The α1D-adrenergic receptor directly regulates arterial blood pressure via vasoconstriction

LIGAND: A versatile computerized approach for characterization of ligand-binding systems

1980 • 8,534 citations

A Noninvasive Computerized Tail-Cuff System for Measuring Blood Pressure in Mice

1995 • 585 citations

Molecular cloning and expression of the cDNA for the hamster alpha 1-adrenergic receptor.

1988 • 566 citations

α1Adrenoceptor subtypes linked to different mechanisms for increasing intracellular Ca2+ in smooth muscle

1987 • 482 citations

Molecular cloning and expression of the cDNA for a novel alpha 1-adrenergic receptor subtype.

1990 • 417 citations

Evidence for more than one type of post-junctional α-Adrenoceptor

1982 • 399 citations

Glyceraldehyde-3-phosphate dehydrogenase mRNA is a major interleukin 2-induced transcript in a cloned T-helper lymphocyte

1990 • 391 citations

Transthoracic Echocardiography in Models of Cardiac Disease in the Mouse

1996 • 372 citations

Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy.

1994 • 369 citations

Targeted Disruption of the β2 Adrenergic Receptor Gene

1999 • 325 citations

Subtype Specific Regulation of Human Vascular α ₁ -Adrenergic Receptors by Vessel Bed and Age

1999 • 291 citations

Decreased blood pressure response in mice deficient of the α _1b -adrenergic receptor

1997 • 282 citations

A Novel Negative Selection for Homologous Recombinants Using Diphtheria Toxin A Fragment Gene

1993 • 232 citations

α1-Adrenergic receptor regulation: basic science and clinical implications

2000 • 220 citations

The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation.

1997 • 209 citations

Use of recombinant α1-adrenoceptors to characterize subtype selectivity of drugs for the treatment of prostatic hypertrophy

1995 • 183 citations

Characterization of an α_1D‐adrenoceptor mediating the contractile response of rat aorta to noradrenaline

1995 • 181 citations

Functional Consequences of Altering Myocardial Adrenergic Receptor Signaling

2000 • 160 citations

Cloning, Functional Expression and Tissue Distribution of Human cDNA for the α1C-Adrenergic Receptor

1993 • 154 citations

Transgenic Mice with Cardiac Overexpression of α1B-Adrenergic Receptors

1997 • 151 citations

Regulation of Vascular Smooth Muscle Growth by α1-Adrenoreceptor Subtypes in Vitro and in Situ

1995 • 124 citations

α1-Adrenoceptor-induced contractility in rat aorta is mediated by the α1D subtype

1996 • 117 citations

G Protein-Coupled Receptors: Functional and Mechanistic Insights Through Altered Gene Expression

1998 • 106 citations

Hypotension, Autonomic Failure, and Cardiac Hypertrophy in Transgenic Mice Overexpressing the α1B-Adrenergic Receptor

2001 • 97 citations

α1-Adrenoceptors mediating contraction in arteries of normotensive and spontaneously hypertensive rats are of the α1D or α1A subtypes

1996 • 88 citations

Characterization of α_1D‐adrenoceptor subtype in rat myocardium, aorta and other tissues

1996 • 79 citations

Functional evidence of α_1D‐adrenoceptors in the vasculature of young and adult spontaneously hypertensive rats

1999 • 67 citations

Insertion/Deletion Polymorphism of the Angiotensin I-Converting Enzyme Gene Is Not Associated With Restenosis After Coronary Stent Placement

2000 • 65 citations

Recent advances in the molecular pharmacology of the α1-adrenergic receptors

1996 • 56 citations

Systolic Blood Pressure in Eight Inbred Strains of Mice

1966 • 42 citations

A single nucleotide change in the prolidase gene in fibroblasts from two patients with polypeptide positive prolidase deficiency. Expression of the mutant enzyme in NIH 3T3 cells.

1990 • 41 citations

Evidence for an age-dependent functional expression of α1D-adrenoceptors in the rat vasculature

1997 • 40 citations

Molecular Cloning of α_1d‐Adrenergic Receptor and Tissue Distribution of Three α₁‐Adrenergic Receptor Subtypes in Mouse

1995 • 39 citations

Differential response to chloroethylclonidine in blood vessels of normotensive and spontaneously hypertensive rats: role of α_1D‐ and α_1A‐adrenoceptors in contraction

2000 • 35 citations

Platelet-Derived Growth Factor Inhibits α1D-Adrenergic Receptor Expression in Vascular Smooth Muscle Cells In Vitro and Ex Vivo

1999 • 12 citations

Characterization of the Mouse .ALPHA.1D-Adrenergic Receptor Gene.

1999 • 8 citations

Effects of the antihypertensive agent, cicletanine, on noradrenaline release and vasoconstriction in perfused mesenteric artery of SHR

1998 • 4 citations