Mapping and Mutagenesis of the Amino-Terminal Transcriptional Repression Domain of the Drosophila Krüppel Proteint†

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

PCR protocols — A guide to methods and applications

1990 • 12,897 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Current protocols in molecular biology

1988 • 2,473 citations

Analysis of Sp1 in vivo reveals mutiple transcriptional domains, including a novel glutamine-rich activation motif

1988 • 1,403 citations

The human estrogen receptor has two independent nonacidic transcriptional activation functions

1989 • 1,066 citations

Five intermediate complexes in transcription initiation by RNA polymerase II

1989 • 1,033 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

Transcriptional repression by YY1, a human GLI-Krüippel-related protein, and relief of repression by adenovirus E1A protein

1991 • 1,023 citations

Mitochondrial targeting sequences may form amphiphilic helices.

1986 • 1,019 citations

Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.

1988 • 830 citations

Prediction of Protein Structure and the Principles of Protein Conformation

1989 • 814 citations

Ssn6-Tup1 is a general repressor of transcription in yeast

1992 • 680 citations

Molecular cloning and functional analysis of Drosophila TAF110 reveal properties expected of coactivators

1993 • 589 citations

Steroid hormone receptors compete for factors that mediate their enhancer function

1989 • 580 citations

Mechanism of action of an acidic transcriptional activator in vitro

1991 • 557 citations

Characterization and localization of the even-skipped protein of Drosophila.

1987 • 496 citations

Transcriptional Repression Mediated by the WT1 Wilms Tumor Gene Product

1991 • 492 citations

Transcriptional repression of eukaryotic promoters

1989 • 481 citations

Expression of the Wilms' tumor gene WT1 in the murine urogenital system.

1991 • 447 citations

Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains

1992 • 446 citations

Structural homology of the product of the Drosophila Krüppel gene with Xenopus transcription factor IIIA

1986 • 406 citations

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

1992 • 379 citations

Distinct classes of transcriptional activating domains function by different mechanisms

1990 • 368 citations

Reduced binding of TFIID to transcriptionally compromised mutants of VP16

1991 • 362 citations

Transcriptional regulation of a pair-rule stripe in Drosophila.

1991 • 354 citations

Regulation of a Segmentation Stripe by Overlapping Activators and Repressors in the Drosophila Embryo

1991 • 321 citations

A transferable silencing domain is present in the thyroid hormone receptor, in the v-erbA oncogene product and in the retinoic acid receptor.

1992 • 302 citations

Functional domains of the Drosophila Engrailed protein.

1993 • 280 citations

Early and late periodic patterns of even skipped expression are controlled by distinct regulatory elements that respond to different spatial cues

1989 • 273 citations

Sequence-specific DNA-binding activities of the gap proteins encoded by hunchback and Krüppel in Drosophila

1989 • 270 citations

Active repression of transcription by the engrailed homeodomain protein.

1991 • 248 citations

Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain.

1993 • 241 citations

Drosophila Krüppel protein is a transcriptional represser

1990 • 228 citations

Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targets

1990 • 221 citations

The tramtrack gene encodes a Drosophila finger protein that interacts with the ftz transcriptional regulatory region and shows a novel embryonic expression pattern.

1990 • 218 citations

The Wilms tumour gene WT1 is expressed in murine mesoderm–derived tissues and mutated in a human mesothelioma

1993 • 211 citations

The Wilms' tumor gene product WT1 activates or suppresses transcription through separate functional domains

1993 • 198 citations

Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides

1987 • 183 citations

Concentration-dependent transcriptional activation or repression by Krüppel from a single binding site

1991 • 166 citations

The carboxyl-terminal two-thirds of the ADP/ATP carrier polypeptide contains sufficient information to direct translocation into mitochondria.

1987 • 160 citations

Stringent regulation of stably integrated chloramphenicol acetyl transferase genes by E. coli lac repressor in monkey cells

1988 • 152 citations

The products of the Drosophila gap genes hunchback and Krüppel bind to the hunchback promoters

1989 • 146 citations

Lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells

1987 • 141 citations

Krüppel requirement for knirps enhancement reflects overlapping gap gene activities in the Drosophila embryo

1989 • 140 citations

Three hormone receptor-like Drosophila genes encode an identical DNA-binding finger.

1989 • 127 citations

Making stripes in the Drosophila embryo

1990 • 124 citations

The giant gene of Drosophila encodes a b-ZIP DNA-binding protein that regulates the expression of other segmentation gap genes

1992 • 112 citations

Correlative changes in homoeotic and segmentation gene expression in Krüppel mutant embryos of Drosophila

1986 • 111 citations

Activation and repression of transcription by the gap proteins hunchback and Krüppel in cultured Drosophila cells.

1991 • 107 citations

Dimerization and the control of transcription by Krüppel

1993 • 106 citations

A novel spatial transcription pattern associated with the segmentation gene, giant, of Drosophila.

1989 • 96 citations

Differential regulation of transcription preinitiation complex assembly by activator and repressor homeo domain proteins.

1992 • 78 citations

Fused Protein Domains Inhibit DNA Binding by LexA

1992 • 76 citations

Analysis of maternal effect mutant combinations elucidates regulation and function of the overlap of hunchback and Krüppel gene expression in the Drosophila blastoderm embryo

1989 • 68 citations

Selective repression of transcriptional activators at a distance by the Drosophila Krüppel protein.

1993 • 46 citations

How to fill a gap in the Drosophila embryo

1987 • 24 citations

NGFIA (EGR1) Contains Transcription Activating Domains in Both the Amino Terminal and Carboxyl Terminal Regions of the Protein

1993 • 8 citations