GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor–stimulated muscle glucose utilization

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

2002 • 2,024 citations

A Muscle-Specific Insulin Receptor Knockout Exhibits Features of the Metabolic Syndrome of NIDDM without Altering Glucose Tolerance

1998 • 1,173 citations

Exercise, Glucose Transport, and Insulin Sensitivity

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A Role for AMP-Activated Protein Kinase in Contraction- and Hypoxia-Regulated Glucose Transport in Skeletal Muscle

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Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance

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1999 • 719 citations

Acute stimulation of glucose metabolism in mice by leptin treatment

1997 • 717 citations

The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members

2001 • 692 citations

Metabolic stress and altered glucose transport: activation of AMP-activated protein kinase as a unifying coupling mechanism.

2000 • 463 citations

Exercise Induces Isoform-Specific Increase in 5′AMP-Activated Protein Kinase Activity in Human Skeletal Muscle

2000 • 350 citations

AFFERENT IMPULSE DISCHARGES FROM GLUCORECEPTORS IN THE LIVER OF THE GUINEA PIG

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Microinjection of leptin into the ventromedial hypothalamus increases glucose uptake in peripheral tissues in rats.

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Participation of Hepatic Glucoreceptors in the Control of Intake of Food

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Glucose Competence of the Hepatoportal Vein Sensor Requires the Presence of an Activated Glucagon-Like Peptide-1 Receptor

2001 • 247 citations

GLUTX1, a Novel Mammalian Glucose Transporter Expressed in the Central Nervous System and Insulin-sensitive Tissues

2000 • 230 citations

Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2-null mice.

2000 • 200 citations

Glucose toxicity and the development of diabetes in mice with muscle-specific inactivation of GLUT4

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Transgenic Reexpression of GLUT1 or GLUT2 in Pancreatic β Cells Rescues GLUT2-null Mice from Early Death and Restores Normal Glucose-stimulated Insulin Secretion

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Demonstration of the influence of an hepatic glucosensitive mechanism on food-intake

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Functional correlations between lateral hypothalamic glucose-sensitive neurons and hepatic portal glucose-sensitive units in rat

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Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal glucose sensor stimulates glucose utilization.

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AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge

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In Vivo Administration of Leptin Activates Signal Transduction Directly in Insulin-Sensitive Tissues: Overlapping but Distinct Pathways from Insulin

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Diverse effects of Glut 4 ablation on glucose uptake and glycogen synthesis in red and white skeletal muscle.

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Moving GLUT4: the biogenesis and trafficking of GLUT4 storage vesicles

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Lilly lecture 1995. Glucose transport: pivotal step in insulin action

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Regulatory mechanism of the ventromedial hypothalamus in enhancing glucose uptake in skeletal muscles

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Sensing by intrahepatic muscarinic nerves of a portal‐arterial glucose concentration gradient as a signal for insulin‐dependent glucose uptake in the perfused rat liver

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Reflex control of the autonomic nervous system activity from the glucose sensors in the liver in normal and midpontine-transected animals

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The role of liver glucosensors in the integrated sympathetic response induced by deep hypoglycemia in dogs

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The nerves, the liver, and the route of feeding: An integrated response to nutrient delivery

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Differential effects of insulin and exercise on Rab4 distribution in rat skeletal muscle

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