Effects of Intron Length on Differential Processing of Mouse μ Heavy-Chain mRNA

A New Mouse Myeloma Cell Line that Has Lost Immunoglobulin Expression but Permits the Construction of Antibody-Secreting Hybrid Cell Lines

1979 • 1,885 citations

SPLICING OF MESSENGER RNA PRECURSORS

1986 • 1,233 citations

Nucleotide sequence of bacteriophage λ DNA

1982 • 1,171 citations

Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways

1980 • 880 citations

Expression of a Bacterial Gene in Mammalian Cells

1980 • 788 citations

Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain

1980 • 659 citations

Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends

1980 • 562 citations

Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

1985 • 524 citations

A multicomponent complex is involved in the splicing of messenger RNA precursors

1985 • 451 citations

A minimal intron length but no specific internal sequence is required for splicing the large rabbit β-globin intron

1984 • 328 citations

Alternative splicing caused by RNA secondary structure

1985 • 274 citations

Requirement of a downstream sequence for generation of a poly(A) addition site

1984 • 261 citations

A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation

1984 • 251 citations

The molecular biology of immunoglobulin D

1984 • 152 citations

Molecular basis of a mouse strain-specific anti-hapten response

1983 • 150 citations

A sequence downstream of A-A-U-A-A-A is required for formation of simian virus 40 late mRNA 3' termini in frog oocytes.

1985 • 139 citations

Regulated production of mu m and mu s mRNA requires linkage of the poly(A) addition sites and is dependent on the length of the mu s-mu m intron.

1986 • 109 citations

Unusual sequences in the murine immunoglobulin μ–δ heavy-chain region

1983 • 108 citations

Nonconsensus branch-site sequences in the in vitro splicing of transcripts of mutant rabbit beta-globin genes.

1985 • 96 citations

Role of an RNA cleavage/poly(A) addition site in the production of membrane-bound and secreted IgM mRNA.

1985 • 93 citations

Establishment of B cell hybridomas with B cell surface antigens.

1982 • 80 citations

Structure of two unlinked Drosophila melanogaster glyceraldehyde-3-phosphate dehydrogenase genes.

1985 • 67 citations

Mutations downstream of the polyadenylation site of a Xenopus β-globin mRNA affect the position but not the efficiency of 3′ processing

1986 • 63 citations

Identification of a Sequence Element on the 3′ Side of AAUAAA Which Is Necessary for Simian Virus 40 Late mRNA 3′-End Processing

1985 • 59 citations

Identification of Sequences in the Herpes Simplex Virus Thymidine Kinase Gene Required for Efficient Processing and Polyadenylation

1985 • 41 citations

Fine Mapping of an Immunoglobulin Gene Activator

1984 • 24 citations