Somatostatin

Hypothalamic Polypeptide That Inhibits the Secretion of Immunoreactive Pituitary Growth Hormone

1973 • 3,509 citations

Peptidergic neurones

1980 • 1,523 citations

Growth Hormone-Releasing Factor from a Human Pancreatic Tumor That Caused Acromegaly

1982 • 1,263 citations

Characterization of a growth hormone-releasing factor from a human pancreatic islet tumour

1982 • 1,092 citations

Somatomedin-C Mediates Growth Hormone Negative Feedback by Effects on Both the Hypothalamus and the Pituitary

1981 • 829 citations

GROWTH-HORMONE RELEASE-INHIBITING HORMONE IN GASTROINTESTINAL AND PANCREATIC D CELLS

1975 • 520 citations

Somatostatin in Hypothalamus, Extrahypothalamic Brain, and Peripheral Tissues of the Rat*

1978 • 474 citations

Occurrence of somatostatin-like immunoreactivity in some peripheral sympathetic noradrenergic neurons

1977 • 466 citations

Peptide neurons in the vagus, splanchnic and sciatic nerves*

1978 • 443 citations

Stimulatory and Inhibitory Effects of Purified Hypothalamic Extracts on Growth Hormone Release from Rat Pituitaryin Vitro¹

1968 • 429 citations

Cloning and sequence analysis of cDNAs encoding two distinct somatostatin precursors found in the endocrine pancreas of anglerfish

1980 • 337 citations

Immunoreactive somatostatin is present in discrete cells of the endocrine pancreas.

1975 • 335 citations

Pancreatic Neuroendocrinology: Peripheral Neural Mechanisms in the Regulation of the Islets of Langerhans*

1981 • 313 citations

Effects of Somatostatin on the Secretion of Thyrotropin and Prolactin

1974 • 297 citations

Human somatostatin I: sequence of the cDNA.

1982 • 279 citations

Distribution of somatostatin in the rat brain: Telencephalon and diencephalon

1980 • 279 citations

Human Growth Hormone and Somatomedin C Suppress the Spontaneous Release of Growth Hormone in Unanesthetized Rats*

1983 • 277 citations

Physiological role of somatostatin in the control of growth hormone and thyrotropin secretion

1976 • 241 citations

The Evolutionary Origins of Hormones, Neurotransmitters, and Other Extracellular Chemical Messengers

1982 • 227 citations

Selective effects of somatostatin-14, -25 and -28 on in vitro insulin and glucagon secretion

1981 • 206 citations

Physiological roles of somatocrinin and somatostatin in the regulation of growth hormone secretion

1982 • 198 citations

Evidence for the D-Cell of the Pancreas Secreting Somatostatin

1975 • 183 citations

Blockade of the Stress-Induced Decrease in Blood GH by Anti-Somatostatin Serum in Rats¹

1976 • 168 citations

SOMATOSTATINERGIC NEURONS IN ANTERIOR HYPOTHALAMUS: IMMUNOHISTOCHEMICAL LOCALIZATION¹

1976 • 167 citations

Effects of Growth Hormone Excess and Deficiency on Hypothalamic Somatostatin Content and Release and on Tissue Somatostatin Distribution*

1981 • 164 citations

Antiserum to Somatostatin Reverses Starvation-Induced Inhibition of Growth Hormone but Not Insulin Secretion*

1978 • 163 citations

Antiserum to Somatostatin Prevents Stress-Induced Inhibition of Growth Hormone Secretion in the Rat

1976 • 163 citations

Anatomic and phylogenetic distribution of somatostatin

1976 • 161 citations

INTRAVENTRICULARLY INJECTED GROWTH HORMONE STIMULATES SOMATOSTATIN RELEASE INTO RAT HYPOPHYSIAL PORTAL BLOOD

1981 • 156 citations

Somatostatin-like immunoreactivity in the retina.

1980 • 147 citations

Somatostatin-28 encoded in a cloned cDNA obtained from a rat medullary thyroid carcinoma.

1982 • 144 citations

Single cellular origin of somatostatin and calcitonin in the rat thyroid gland

1977 • 142 citations

EVIDENCE FOR AUTOREGULATION OF GROWTH HORMONE SECRETION VIA THE CENTRAL NERVOUS SYSTEM

1980 • 139 citations

Chromatographic and Biological Properties of Immunoreactive Somatostatin in Hypothalamic and Extrahypothalamic Brain Regions of the Rat*

1979 • 129 citations

Somatostatin and the Gastrointestinal Tract

1980 • 128 citations

STIMULATION BY GROWTH HORMONE OF SOMATOSTATIN RELEASE FROM THE RAT HYPOTHALAMUS IN VITRO

1978 • 112 citations

Inhibition by Somatostatin of Basal Levels of Serum Thyrotropin (TSH) in Normal Men

1975 • 112 citations

Effects of Brain Lesions and Hypothalamic Deafferentation on Somatostatin Distribution in the Rat Brain

1977 • 106 citations

The Effects of Lateral Hypothalamic-Medial Forebrain Stimulation and Somatostatin Antiserum on Pulsatile Growth Hormone Secretion in Freely Behaving Rats: Evidence for a Dual Regulatory Mechanism*

1981 • 101 citations

Synthesis and biological actions of prosomatostatin.

