Cloning and sequence analysis of cDNAs encoding two distinct somatostatin precursors found in the endocrine pancreas of anglerfish

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

Method for detection of specific RNAs in agarose gels by transfer to diazobenzyloxymethyl-paper and hybridization with DNA probes.

1977 • 2,233 citations

Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursor

1979 • 1,758 citations

Methylmercury as a reversible denaturing agent for agarose gel electrophoresis

1976 • 1,323 citations

Rat Insulin Genes: Construction of Plasmids Containing the Coding Sequences

1977 • 1,252 citations

Immunohistochemical evidence for separate populations of somatostatin-containing and substance P-containing primary afferent neurons in the rat

1976 • 758 citations

The Regional Distribution of Somatostatin in the Rat Brain

1975 • 594 citations

INHIBITION OF GASTRIN AND GASTRIC-ACID SECRETION BY GROWTH-HORMONE RELEASE-INHIBITING HORMONE

1974 • 565 citations

GROWTH-HORMONE RELEASE-INHIBITING HORMONE IN GASTROINTESTINAL AND PANCREATIC D CELLS

1975 • 520 citations

Somatostatin: Hypothalamic Inhibitor of the Endocrine Pancreas

1974 • 519 citations

N‐terminally extended somatostatin: The primary structure of somatostatin‐28

1980 • 516 citations

A bacterial clone synthesizing proinsulin.

1978 • 515 citations

Terminal labeling and addition of homopolymer tracts to duplex DNA fragments by terminal deoxynudeotidyl transferase

1976 • 416 citations

Immunoreactive somatostatin is present in discrete cells of the endocrine pancreas.

1975 • 335 citations

Homology in amino-terminal sequence of precursors to pancreatic secretory proteins.

1975 • 272 citations

Somatostatin Suppresses Secretin and Pancreatic Exocrine Secretion

1975 • 268 citations

Somatostatin: Physiological and Clinical Significance

1976 • 196 citations

Cell-free synthesis of fish preproinsulin, and processing by heterologous mammalian microsomal membranes.

1977 • 182 citations

Molecular evolution of human and rabbit beta-globin mRNAs.

1977 • 157 citations

Nucleotide sequence of a cDNA clone encoding human preproinsulin

1979 • 141 citations

‘Barrel rotation’ induced by somatostatin in the non-lesioned rat

1975 • 141 citations

Effect of growth hormone-release inhibiting hormone on hormones stimulating exocrine pancreatic secretion.

1976 • 138 citations

Replication of small plasmids in extracts of Escherichia coli

1976 • 103 citations

Somatostatin: Analogs with Selected Biological Activities

1977 • 98 citations

Isolation and Characterization of Somatostatin from Anglerfish Pancreatic Islet*

1979 • 94 citations

Higher molecular weight forms of immunoreactive somatostatin in mouse hypothalamic extracts: Evidence of processing in vitro

1979 • 88 citations

Identification of prosomatostatin in pancreatic islets.

1980 • 80 citations

Evidence for the Existence of a Biosynthetic Precursor for Somatostatin

1979 • 77 citations

Immunohistochemical localization of somatostatin, insulin and glucagon in the principal islets of the anglerfish (Lophius americanus) and the channel catfish (Ictalurus punctata)

1976 • 67 citations

Pre-prosomatostatins. Products of cell-free translations of messenger RNAs from anglerfish islets.

1980 • 66 citations

Multiple forms of somatostatin‐like immunoreactivity in canine pancreas

1978 • 65 citations

Somatostatin Biosynthesis Occurs in Pancreatic Islets*

1978 • 59 citations

Investigation of larger forms of somatostatin in pigeon pancreas and rat brain

1978 • 57 citations

In vitro biosynthesis of fish islet preprosomatostatin: evidence of processing and segregation of a high molecular weight precursor.

1980 • 55 citations