Differential response to chloroethylclonidine in blood vessels of normotensive and spontaneously hypertensive rats: role of α_1D‐ and α_1A‐adrenoceptors in contraction

The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

1980 • 12,033 citations

Pharmacological subclassification of α₁‐adrenoceptors in vascular smooth muscle

1990 • 308 citations

BMY 7378 is a selective antagonist of the D subtype of α1-adrenoceptors

1995 • 296 citations

Comparison of alpha 1-adrenergic receptor subtypes distinguished by chlorethylclonidine and WB 4101.

1988 • 268 citations

Heterogeneity of alpha 1-adrenergic receptors revealed by chlorethylclonidine.

1987 • 267 citations

Constitutive activation of a single effector pathway: evidence for multiple activation states of a G protein-coupled receptor.

1996 • 188 citations

The specific contribution of the novel alpha-1D adrenoceptor to the contraction of vascular smooth muscle.

1995 • 181 citations

Characterization of an α_1D‐adrenoceptor mediating the contractile response of rat aorta to noradrenaline

1995 • 181 citations

Subtypes of α1adrenoceptors in rat blood vessels

1990 • 141 citations

Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes.

1994 • 123 citations

Cloning, expression, and tissue distribution of the rat homolog of the bovine alpha 1C-adrenergic receptor provide evidence for its classification as the alpha 1A subtype.

1994 • 116 citations

Subtype-Specific Differences in Subcellular Localization of α₁-Adrenoceptors: Chlorethylclonidine Preferentially Alkylates the Accessible Cell Surface α₁-Adrenoceptors Irrespective of the Subtype

1997 • 106 citations

Identification of the mRNA for the novel alpha 1D-adrenoceptor and two other alpha 1-adrenoceptors in vascular smooth muscle.

1994 • 89 citations

α1-Adrenoceptors mediating contraction in arteries of normotensive and spontaneously hypertensive rats are of the α1D or α1A subtypes

1996 • 88 citations

Immunocytochemical localization of the alpha-1B adrenergic receptor and the contribution of this and the other subtypes to vascular smooth muscle contraction: analysis with selective ligands and antisense oligonucleotides.

1997 • 87 citations

Pharmacological characterization of an α_1A‐adrenoceptor mediating contractile responses to noradrenaline in isolated caudal artery of rat

1997 • 82 citations

?1 Adrenoceptor subtypes: A synopsis of their pharmacology and molecular biology

1996 • 70 citations

Heterogeneity of Postjunctional α<sub>1</sub>-Adrenoceptors in Mammalian Aortae: Subclassification Based on Chlorethylclonidine, WB 4101 and Nifedipine

1992 • 62 citations

Subtypes of .ALPHA.1-Adrenoceptors Involved in Noradrenaline-Induced Contractions of Rat Thoracic Aorta and Dog Carotid Artery.

1991 • 58 citations

STUDIES ON SOME para‐SUBSTITUTED CLONIDINE DERIVATIVES THAT EXHIBIT AN α‐ADRENOCEPTOR STIMULANT ACTIVITY

1980 • 57 citations

Synthesis and Biological Profile of the Enantiomers of [4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)-cis-octahydroquinoxalin-1-yl]furan- 2-ylmethanone (Cyclazosin), a Potent Competitive α_1B-Adrenoceptor Antagonist

1996 • 55 citations

Selective irreversible binding of chloroethylclonidine at alpha 1- and alpha 2-adrenoceptor subtypes.

1993 • 51 citations

Species differences in chlorethylclonidine antagonism at vascular alpha-1 adrenergic receptors.

1990 • 47 citations

Receptor interactions of imidazolines. IV. Structural requirements for alpha adrenergic receptor occupation and receptor activation by clonidine and a series of structural analogs in rat aorta.

1980 • 41 citations

Selectivity of the imidazoline α‐adrenoceptor agonists (oxymetazoline and cirazoline) for human cloned α₁‐adrenoceptor subtypes

1995 • 40 citations

Adrenoceptors in SHR: Alterations in binding characteristics and intracellular signal transduction pathways

1995 • 37 citations

Chloroethylclonidine: an irreversible agonist at prejunctional α₂‐adrenoceptors in rat vas deferens

1993 • 34 citations

The α-adrenoceptor-mediated actions of chloroethylclonidine

1997 • 27 citations

?-Adrenoceptor subtypes in rat aorta and mesenteric small arteries are preserved during left ventricular dysfunction post-myocardial infarction

1997 • 26 citations

Guanine nucleotide-binding proteins in aortic smooth muscle from hypertensive rats.

1994 • 26 citations

Alteration of α1-adrenoceptor subtypes in aortas of 12-month-old spontaneously hypertensive rats

1998 • 25 citations

Chloroethylclonidine irreversibly activates postjunctional alpha2-adrenoceptors in the dog saphenous vein

1993 • 24 citations

Investigation of the actions of chloroethylclonidine in rat aorta

1995 • 23 citations

Increased Responsiveness and Decreased Expression of G Proteins in Deoxycorticosterone Hypertension

1996 • 20 citations

WB4101- and CEC-sensitive positive inotropic actions of phenylephrine in rat cardiac muscle

1994 • 16 citations

Further investigation of the α-adrenoceptor-mediated actions of chloroethylclonidine in rat aorta

1997 • 13 citations

Chloroethylclonidine is a partial α1-adrenoceptor agonist in aorta and caudal arteries of the Wistar Kyoto rat

1998 • 9 citations

Chloroethylclonidine is a partial α1A-adrenoceptor agonist in cells expressing recombinant α1-adrenoceptor subtypes

1997 • 9 citations