1980 • 100 citations

The Effect of Alterations in the Pituitary-Thyroid Axis on Hypothalamic Content and in Vitro Release of Somatostatin-Like Immunoreactivity*

1980 • 95 citations

Effects of neurotransmitters and cyclic AMP on somatostatin release from cultured cerebral cortical cells

1982 • 93 citations

Peptidergic Nervous Systems in the Gut

1980 • 89 citations

Inhibition of thein VitroSecretion of Insulin by an Extract of Pancreaticα₁Cells

1969 • 86 citations

Gastrointestinal Cells Producing Endocrine, Neurocrine and Paracrine Messengers

1980 • 86 citations

Somatostatin-immunoreactive fiber projections into the brain stem and the spinal cord of the rat

1981 • 86 citations

Somatostatin production by rat cerebral neurones in dissociated cell culture

1980 • 84 citations

Circulating Somatostatin Acts on the Islets of Langerhans by Way of a Somatostatin-Poor Compartment

1982 • 84 citations

Immunoreactive and biologically active somatostatin-like material in rat retina.

1979 • 78 citations

Studies on the Mechanism of Growth Hormone and Thyrotropin Responses to Somatostatin Antiserum in Anesthetized Rats*

1978 • 69 citations

Somatostatin in the auditory system of the rat

1981 • 59 citations

The Effect of Somatostatin on TSH Levels in Patients with Primary Hypothyroidism

1975 • 57 citations

Somatostatin: Regulation of Secretion

1981 • 55 citations

Biosynthesis of immunoreactive somatostatin by hypothalamic neurons in culture.

1982 • 55 citations

Immunohistochemical demonstration of somatostatin-containing cells in the human, dog and rat thyroids.

1977 • 54 citations

Somatostatin and diabetes

1981 • 53 citations

Phylogenetic aspects of somatostatin in the gastroenteropancreatic (GEP) endocrine system

1978 • 53 citations

Somatostatin-Like Immunoactivity and Biological Activity Is Present in Tetrahymena pyriformis, a Ciliated Protozoan*

1982 • 50 citations

Sodium- and Calcium-Dependent Somatostatin Release from Dissociated Cerebral Cortical Cells in Culture*

1982 • 45 citations

Gastrointestinal secretory, motor, circulatory, and metabolic effects of prosomatostatin.

1981 • 44 citations

An Intrarenal Effect of Somatostatin on Water Excretion1

1977 • 43 citations

INHIBITION OF FRUSEMIDE-INDUCED HYPERRENINÆMIA BY GROWTH-HORMONE RELEASE-INHIBITING HORMONE IN MAN

1976 • 40 citations

SOMATOSTATIN INHIBITS THE PENTAGASTRIN‐INDUCED RELEASE OF SERUM CALCITONIN IN MEDULLARY CARCINOMA OF THE THYROID

1978 • 37 citations

Somatostatin: Occurrence in Urinary Bladder Epithelium and Renal Tubules of the Toad, Bufo marinus

1980 • 36 citations

ACTIONS OF GROWTH HORMONE-RELEASE INHIBITING HORMONE (SOMATOSTATIN) ON THE RENIN ALDOSTERONE SYSTEM

1976 • 33 citations

Phylogenetic Distribution and Function of the Hypophysiotropic Hormones of the Hypothalamus

1978 • 33 citations

Cell-free biosynthesis of somatostatin precursors: Evidence for multiple forms of preprosomatostatin.

1982 • 31 citations

Somatostatin: an endogenous peptide in the toad urinary bladder inhibits vasopressin-stimulated water flow.

1980 • 28 citations

THE CHARACTERIZATION OF GROWTH HORMONE RELEASE INHIBITING HORMONE‐LIKE IMMUNOREACTIVITY IN NORMAL URINE

1977 • 28 citations

Immunoreactive Somatostatin Distribution and Axoplasmic Transport in Rat Peripheral Nerve*

1981 • 27 citations

Immunohistochemical Localization of Somatostatin

1980 • 26 citations

Immunocytochemical evidence for the presence of somatostatin-like immunoreactivity in scattered cells of the duct system of the submandibular glands in the Monkey, Macaca irus

1980 • 23 citations