1985 • 81 citations

NEGATIVE COMPLEMENTATION AT THE NOTCH LOCUS OF DROSOPHILA MELANOGASTER

1975 • 79 citations

A Drosophila genomic sequence with homology to human epidermal growth factor receptor

1985 • 66 citations

GENETIC BASIS FOR TWO TYPES OF RECESSIVE LETHALITY AT THE NOTCH LOCUS OF DROSOPHILA

1971 • 54 citations

INTRAGENIC DELETIONS AND SALIVARY BAND RELATIONSHIPS IN DROSOPHILA

1975 • 40 citations

Identification of a novel receptor in Drosophila for both epidermal growth factor and insulin.

1985 • 27 citations

On the cell lethality of Notch and Abruptex mutations of Drosophila melanogaster

2009 • 13 citations

SUPPRESSION OF THE FACET-STRAWBERRY POSITION EFFECT IN DROSOPHILA BY LESIONS ADJACENT TO NOTCH

1985 • 12 citations