Regulated production of mu m and mu s mRNA requires linkage of the poly(A) addition sites and is dependent on the length of the mu s-mu m intron.

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways

1980 • 880 citations

The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3′ termini

1985 • 652 citations

Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes

1983 • 627 citations

Cell-type specificity of iminunoglobulin gene expression is regulated by at least three DNA sequence elements

1985 • 588 citations

Synthesis of secreted and membrane-bound immunoglobulin mu heavy chains is directed by mRNAs that differ at their 3′ ends

1980 • 562 citations

Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

1985 • 524 citations

Organization and reorganization of immunoglobulin genes in A-MuLV-transformed cells: Rearrangement of heavy but not light chain genes

1981 • 497 citations

A multicomponent complex is involved in the splicing of messenger RNA precursors

1985 • 451 citations

The "Spliceosome": Yeast Pre-Messenger RNA Associates with a 40 S Complex in a Splicing-Dependent Reaction

1985 • 421 citations

Intron sequences involved in lariat formation during pre-mRNA splicing

1985 • 402 citations

Murine B Cell Leukemia Line with Inducible Surface Immunoglobulin Expression

1978 • 388 citations

A minimal intron length but no specific internal sequence is required for splicing the large rabbit β-globin intron

1984 • 328 citations

The synthesis and processing of the messenger RNAs specifying heavy and light chain immunoglobulins in MPC-11 cells

1978 • 324 citations

Requirement of a downstream sequence for generation of a poly(A) addition site

1984 • 261 citations

A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation

1984 • 251 citations

Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit β-globin gene

1983 • 235 citations

Multiple Immunoglobulin Heavy-Chain Gene Transcripts in Abelson Murine Leukemia Virus-Transformed Lymphoid Cell Lines

1982 • 228 citations

Mapping of Heavy Chain Genes for Mouse Immunoglobulins M and D

1980 • 188 citations

Role of the 3′ splice site consensus sequence in mammalian pre-mRNA splicing

1985 • 184 citations

Characterization of the multigene family encoding the mouse S16 ribosomal protein: strategy for distinguishing an expressed gene from its processed pseudogene counterparts by an analysis of total genomic DNA.

1985 • 179 citations

Characterization of productive and sterile transcripts from the immunoglobulin heavy-chain locus: processing of micron and muS mRNA.

1983 • 165 citations

Immunoglobulin messenger RNAs in murine cell lines that have characteristics of immature B lymphocytes

1979 • 158 citations

The molecular biology of immunoglobulin D

1984 • 152 citations

Mode of regulation of immunoglobulin μ- and δ-chain expression varies during B-lymphocyte maturation

1984 • 146 citations

Transcriptional regulation of the mu-delta heavy chain locus in normal murine B lymphocytes.

1984 • 112 citations

Unusual sequences in the murine immunoglobulin μ–δ heavy-chain region

1983 • 108 citations

During B-cell differentiation enhancer activity and transcription rate of immunoglobulin heavy chain genes are high before mRNA accumulation

1986 • 105 citations

Transcriptional and posttranscriptional control of immunoglobulin mRNA production during Blymphocyte development

1986 • 99 citations

Role of an RNA cleavage/poly(A) addition site in the production of membrane-bound and secreted IgM mRNA.

1985 • 93 citations

Characterization of Productive and Sterile Transcripts from the Immunoglobulin Heavy-Chain Locus: Processing of μ_m and μ_s mRNA

1983 • 63 citations

The sequence of the human immunoglobulin μ-δ intron reveals possible vestigial switch segments

1984 • 60 citations

Characterization of the Multigene Family Encoding the Mouse S16 Ribosomal Protein: Strategy for Distinguishing an Expressed Gene from Its Processed Pseudogene Counterparts by an Analysis of Total Genomic DNA

1985 • 59 citations

Tandem kappa immunoglobulin promoters are equally active in the presence of the kappa enhancer: Implications for models of enhancer function

1986 • 47 citations

Cell-specific expression of secreted versus membrane forms of immunoglobulin gamma 2b mRNA involves selective use of alternate polyadenylation sites.

1985 • 46 citations

Sequences near the 3′ Secretion-Specific Polyadenylation Site Influence Levels of Secretion-Specific and Membrane-Specific IgG2b mRNA in Myeloma Cells

1986 • 42 citations

Synthesis of two mRNAs by utilization of alternate polyadenylation sites: expression of SV40-mouse immunoglobulin mu chain gene recombinants in Cos monkey cells.

1984 • 42 citations

The 5′-terminal sequences of immunoglobulin messenger RNAs of a mouse myeloma

1978 • 28 citations

Cell-Type-Specific Synthesis of Murine Immunoglobulin μ RNA from an Adenovirus Vector

1986 • 28 citations

Cell-Specific Expression of Secreted Versus Membrane Forms of Immunoglobulin Gamma 2b mRNA Involves Selective Use of Alternate Polyadenylation Sites

1985 • 22 citations